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Determination of risk factors for deep venous thrombosis in hospitalized children.
J Pediatr Surg 2008; 43(6):1095-9JP

Abstract

PURPOSE

Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients.

METHODS

This cross-sectional study used the data from the Health Care Cost and Utilization Project Kids' Inpatient Database for the years of 1997, 2000, and 2003 to estimate the DVT prevalence and crude and adjusted prevalence ratios. Patients between the ages of 1 and 17 years and who were hospitalized for at least 4 days were included.

RESULTS

The weighted prevalence of DVT was 4.2 per 1000 hospital discharges (95% confidence interval [CI], 3.4-3.7). Independent of age, the prevalence of DVT was significantly greater in 2000 and 2003 compared to 1997, prevalence ratio (PR) of 1.2 and 1.4 (95% CI, 1.1-1.3 and 1.2-1.4). Using only the 2003 database, adjusted analysis revealed that patients at highest risk were those in the age range of 15 to 17 years (PR, 2.0; 95% CI, 1.6-2.4) and with the following comorbid conditions: obesity (PR, 2.1; 95% CI, 1.5-2.8), inflammatory bowel disease (PR, 1.8; 95% CI, 1.2-2.7), hematologic malignancy (PR, 2.5; 95% CI, 2.0-3.1), and thoracoabdominal (PR, 1.8; 95% CI, 1.6-2.2) or orthopedic (PR, 2.2; 95% CI, 1.7-2.8) operations. Predictors not associated with DVT included sex and diagnosis of trauma.

CONCLUSIONS

The discharge diagnosis of DVT of the lower extremities has significantly increased since 1997. In addition, teenagers with underlying disorders are at highest risk for DVT.

Authors+Show Affiliations

Division of Pediatric Surgery, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143-0570, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18558189

Citation

Vu, Lan T., et al. "Determination of Risk Factors for Deep Venous Thrombosis in Hospitalized Children." Journal of Pediatric Surgery, vol. 43, no. 6, 2008, pp. 1095-9.
Vu LT, Nobuhara KK, Lee H, et al. Determination of risk factors for deep venous thrombosis in hospitalized children. J Pediatr Surg. 2008;43(6):1095-9.
Vu, L. T., Nobuhara, K. K., Lee, H., & Farmer, D. L. (2008). Determination of risk factors for deep venous thrombosis in hospitalized children. Journal of Pediatric Surgery, 43(6), pp. 1095-9. doi:10.1016/j.jpedsurg.2008.02.036.
Vu LT, et al. Determination of Risk Factors for Deep Venous Thrombosis in Hospitalized Children. J Pediatr Surg. 2008;43(6):1095-9. PubMed PMID: 18558189.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Determination of risk factors for deep venous thrombosis in hospitalized children. AU - Vu,Lan T, AU - Nobuhara,Kerilyn K, AU - Lee,Hanmin, AU - Farmer,Diana L, PY - 2008/02/04/received PY - 2008/02/09/accepted PY - 2008/6/19/pubmed PY - 2008/8/30/medline PY - 2008/6/19/entrez SP - 1095 EP - 9 JF - Journal of pediatric surgery JO - J. Pediatr. Surg. VL - 43 IS - 6 N2 - PURPOSE: Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients. METHODS: This cross-sectional study used the data from the Health Care Cost and Utilization Project Kids' Inpatient Database for the years of 1997, 2000, and 2003 to estimate the DVT prevalence and crude and adjusted prevalence ratios. Patients between the ages of 1 and 17 years and who were hospitalized for at least 4 days were included. RESULTS: The weighted prevalence of DVT was 4.2 per 1000 hospital discharges (95% confidence interval [CI], 3.4-3.7). Independent of age, the prevalence of DVT was significantly greater in 2000 and 2003 compared to 1997, prevalence ratio (PR) of 1.2 and 1.4 (95% CI, 1.1-1.3 and 1.2-1.4). Using only the 2003 database, adjusted analysis revealed that patients at highest risk were those in the age range of 15 to 17 years (PR, 2.0; 95% CI, 1.6-2.4) and with the following comorbid conditions: obesity (PR, 2.1; 95% CI, 1.5-2.8), inflammatory bowel disease (PR, 1.8; 95% CI, 1.2-2.7), hematologic malignancy (PR, 2.5; 95% CI, 2.0-3.1), and thoracoabdominal (PR, 1.8; 95% CI, 1.6-2.2) or orthopedic (PR, 2.2; 95% CI, 1.7-2.8) operations. Predictors not associated with DVT included sex and diagnosis of trauma. CONCLUSIONS: The discharge diagnosis of DVT of the lower extremities has significantly increased since 1997. In addition, teenagers with underlying disorders are at highest risk for DVT. SN - 1531-5037 UR - https://www.unboundmedicine.com/medline/citation/18558189/Determination_of_risk_factors_for_deep_venous_thrombosis_in_hospitalized_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3468(08)00173-5 DB - PRIME DP - Unbound Medicine ER -