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Size effect of se-enriched green tea particles on in vitro antioxidant and antitumor activities.
J Agric Food Chem. 2008 Jun 25; 56(12):4529-33.JA

Abstract

The antioxidant and antitumor activities (in vitro) of superfine regular and Se-enriched green tea particles with different sizes (3.52 microm and 220 nm) were investigated in this paper. The vitamin C and tea polyphenol contents of green tea in different sizes were significantly different, and amino acid and chlorophyll just changed a little. The antioxidant activity of green tea particles was evaluated by DPPH radical scavenging and linoleic acid peroxidation inhibition methods, and the antitumor activity was evaluated by antiproliferation assay on HepG2, A549, and MGC803 cells. The results indicated that enrichment of selenium endowed green tea with higher antioxidant activity and antitumor activity on HepG2 and A549 cells but not on MGC803 cells. The DPPH radical scavenging rates of regular and Se-enriched green tea of 220 nm (67.87% and 69.49%, respectively) were significantly greater than that of 3.52 microm, but the inhibition of linoleic acid peroxidation for green tea of 220 nm was lower. The inhibitory rates of green tea of 220 nm on HepG2, A549, and MGC803 cells achieved 77.35%, 80.76%, and 87.54% for regular green tea, and 82.51%, 88.09%, and 74.48% for Se-enriched green tea at the dose of 100 microg mL (-1), values that were all significantly higher compared to that of 3.52 microm.

Authors+Show Affiliations

College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18491910

Citation

Li, Huajia, et al. "Size Effect of Se-enriched Green Tea Particles On in Vitro Antioxidant and Antitumor Activities." Journal of Agricultural and Food Chemistry, vol. 56, no. 12, 2008, pp. 4529-33.
Li H, Li F, Yang F, et al. Size effect of se-enriched green tea particles on in vitro antioxidant and antitumor activities. J Agric Food Chem. 2008;56(12):4529-33.
Li, H., Li, F., Yang, F., Fang, Y., Xin, Z., Zhao, L., & Hu, Q. (2008). Size effect of se-enriched green tea particles on in vitro antioxidant and antitumor activities. Journal of Agricultural and Food Chemistry, 56(12), 4529-33. https://doi.org/10.1021/jf0731200
Li H, et al. Size Effect of Se-enriched Green Tea Particles On in Vitro Antioxidant and Antitumor Activities. J Agric Food Chem. 2008 Jun 25;56(12):4529-33. PubMed PMID: 18491910.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Size effect of se-enriched green tea particles on in vitro antioxidant and antitumor activities. AU - Li,Huajia, AU - Li,Feng, AU - Yang,Fangmei, AU - Fang,Yong, AU - Xin,Zhihong, AU - Zhao,Liyan, AU - Hu,Qiuhui, Y1 - 2008/05/21/ PY - 2008/5/22/pubmed PY - 2008/9/3/medline PY - 2008/5/22/entrez SP - 4529 EP - 33 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 56 IS - 12 N2 - The antioxidant and antitumor activities (in vitro) of superfine regular and Se-enriched green tea particles with different sizes (3.52 microm and 220 nm) were investigated in this paper. The vitamin C and tea polyphenol contents of green tea in different sizes were significantly different, and amino acid and chlorophyll just changed a little. The antioxidant activity of green tea particles was evaluated by DPPH radical scavenging and linoleic acid peroxidation inhibition methods, and the antitumor activity was evaluated by antiproliferation assay on HepG2, A549, and MGC803 cells. The results indicated that enrichment of selenium endowed green tea with higher antioxidant activity and antitumor activity on HepG2 and A549 cells but not on MGC803 cells. The DPPH radical scavenging rates of regular and Se-enriched green tea of 220 nm (67.87% and 69.49%, respectively) were significantly greater than that of 3.52 microm, but the inhibition of linoleic acid peroxidation for green tea of 220 nm was lower. The inhibitory rates of green tea of 220 nm on HepG2, A549, and MGC803 cells achieved 77.35%, 80.76%, and 87.54% for regular green tea, and 82.51%, 88.09%, and 74.48% for Se-enriched green tea at the dose of 100 microg mL (-1), values that were all significantly higher compared to that of 3.52 microm. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/18491910/Size_effect_of_se_enriched_green_tea_particles_on_in_vitro_antioxidant_and_antitumor_activities_ L2 - https://doi.org/10.1021/jf0731200 DB - PRIME DP - Unbound Medicine ER -