Tags

Type your tag names separated by a space and hit enter

Use of sibutramine to assist obese women with weight loss can be successful in dietitian-led clinics: another tool in the dietitian's toolbox.
J Hum Nutr Diet 2008; 21(3):248-55JH

Abstract

BACKGROUND

This study investigated differences in weight loss outcomes in obese women with Type 2 diabetes (T2D) compared to those without T2D attending a 6-month dietetic led 'Lifestyle' intervention. In those who had failed to reach weight loss goals using the 'Lifestyle' approach, the study further examined the effect on weight loss with the addition of sibutramine (Reductil, Abbott Laboratories, USA) over a 6-month period.

METHODS

The study comprised a case-control analysis of data from 38 obese female patients (18 with T2D) from the 'Lifestyle' and 'Pharmacotherapy' clinics attending a tertiary hospital in the UK.

RESULTS

In the 'Lifestyle' treatment groups, those with T2D lost significantly less body weight than those without T2D [5.26 kg (4.54%) versus 9.89 kg (9.55%), respectively]. For subjects who had failed to lose weight via the 'Lifestyle' intervention, the addition of sibutramine resulted in a similar weight loss compared to their pair-matched 'Lifestyle' only 'successful' counterparts (9.66% versus 9.55%).

CONCLUSIONS

Not all obese women, and those with T2D in particular, will derive benefit from 'Lifestyle' advice and those who are resistant to this treatment approach may be assisted by pharmacotherapy. Dietitians can play a role in identifying those individuals who may benefit from the use of pharmacotherapy.

Authors+Show Affiliations

Faculty of Health Science, University of Surrey, Guildford, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18477180

Citation

Barratt, R, et al. "Use of Sibutramine to Assist Obese Women With Weight Loss Can Be Successful in Dietitian-led Clinics: Another Tool in the Dietitian's Toolbox." Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association, vol. 21, no. 3, 2008, pp. 248-55.
Barratt R, Frost G, O'Boyle A, et al. Use of sibutramine to assist obese women with weight loss can be successful in dietitian-led clinics: another tool in the dietitian's toolbox. J Hum Nutr Diet. 2008;21(3):248-55.
Barratt, R., Frost, G., O'Boyle, A., Millward, J., & Truby, H. (2008). Use of sibutramine to assist obese women with weight loss can be successful in dietitian-led clinics: another tool in the dietitian's toolbox. Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association, 21(3), pp. 248-55. doi:10.1111/j.1365-277X.2008.00870.x.
Barratt R, et al. Use of Sibutramine to Assist Obese Women With Weight Loss Can Be Successful in Dietitian-led Clinics: Another Tool in the Dietitian's Toolbox. J Hum Nutr Diet. 2008;21(3):248-55. PubMed PMID: 18477180.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of sibutramine to assist obese women with weight loss can be successful in dietitian-led clinics: another tool in the dietitian's toolbox. AU - Barratt,R, AU - Frost,G, AU - O'Boyle,A, AU - Millward,J, AU - Truby,H, PY - 2008/5/15/pubmed PY - 2008/7/19/medline PY - 2008/5/15/entrez SP - 248 EP - 55 JF - Journal of human nutrition and dietetics : the official journal of the British Dietetic Association JO - J Hum Nutr Diet VL - 21 IS - 3 N2 - BACKGROUND: This study investigated differences in weight loss outcomes in obese women with Type 2 diabetes (T2D) compared to those without T2D attending a 6-month dietetic led 'Lifestyle' intervention. In those who had failed to reach weight loss goals using the 'Lifestyle' approach, the study further examined the effect on weight loss with the addition of sibutramine (Reductil, Abbott Laboratories, USA) over a 6-month period. METHODS: The study comprised a case-control analysis of data from 38 obese female patients (18 with T2D) from the 'Lifestyle' and 'Pharmacotherapy' clinics attending a tertiary hospital in the UK. RESULTS: In the 'Lifestyle' treatment groups, those with T2D lost significantly less body weight than those without T2D [5.26 kg (4.54%) versus 9.89 kg (9.55%), respectively]. For subjects who had failed to lose weight via the 'Lifestyle' intervention, the addition of sibutramine resulted in a similar weight loss compared to their pair-matched 'Lifestyle' only 'successful' counterparts (9.66% versus 9.55%). CONCLUSIONS: Not all obese women, and those with T2D in particular, will derive benefit from 'Lifestyle' advice and those who are resistant to this treatment approach may be assisted by pharmacotherapy. Dietitians can play a role in identifying those individuals who may benefit from the use of pharmacotherapy. SN - 1365-277X UR - https://www.unboundmedicine.com/medline/citation/18477180/Use_of_sibutramine_to_assist_obese_women_with_weight_loss_can_be_successful_in_dietitian_led_clinics:_another_tool_in_the_dietitian's_toolbox_ L2 - https://doi.org/10.1111/j.1365-277X.2008.00870.x DB - PRIME DP - Unbound Medicine ER -