Tags

Type your tag names separated by a space and hit enter

Hypomagnesemia in Ethiopians with diabetes mellitus.
Ethn Dis 2008; 18(2):147-51ED

Abstract

BACKGROUND

Magnesium, the second most abundant intracellular cation, plays a key role in cellular metabolism. Even though hypomagnesemia has been demonstrated in patients with both type 1 and type 2 diabetes elsewhere, limited information exists from African patients with diabetes mellitus.

METHODS

This was a cross-sectional study to assess the prevalence of hypomagnesemia in Ethiopian patients with type 1 and type 2 diabetes. A total of 159 subjects were included in the study (44 patients had type 1 diabetes, 69 patients had type 2, and 46 were nondiabetic controls).

RESULTS

The mean age (+/-standard error of the mean) of the subjects with type 1 diabetes, type 2 diabetes, and controls was 30.6+/-1.6, 51.3+/-1.3, and 29.0+/-1.7 years, respectively (P<.001). Patients with type 2 diabetes were significantly older than those with type 1 diabetes and controls. Basal C-peptide level and body mass index were also significantly higher in patients with type 2 diabetes (P<.001). The mean magnesium level was significantly lower in patients with diabetes than in controls (.84+/-.12 mmol/L vs 1.02+/-.17 mmol/L, P<.001). Hypomagnesemia was seen in 65% of the patients with diabetes.

CONCLUSION

The study showed that patients with diabetes mellitus have lower levels of magnesium and are therefore at increased risk of complications related to magnesium. In light of these potential complications, we recommend periodic determination of magnesium levels and appropriate magnesium replacements.

Authors+Show Affiliations

Division of Endocrinology, Diabetes and Metabolism, Wayne State University School of Medicine, Detroit, Michigan, USA. bseyoum@med.wayne.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

18507265

Citation

Seyoum, Berhane, et al. "Hypomagnesemia in Ethiopians With Diabetes Mellitus." Ethnicity & Disease, vol. 18, no. 2, 2008, pp. 147-51.
Seyoum B, Siraj ES, Saenz C, et al. Hypomagnesemia in Ethiopians with diabetes mellitus. Ethn Dis. 2008;18(2):147-51.
Seyoum, B., Siraj, E. S., Saenz, C., & Abdulkadir, J. (2008). Hypomagnesemia in Ethiopians with diabetes mellitus. Ethnicity & Disease, 18(2), pp. 147-51.
Seyoum B, et al. Hypomagnesemia in Ethiopians With Diabetes Mellitus. Ethn Dis. 2008;18(2):147-51. PubMed PMID: 18507265.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypomagnesemia in Ethiopians with diabetes mellitus. AU - Seyoum,Berhane, AU - Siraj,Elias S, AU - Saenz,Christopher, AU - Abdulkadir,Jemal, PY - 2008/5/30/pubmed PY - 2008/7/25/medline PY - 2008/5/30/entrez SP - 147 EP - 51 JF - Ethnicity & disease JO - Ethn Dis VL - 18 IS - 2 N2 - BACKGROUND: Magnesium, the second most abundant intracellular cation, plays a key role in cellular metabolism. Even though hypomagnesemia has been demonstrated in patients with both type 1 and type 2 diabetes elsewhere, limited information exists from African patients with diabetes mellitus. METHODS: This was a cross-sectional study to assess the prevalence of hypomagnesemia in Ethiopian patients with type 1 and type 2 diabetes. A total of 159 subjects were included in the study (44 patients had type 1 diabetes, 69 patients had type 2, and 46 were nondiabetic controls). RESULTS: The mean age (+/-standard error of the mean) of the subjects with type 1 diabetes, type 2 diabetes, and controls was 30.6+/-1.6, 51.3+/-1.3, and 29.0+/-1.7 years, respectively (P<.001). Patients with type 2 diabetes were significantly older than those with type 1 diabetes and controls. Basal C-peptide level and body mass index were also significantly higher in patients with type 2 diabetes (P<.001). The mean magnesium level was significantly lower in patients with diabetes than in controls (.84+/-.12 mmol/L vs 1.02+/-.17 mmol/L, P<.001). Hypomagnesemia was seen in 65% of the patients with diabetes. CONCLUSION: The study showed that patients with diabetes mellitus have lower levels of magnesium and are therefore at increased risk of complications related to magnesium. In light of these potential complications, we recommend periodic determination of magnesium levels and appropriate magnesium replacements. SN - 1049-510X UR - https://www.unboundmedicine.com/medline/citation/18507265/Hypomagnesemia_in_Ethiopians_with_diabetes_mellitus_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -