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Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China.
Am J Trop Med Hyg. 2008 Jun; 78(6):968-72.AJ

Abstract

Scrub typhus, caused by Orientia tsutsugamushi, is a zoonosis that spreads rapidly in Shandong, China. To investigate the molecular characterization of O. tsutsugamushi in new and old epidemic areas in Shandong Province, we compared the genetic relationships of O. tsutsugamushi between Linyi and Tai'an districts, typical old and new epidemic areas in Shandong, respectively. O. tsutsugamushi was detected in blood from 12 of 16 patients in Linyi and in eschar from 3 of 4 patients in Tai'an; 17 of 128 rodents were found to be infected with O. tsutsugamushi in Linyi, and 4 of 68 rodents were found to be O. tsutsugamushi-positive in Tai'an. The results indicated less genetic variation in O. tsutsugamushi between the new and old epidemic areas, and the Sdu-1 type, similar to Japan Kawasaki, was the main genotype of O. tsutsugamushi in Shandong Province.

Authors+Show Affiliations

Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18541778

Citation

Yang, Li-Ping, et al. "Comparative Analysis of Nucleotide Sequences of Orientia Tsutsugamushi in Different Epidemic Areas of Scrub Typhus in Shandong, China." The American Journal of Tropical Medicine and Hygiene, vol. 78, no. 6, 2008, pp. 968-72.
Yang LP, Zhao ZT, Li Z, et al. Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China. Am J Trop Med Hyg. 2008;78(6):968-72.
Yang, L. P., Zhao, Z. T., Li, Z., Wang, X. J., Liu, Y. X., & Bi, P. (2008). Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China. The American Journal of Tropical Medicine and Hygiene, 78(6), 968-72.
Yang LP, et al. Comparative Analysis of Nucleotide Sequences of Orientia Tsutsugamushi in Different Epidemic Areas of Scrub Typhus in Shandong, China. Am J Trop Med Hyg. 2008;78(6):968-72. PubMed PMID: 18541778.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China. AU - Yang,Li-Ping, AU - Zhao,Zhong-Tang, AU - Li,Zhong, AU - Wang,Xian-Jun, AU - Liu,Yun-Xi, AU - Bi,Peng, PY - 2008/6/11/pubmed PY - 2008/8/7/medline PY - 2008/6/11/entrez SP - 968 EP - 72 JF - The American journal of tropical medicine and hygiene JO - Am J Trop Med Hyg VL - 78 IS - 6 N2 - Scrub typhus, caused by Orientia tsutsugamushi, is a zoonosis that spreads rapidly in Shandong, China. To investigate the molecular characterization of O. tsutsugamushi in new and old epidemic areas in Shandong Province, we compared the genetic relationships of O. tsutsugamushi between Linyi and Tai'an districts, typical old and new epidemic areas in Shandong, respectively. O. tsutsugamushi was detected in blood from 12 of 16 patients in Linyi and in eschar from 3 of 4 patients in Tai'an; 17 of 128 rodents were found to be infected with O. tsutsugamushi in Linyi, and 4 of 68 rodents were found to be O. tsutsugamushi-positive in Tai'an. The results indicated less genetic variation in O. tsutsugamushi between the new and old epidemic areas, and the Sdu-1 type, similar to Japan Kawasaki, was the main genotype of O. tsutsugamushi in Shandong Province. SN - 1476-1645 UR - https://www.unboundmedicine.com/medline/citation/18541778/Comparative_analysis_of_nucleotide_sequences_of_Orientia_tsutsugamushi_in_different_epidemic_areas_of_scrub_typhus_in_Shandong_China_ L2 - http://www.diseaseinfosearch.org/result/7277 DB - PRIME DP - Unbound Medicine ER -