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Occupational physical activity in relation with prostate cancer and benign prostatic hyperplasia.

Abstract

Using data from two case-control studies undertaken in Athens, Greece from 1994 to 1997, we have examined the association of occupational physical activity with the risk of prostate cancer and benign prostatic hyperplasia (BPH). Cases consisted of 320 patients with histologically confirmed incident prostate cancer and 184 patients with surgically treated BPH. Controls were 246 patients hospitalized for minor conditions. Occupations before retirement were classified, independently and blindly as to case-control status, into high, medium, and low physical activity levels. After fine controlling for years of schooling, there was a suggestive inverse association of physical activity with prostate cancer (P for trend 0.12) and a significant one with BPH (P for trend 0.04). The odds ratio (95% confidence interval) for high versus low activity was 0.69 (0.40-1.22) for prostate cancer and 0.59 (0.31-1.11) for BPH. The association of physical activity with both conditions tended to be more pronounced among men 65 years old or younger. Given the high frequency of occurrence of the examined conditions in the male population and our limited knowledge about other modifiable risk factors, preventive measures may have to focus on increasing physical activity.

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  • Authors+Show Affiliations

    ,

    Faculty of Health Professions, Athens Technological Institute, University of Athens, Athens, Greece. arlagiou@med.uoa.gr

    , , , , , ,

    Source

    MeSH

    Adult
    Age Factors
    Case-Control Studies
    Causality
    Confidence Intervals
    Exercise
    Follow-Up Studies
    Greece
    Humans
    Incidence
    Logistic Models
    Male
    Middle Aged
    Motor Activity
    Multivariate Analysis
    Occupational Exposure
    Odds Ratio
    Probability
    Prostatic Hyperplasia
    Prostatic Neoplasms
    Retrospective Studies
    Risk Assessment

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    18562958

    Citation

    Lagiou, Areti, et al. "Occupational Physical Activity in Relation With Prostate Cancer and Benign Prostatic Hyperplasia." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 17, no. 4, 2008, pp. 336-9.
    Lagiou A, Samoli E, Georgila C, et al. Occupational physical activity in relation with prostate cancer and benign prostatic hyperplasia. Eur J Cancer Prev. 2008;17(4):336-9.
    Lagiou, A., Samoli, E., Georgila, C., Minaki, P., Barbouni, A., Tzonou, A., ... Lagiou, P. (2008). Occupational physical activity in relation with prostate cancer and benign prostatic hyperplasia. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 17(4), pp. 336-9. doi:10.1097/CEJ.0b013e3282f5221e.
    Lagiou A, et al. Occupational Physical Activity in Relation With Prostate Cancer and Benign Prostatic Hyperplasia. Eur J Cancer Prev. 2008;17(4):336-9. PubMed PMID: 18562958.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Occupational physical activity in relation with prostate cancer and benign prostatic hyperplasia. AU - Lagiou,Areti, AU - Samoli,Evi, AU - Georgila,Christina, AU - Minaki,Ploumi, AU - Barbouni,Anastasia, AU - Tzonou,Anastasia, AU - Trichopoulos,Dimitrios, AU - Lagiou,Pagona, PY - 2008/6/20/pubmed PY - 2008/8/20/medline PY - 2008/6/20/entrez SP - 336 EP - 9 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur. J. Cancer Prev. VL - 17 IS - 4 N2 - Using data from two case-control studies undertaken in Athens, Greece from 1994 to 1997, we have examined the association of occupational physical activity with the risk of prostate cancer and benign prostatic hyperplasia (BPH). Cases consisted of 320 patients with histologically confirmed incident prostate cancer and 184 patients with surgically treated BPH. Controls were 246 patients hospitalized for minor conditions. Occupations before retirement were classified, independently and blindly as to case-control status, into high, medium, and low physical activity levels. After fine controlling for years of schooling, there was a suggestive inverse association of physical activity with prostate cancer (P for trend 0.12) and a significant one with BPH (P for trend 0.04). The odds ratio (95% confidence interval) for high versus low activity was 0.69 (0.40-1.22) for prostate cancer and 0.59 (0.31-1.11) for BPH. The association of physical activity with both conditions tended to be more pronounced among men 65 years old or younger. Given the high frequency of occurrence of the examined conditions in the male population and our limited knowledge about other modifiable risk factors, preventive measures may have to focus on increasing physical activity. SN - 1473-5709 UR - https://www.unboundmedicine.com/medline/citation/18562958/Occupational_physical_activity_in_relation_with_prostate_cancer_and_benign_prostatic_hyperplasia_ L2 - http://Insights.ovid.com/pubmed?pmid=18562958 DB - PRIME DP - Unbound Medicine ER -