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Secondary syphilis presenting as annular lichenoid plaques on the scrotum.
J Cutan Med Surg. 2008 May-Jun; 12(3):114-6.JC

Abstract

BACKGROUND

Secondary syphilis can have protean clinical manifestations and can present with unusual lesions, which may go unrecognized.

METHODS

We report two cases of secondary syphilis with annular lichenoid plaques on the scrotum associated with generalized lymphadenopathy, fever, and malaise.

RESULTS AND CONCLUSIONS

The serology revealed a reactive Venereal Disease Research Laboratory test and a positive Treponema pallidum hemagglutination assay. The human immunodeficiency virus (HIV) serology was nonreactive. The lesions cleared with a single dose of benzathine penicillin, 2.4 million units, given intramuscularly. The presentations of syphilis, often described as "the great imitator," can be varied and atypical. Increased clinical vigilance and awareness of the varied modes of presentation are needed to prevent missing this highly treatable, potentially serious condition.

Authors+Show Affiliations

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18544293

Citation

Narang, Tarun, et al. "Secondary Syphilis Presenting as Annular Lichenoid Plaques On the Scrotum." Journal of Cutaneous Medicine and Surgery, vol. 12, no. 3, 2008, pp. 114-6.
Narang T, De D, Dogra S, et al. Secondary syphilis presenting as annular lichenoid plaques on the scrotum. J Cutan Med Surg. 2008;12(3):114-6.
Narang, T., De, D., Dogra, S., Kanwar, A. J., & Saikia, U. N. (2008). Secondary syphilis presenting as annular lichenoid plaques on the scrotum. Journal of Cutaneous Medicine and Surgery, 12(3), 114-6.
Narang T, et al. Secondary Syphilis Presenting as Annular Lichenoid Plaques On the Scrotum. J Cutan Med Surg. 2008 May-Jun;12(3):114-6. PubMed PMID: 18544293.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Secondary syphilis presenting as annular lichenoid plaques on the scrotum. AU - Narang,Tarun, AU - De,Dipankar, AU - Dogra,Sunil, AU - Kanwar,Amrinder Jit, AU - Saikia,Uma Nahar, PY - 2008/6/12/pubmed PY - 2008/8/30/medline PY - 2008/6/12/entrez SP - 114 EP - 6 JF - Journal of cutaneous medicine and surgery JO - J Cutan Med Surg VL - 12 IS - 3 N2 - BACKGROUND: Secondary syphilis can have protean clinical manifestations and can present with unusual lesions, which may go unrecognized. METHODS: We report two cases of secondary syphilis with annular lichenoid plaques on the scrotum associated with generalized lymphadenopathy, fever, and malaise. RESULTS AND CONCLUSIONS: The serology revealed a reactive Venereal Disease Research Laboratory test and a positive Treponema pallidum hemagglutination assay. The human immunodeficiency virus (HIV) serology was nonreactive. The lesions cleared with a single dose of benzathine penicillin, 2.4 million units, given intramuscularly. The presentations of syphilis, often described as "the great imitator," can be varied and atypical. Increased clinical vigilance and awareness of the varied modes of presentation are needed to prevent missing this highly treatable, potentially serious condition. SN - 1203-4754 UR - https://www.unboundmedicine.com/medline/citation/18544293/Secondary_syphilis_presenting_as_annular_lichenoid_plaques_on_the_scrotum_ L2 - https://journals.sagepub.com/doi/10.2310/7750.2007.00043?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -