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[The morphometric and immunohistochemical characteristics of the gastric and duodenal mucosa in systemic lupus erythematosus].
Biull Eksp Biol Med. 1991 Feb; 111(2):203-6.BE

Abstract

Histological, morphometric, and immunohistochemical studies of biopsy specimens from the mucosa of the body and antral portion of the stomach, the bulb and descending portion of the duodenum were performed in 27 children with systemic lupus erythematosis (SLE) and in 12 with chronic gastroduodenitis. The inflammatory infiltrate from SLE patients was found to contain higher levels of young and mature fibroblasts than that from patients with chronic gastroduodenitis, mature fibroblasts being prevalent. The inflammatory changes in the gastric and duodenal mucosa were ascertained to be associated with the progression of SLE. In exacerbation of SLE, the walls of vessels (arterioles) exhibited immune complexes classified mainly as IgG and, to a lesser degree, as IgM. In remission, the luminescence of the vessels decreased. The serum level of immunoglobins did not correlate with their regional production in the gastric and duodenal mucosa.

Authors

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Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

1854972

Citation

Musaev, S N., et al. "[The Morphometric and Immunohistochemical Characteristics of the Gastric and Duodenal Mucosa in Systemic Lupus Erythematosus]." Biulleten' Eksperimental'noi Biologii I Meditsiny, vol. 111, no. 2, 1991, pp. 203-6.
Musaev SN, Novikova AV, Shershevskaia AIa, et al. [The morphometric and immunohistochemical characteristics of the gastric and duodenal mucosa in systemic lupus erythematosus]. Biull Eksp Biol Med. 1991;111(2):203-6.
Musaev, S. N., Novikova, A. V., Shershevskaia, A. I. a., Klimanskaia, E. V., & Aksenova, I. V. (1991). [The morphometric and immunohistochemical characteristics of the gastric and duodenal mucosa in systemic lupus erythematosus]. Biulleten' Eksperimental'noi Biologii I Meditsiny, 111(2), 203-6.
Musaev SN, et al. [The Morphometric and Immunohistochemical Characteristics of the Gastric and Duodenal Mucosa in Systemic Lupus Erythematosus]. Biull Eksp Biol Med. 1991;111(2):203-6. PubMed PMID: 1854972.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The morphometric and immunohistochemical characteristics of the gastric and duodenal mucosa in systemic lupus erythematosus]. AU - Musaev,S N, AU - Novikova,A V, AU - Shershevskaia,A Ia, AU - Klimanskaia,E V, AU - Aksenova,I V, PY - 1991/2/1/pubmed PY - 1991/2/1/medline PY - 1991/2/1/entrez SP - 203 EP - 6 JF - Biulleten' eksperimental'noi biologii i meditsiny JO - Biull Eksp Biol Med VL - 111 IS - 2 N2 - Histological, morphometric, and immunohistochemical studies of biopsy specimens from the mucosa of the body and antral portion of the stomach, the bulb and descending portion of the duodenum were performed in 27 children with systemic lupus erythematosis (SLE) and in 12 with chronic gastroduodenitis. The inflammatory infiltrate from SLE patients was found to contain higher levels of young and mature fibroblasts than that from patients with chronic gastroduodenitis, mature fibroblasts being prevalent. The inflammatory changes in the gastric and duodenal mucosa were ascertained to be associated with the progression of SLE. In exacerbation of SLE, the walls of vessels (arterioles) exhibited immune complexes classified mainly as IgG and, to a lesser degree, as IgM. In remission, the luminescence of the vessels decreased. The serum level of immunoglobins did not correlate with their regional production in the gastric and duodenal mucosa. SN - 0365-9615 UR - https://www.unboundmedicine.com/medline/citation/1854972/[The_morphometric_and_immunohistochemical_characteristics_of_the_gastric_and_duodenal_mucosa_in_systemic_lupus_erythematosus]_ L2 - https://www.diseaseinfosearch.org/result/9373 DB - PRIME DP - Unbound Medicine ER -