Tags

Type your tag names separated by a space and hit enter

Determination of risk factors for deep venous thrombosis in hospitalized children.

Abstract

PURPOSE

Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients.

METHODS

This cross-sectional study used the data from the Health Care Cost and Utilization Project Kids' Inpatient Database for the years of 1997, 2000, and 2003 to estimate the DVT prevalence and crude and adjusted prevalence ratios. Patients between the ages of 1 and 17 years and who were hospitalized for at least 4 days were included.

RESULTS

The weighted prevalence of DVT was 4.2 per 1000 hospital discharges (95% confidence interval [CI], 3.4-3.7). Independent of age, the prevalence of DVT was significantly greater in 2000 and 2003 compared to 1997, prevalence ratio (PR) of 1.2 and 1.4 (95% CI, 1.1-1.3 and 1.2-1.4). Using only the 2003 database, adjusted analysis revealed that patients at highest risk were those in the age range of 15 to 17 years (PR, 2.0; 95% CI, 1.6-2.4) and with the following comorbid conditions: obesity (PR, 2.1; 95% CI, 1.5-2.8), inflammatory bowel disease (PR, 1.8; 95% CI, 1.2-2.7), hematologic malignancy (PR, 2.5; 95% CI, 2.0-3.1), and thoracoabdominal (PR, 1.8; 95% CI, 1.6-2.2) or orthopedic (PR, 2.2; 95% CI, 1.7-2.8) operations. Predictors not associated with DVT included sex and diagnosis of trauma.

CONCLUSIONS

The discharge diagnosis of DVT of the lower extremities has significantly increased since 1997. In addition, teenagers with underlying disorders are at highest risk for DVT.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Division of Pediatric Surgery, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143-0570, USA.

    , ,

    Source

    Journal of pediatric surgery 43:6 2008 Jun pg 1095-9

    MeSH

    Adolescent
    Age Distribution
    Child
    Child, Hospitalized
    Child, Preschool
    Comorbidity
    Confidence Intervals
    Cross-Sectional Studies
    Female
    Hematologic Neoplasms
    Humans
    Infant
    Inflammatory Bowel Diseases
    Logistic Models
    Male
    Multivariate Analysis
    Obesity
    Orthopedic Procedures
    Prevalence
    Probability
    Registries
    Risk Factors
    Severity of Illness Index
    Sex Distribution
    Thoracic Surgical Procedures
    Ultrasonography, Doppler
    Venous Thrombosis

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    18558189

    Citation

    Vu, Lan T., et al. "Determination of Risk Factors for Deep Venous Thrombosis in Hospitalized Children." Journal of Pediatric Surgery, vol. 43, no. 6, 2008, pp. 1095-9.
    Vu LT, Nobuhara KK, Lee H, et al. Determination of risk factors for deep venous thrombosis in hospitalized children. J Pediatr Surg. 2008;43(6):1095-9.
    Vu, L. T., Nobuhara, K. K., Lee, H., & Farmer, D. L. (2008). Determination of risk factors for deep venous thrombosis in hospitalized children. Journal of Pediatric Surgery, 43(6), pp. 1095-9. doi:10.1016/j.jpedsurg.2008.02.036.
    Vu LT, et al. Determination of Risk Factors for Deep Venous Thrombosis in Hospitalized Children. J Pediatr Surg. 2008;43(6):1095-9. PubMed PMID: 18558189.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Determination of risk factors for deep venous thrombosis in hospitalized children. AU - Vu,Lan T, AU - Nobuhara,Kerilyn K, AU - Lee,Hanmin, AU - Farmer,Diana L, PY - 2008/02/04/received PY - 2008/02/09/accepted PY - 2008/6/19/pubmed PY - 2008/8/30/medline PY - 2008/6/19/entrez SP - 1095 EP - 9 JF - Journal of pediatric surgery JO - J. Pediatr. Surg. VL - 43 IS - 6 N2 - PURPOSE: Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients. METHODS: This cross-sectional study used the data from the Health Care Cost and Utilization Project Kids' Inpatient Database for the years of 1997, 2000, and 2003 to estimate the DVT prevalence and crude and adjusted prevalence ratios. Patients between the ages of 1 and 17 years and who were hospitalized for at least 4 days were included. RESULTS: The weighted prevalence of DVT was 4.2 per 1000 hospital discharges (95% confidence interval [CI], 3.4-3.7). Independent of age, the prevalence of DVT was significantly greater in 2000 and 2003 compared to 1997, prevalence ratio (PR) of 1.2 and 1.4 (95% CI, 1.1-1.3 and 1.2-1.4). Using only the 2003 database, adjusted analysis revealed that patients at highest risk were those in the age range of 15 to 17 years (PR, 2.0; 95% CI, 1.6-2.4) and with the following comorbid conditions: obesity (PR, 2.1; 95% CI, 1.5-2.8), inflammatory bowel disease (PR, 1.8; 95% CI, 1.2-2.7), hematologic malignancy (PR, 2.5; 95% CI, 2.0-3.1), and thoracoabdominal (PR, 1.8; 95% CI, 1.6-2.2) or orthopedic (PR, 2.2; 95% CI, 1.7-2.8) operations. Predictors not associated with DVT included sex and diagnosis of trauma. CONCLUSIONS: The discharge diagnosis of DVT of the lower extremities has significantly increased since 1997. In addition, teenagers with underlying disorders are at highest risk for DVT. SN - 1531-5037 UR - https://www.unboundmedicine.com/medline/citation/18558189/Determination_of_risk_factors_for_deep_venous_thrombosis_in_hospitalized_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3468(08)00173-5 DB - PRIME DP - Unbound Medicine ER -