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Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders.
J Clin Psychiatry. 2008; 69 Suppl 4:15-20.JC

Abstract

Atypical antipsychotics are emerging as the first-line pharmacologic treatment for irritability (i.e., aggression, self-injurious behavior, and severe tantrums) in children and adolescents with autistic and other pervasive developmental disorders. Results from placebo-controlled and open-label studies of clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole in this subject population are reviewed. Additional placebo-controlled trials and studies of longer-term safety and tolerability are needed.

Authors+Show Affiliations

Department of Psychiatry, Indiana University School of Medicine, Christian Sarkine Autism Treatment Center, James Whitcomb Riley Hospital for Children, Indianapolis, IN 46202-4800, USA. cmcdougl@iupui.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

18533764

Citation

McDougle, Christopher J., et al. "Atypical Antipsychotics in Children and Adolescents With Autistic and Other Pervasive Developmental Disorders." The Journal of Clinical Psychiatry, vol. 69 Suppl 4, 2008, pp. 15-20.
McDougle CJ, Stigler KA, Erickson CA, et al. Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders. J Clin Psychiatry. 2008;69 Suppl 4:15-20.
McDougle, C. J., Stigler, K. A., Erickson, C. A., & Posey, D. J. (2008). Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders. The Journal of Clinical Psychiatry, 69 Suppl 4, 15-20.
McDougle CJ, et al. Atypical Antipsychotics in Children and Adolescents With Autistic and Other Pervasive Developmental Disorders. J Clin Psychiatry. 2008;69 Suppl 4:15-20. PubMed PMID: 18533764.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders. AU - McDougle,Christopher J, AU - Stigler,Kimberly A, AU - Erickson,Craig A, AU - Posey,David J, PY - 2008/6/27/pubmed PY - 2008/7/10/medline PY - 2008/6/27/entrez SP - 15 EP - 20 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 69 Suppl 4 N2 - Atypical antipsychotics are emerging as the first-line pharmacologic treatment for irritability (i.e., aggression, self-injurious behavior, and severe tantrums) in children and adolescents with autistic and other pervasive developmental disorders. Results from placebo-controlled and open-label studies of clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole in this subject population are reviewed. Additional placebo-controlled trials and studies of longer-term safety and tolerability are needed. SN - 1555-2101 UR - https://www.unboundmedicine.com/medline/citation/18533764/Atypical_antipsychotics_in_children_and_adolescents_with_autistic_and_other_pervasive_developmental_disorders_ L2 - http://www.psychiatrist.com/jcp/article/pages/2008/v69s04/v69s0403.aspx DB - PRIME DP - Unbound Medicine ER -