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C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity.

Abstract

An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures of 1-3 were determined on the basis of the analysis of their spectroscopic data. Compounds 1-4 exhibited potent superoxide-scavenging activity.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan.

    , ,

    Source

    Journal of natural products 71:7 2008 Jul pg 1308-10

    MeSH

    Angelica
    Chalcones
    Free Radical Scavengers
    Japan
    Molecular Structure
    Nuclear Magnetic Resonance, Biomolecular
    Plant Stems
    Plants, Medicinal
    Superoxides

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    18558745

    Citation

    Aoki, Nobuwa, et al. "C-geranylated Chalcones From the Stems of Angelica Keiskei With Superoxide-scavenging Activity." Journal of Natural Products, vol. 71, no. 7, 2008, pp. 1308-10.
    Aoki N, Muko M, Ohta E, et al. C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity. J Nat Prod. 2008;71(7):1308-10.
    Aoki, N., Muko, M., Ohta, E., & Ohta, S. (2008). C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity. Journal of Natural Products, 71(7), pp. 1308-10. doi:10.1021/np800187f.
    Aoki N, et al. C-geranylated Chalcones From the Stems of Angelica Keiskei With Superoxide-scavenging Activity. J Nat Prod. 2008;71(7):1308-10. PubMed PMID: 18558745.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity. AU - Aoki,Nobuwa, AU - Muko,Mai, AU - Ohta,Emi, AU - Ohta,Shinji, Y1 - 2008/06/18/ PY - 2008/6/19/pubmed PY - 2008/9/30/medline PY - 2008/6/19/entrez SP - 1308 EP - 10 JF - Journal of natural products JO - J. Nat. Prod. VL - 71 IS - 7 N2 - An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures of 1-3 were determined on the basis of the analysis of their spectroscopic data. Compounds 1-4 exhibited potent superoxide-scavenging activity. SN - 1520-6025 UR - https://www.unboundmedicine.com/medline/citation/18558745/C_geranylated_chalcones_from_the_stems_of_Angelica_keiskei_with_superoxide_scavenging_activity_ L2 - https://dx.doi.org/10.1021/np800187f DB - PRIME DP - Unbound Medicine ER -