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[Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy].

Abstract

Alpha lipoic acid is important intramolecular redox system. It is coenzyme of piruvate dehydrogenase and ketoglutarate dehydrogenase. Alpha lipoic acid has enzymatic and cytoprotective effect. It has key role in citric acid cycle, as a coenzyme. Therapeutic efficacy of alpha lipoic acid in diabetic neuropathy is based on reaction with free radicals and lipophylic antioxydans properties. Clinical studies results showed efficacy and safety of alpha liponic acid application in patients with diabetic neuropathy.

Authors+Show Affiliations

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Institut za Farmakologiju, Klinicku farmakologiju i toksikologiju, Medicinski Fakultet u Sarajevu. fbecic@dic.unsa.ba

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Source

Medicinski arhiv 62:1 2008 pg 45-8

MeSH

Antioxidants
Diabetic Neuropathies
Humans
Thioctic Acid
Vitamin B Complex

Pub Type(s)

English Abstract
Journal Article
Review

Language

bos

PubMed ID

18543755

Citation

Becić, Fahir, et al. "[Pharmacological Significance of Alpha Lipoic Acid in Up to Date Treatment of Diabetic Neuropathy]." Medicinski Arhiv, vol. 62, no. 1, 2008, pp. 45-8.
Becić F, Kapić E, Rakanović-Todić M. [Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy]. Med Arh. 2008;62(1):45-8.
Becić, F., Kapić, E., & Rakanović-Todić, M. (2008). [Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy]. Medicinski Arhiv, 62(1), pp. 45-8.
Becić F, Kapić E, Rakanović-Todić M. [Pharmacological Significance of Alpha Lipoic Acid in Up to Date Treatment of Diabetic Neuropathy]. Med Arh. 2008;62(1):45-8. PubMed PMID: 18543755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy]. AU - Becić,Fahir, AU - Kapić,Elvedina, AU - Rakanović-Todić,Maida, PY - 2008/6/12/pubmed PY - 2008/7/23/medline PY - 2008/6/12/entrez SP - 45 EP - 8 JF - Medicinski arhiv JO - Med Arh VL - 62 IS - 1 N2 - Alpha lipoic acid is important intramolecular redox system. It is coenzyme of piruvate dehydrogenase and ketoglutarate dehydrogenase. Alpha lipoic acid has enzymatic and cytoprotective effect. It has key role in citric acid cycle, as a coenzyme. Therapeutic efficacy of alpha lipoic acid in diabetic neuropathy is based on reaction with free radicals and lipophylic antioxydans properties. Clinical studies results showed efficacy and safety of alpha liponic acid application in patients with diabetic neuropathy. UR - https://www.unboundmedicine.com/medline/citation/18543755/[Pharmacological_significance_of_alpha_lipoic_acid_in_up_to_date_treatment_of_diabetic_neuropathy]_ L2 - https://medlineplus.gov/diabeticnerveproblems.html DB - PRIME DP - Unbound Medicine ER -