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Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community-treated patients with schizophrenia.
Acta Psychiatr Scand. 2008 Jun; 117(6):474-8.AP

Abstract

OBJECTIVE

Ethnicity is a risk factor for tardive dyskinesia (TD) and other antipsychotic drug-induced movement disorders (ADIMD). It is unclear whether this association is mediated through genetic, environmental or cultural factors individually or in combination. This pilot study aimed to explore this interaction by determining if acculturation in migrant groups contributed to the prevalence of ADIMD.

METHOD

Culturally diverse but relatively genetically homogeneous (white Caucasian) patients with schizophrenia (n = 40) treated at a single site were assessed for the presence of ADIMD and level of acculturation.

RESULTS

Higher levels of acculturation correlated with an increased prevalence of TD and akathisia but not Parkinsonism. The level of acculturation significantly predicted TD.

CONCLUSION

This study identifies for the first time that acculturation significantly contributes to the prevalence of TD and akathisia but not Parkinsonism in culturally diverse migrant populations and must be accounted for when explaining ethnic variation in rates of ADIMD.

Authors+Show Affiliations

Northern Psychiatry Research Centre and Northern Area Mental Health Service, Melbourne, Australia. ssundram@mhri.edu.auNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18479320

Citation

Sundram, S, et al. "Acculturation Is Associated With the Prevalence of Tardive Dyskinesia and Akathisia in Community-treated Patients With Schizophrenia." Acta Psychiatrica Scandinavica, vol. 117, no. 6, 2008, pp. 474-8.
Sundram S, Lambert T, Piskulic D. Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community-treated patients with schizophrenia. Acta Psychiatr Scand. 2008;117(6):474-8.
Sundram, S., Lambert, T., & Piskulic, D. (2008). Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community-treated patients with schizophrenia. Acta Psychiatrica Scandinavica, 117(6), 474-8. https://doi.org/10.1111/j.1600-0447.2008.01183.x
Sundram S, Lambert T, Piskulic D. Acculturation Is Associated With the Prevalence of Tardive Dyskinesia and Akathisia in Community-treated Patients With Schizophrenia. Acta Psychiatr Scand. 2008;117(6):474-8. PubMed PMID: 18479320.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community-treated patients with schizophrenia. AU - Sundram,S, AU - Lambert,T, AU - Piskulic,D, PY - 2008/5/16/pubmed PY - 2008/7/9/medline PY - 2008/5/16/entrez SP - 474 EP - 8 JF - Acta psychiatrica Scandinavica JO - Acta Psychiatr Scand VL - 117 IS - 6 N2 - OBJECTIVE: Ethnicity is a risk factor for tardive dyskinesia (TD) and other antipsychotic drug-induced movement disorders (ADIMD). It is unclear whether this association is mediated through genetic, environmental or cultural factors individually or in combination. This pilot study aimed to explore this interaction by determining if acculturation in migrant groups contributed to the prevalence of ADIMD. METHOD: Culturally diverse but relatively genetically homogeneous (white Caucasian) patients with schizophrenia (n = 40) treated at a single site were assessed for the presence of ADIMD and level of acculturation. RESULTS: Higher levels of acculturation correlated with an increased prevalence of TD and akathisia but not Parkinsonism. The level of acculturation significantly predicted TD. CONCLUSION: This study identifies for the first time that acculturation significantly contributes to the prevalence of TD and akathisia but not Parkinsonism in culturally diverse migrant populations and must be accounted for when explaining ethnic variation in rates of ADIMD. SN - 1600-0447 UR - https://www.unboundmedicine.com/medline/citation/18479320/Acculturation_is_associated_with_the_prevalence_of_tardive_dyskinesia_and_akathisia_in_community_treated_patients_with_schizophrenia_ L2 - https://doi.org/10.1111/j.1600-0447.2008.01183.x DB - PRIME DP - Unbound Medicine ER -