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Evaluation of polyphenol composition in red leaves from different varieties of Vitis vinifera.
Planta Med. 2008 Apr; 74(5):565-72.PM

Abstract

In order to evaluate sustainable sources of high-quality pharmaceutical starting material, a comparative study of 135 samples of red vine leaves of different origin was conducted to determine flavonol, anthocyanin and polyphenol contents. Total flavonol content was found to be between 0.6 % and 3.5 %, anthocyanin content between 0.2 % and 1.45 % and polyphenol content between 4.6 % and 18.9 %. The results are discussed in view of published data on red vine leaf components. In order to define the optimum timeframe for collecting leaves without damaging their grape-bearing vines the ontogenetic development of red vine leaves constituents was studied. High-performance liquid chromatography (HPLC) methods used for determining anthocyanins and flavonols in red vine leaves were validated and findings were compared to results produced by assays described in the French Pharmacopoeia. Whereas the correlation between conventional photometric and HPLC methods was satisfactory for anthocyanins, the correlation between the pharmacopoeia assay for total polyphenols and the HPLC analysis for flavonols was poor. As flavonol compounds are considered relevant for the vasoprotective effect of red vine leaves, their content in starting material used in the production of herbal medicines needs to be quantified.

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Authors+Show Affiliations

Schneider E
Dr. Ernst Schneider PhytoConsulting, Seeblick 11, Marklkofen-Freinberg, Germany. schneider.e@phyto-consulting.de
von der Heydt H
No affiliation info available
Esperester A
No affiliation info available

MeSH

AgricultureChromatography, High Pressure LiquidFlavonoidsPhenolsPlant LeavesPolyphenolsTime FactorsVitis

Pub Type(s)

Comparative Study
Journal Article
Validation Study

Language

eng

PubMed ID

18543154

Citation

Schneider, Ernst, et al. "Evaluation of Polyphenol Composition in Red Leaves From Different Varieties of Vitis Vinifera." Planta Medica, vol. 74, no. 5, 2008, pp. 565-72.
Schneider E, von der Heydt H, Esperester A. Evaluation of polyphenol composition in red leaves from different varieties of Vitis vinifera. Planta Med. 2008;74(5):565-72.
Schneider, E., von der Heydt, H., & Esperester, A. (2008). Evaluation of polyphenol composition in red leaves from different varieties of Vitis vinifera. Planta Medica, 74(5), 565-72. https://doi.org/10.1055/s-2008-1034370
Schneider E, von der Heydt H, Esperester A. Evaluation of Polyphenol Composition in Red Leaves From Different Varieties of Vitis Vinifera. Planta Med. 2008;74(5):565-72. PubMed PMID: 18543154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of polyphenol composition in red leaves from different varieties of Vitis vinifera. AU - Schneider,Ernst, AU - von der Heydt,Holger, AU - Esperester,Anke, PY - 2008/6/11/pubmed PY - 2008/8/30/medline PY - 2008/6/11/entrez SP - 565 EP - 72 JF - Planta medica JO - Planta Med VL - 74 IS - 5 N2 - In order to evaluate sustainable sources of high-quality pharmaceutical starting material, a comparative study of 135 samples of red vine leaves of different origin was conducted to determine flavonol, anthocyanin and polyphenol contents. Total flavonol content was found to be between 0.6 % and 3.5 %, anthocyanin content between 0.2 % and 1.45 % and polyphenol content between 4.6 % and 18.9 %. The results are discussed in view of published data on red vine leaf components. In order to define the optimum timeframe for collecting leaves without damaging their grape-bearing vines the ontogenetic development of red vine leaves constituents was studied. High-performance liquid chromatography (HPLC) methods used for determining anthocyanins and flavonols in red vine leaves were validated and findings were compared to results produced by assays described in the French Pharmacopoeia. Whereas the correlation between conventional photometric and HPLC methods was satisfactory for anthocyanins, the correlation between the pharmacopoeia assay for total polyphenols and the HPLC analysis for flavonols was poor. As flavonol compounds are considered relevant for the vasoprotective effect of red vine leaves, their content in starting material used in the production of herbal medicines needs to be quantified. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/18543154/Evaluation_of_polyphenol_composition_in_red_leaves_from_different_varieties_of_Vitis_vinifera_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1034370 DB - PRIME DP - Unbound Medicine ER -