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Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results.
Br J Dermatol. 2008 Sep; 159(3):628-32.BJ

Abstract

BACKGROUND

Rosacea is a common skin condition but the treatments currently available are not satisfactory.

OBJECTIVES

To assess the efficacy of intense pulsed light (IPL) for treatment of stage I rosacea (flushing, erythema and telangiectasia).

METHODS

Thirty-four patients were treated, 25 women and nine men, mean age 47 years. The treatment employed was IPL 515-1200 nm, with a 560 nm cut-off filter. The fluence range was 24-32 J cm(-2). Four treatments were administered on the face at 3-week intervals. Erythema values were measured at baseline and at the end of the treatment period on the cheeks and chin. Digital photographs were assessed by a consultant dermatologist on a 10-point visual analogue scale (VAS). Patients' assessments were also made using a 10-point VAS. Outcome measures were repeated 6 months after treatment.

RESULTS

After four treatments the mean reduction of the erythema values was 39% on the cheeks (P < 0.001) and 22% on the chin (P < 0.001). This was confirmed by photographic assessment where erythema improved by 46% and telangiectasia by 55% (P < 0.001). The severity of rosacea was reduced on average by 3.5 points on the 10-point VAS. Patients' and physicians' assessments of the overall improvement of rosacea were similar: more than 50% improvement was noticed in 73% and 83% of patients, respectively (P < 0.001). The results were sustained at 6 months. Side-effects were minimal and self-limiting.

CONCLUSIONS

IPL significantly reduces erythema and telangiectasia of rosacea and this is sustained for at least 6 months.

Authors+Show Affiliations

Department of Dermatology, Royal Free Hampstead NHS Trust, London NW3 2QG, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial, Phase III
Journal Article

Language

eng

PubMed ID

18565174

Citation

Papageorgiou, P, et al. "Treatment of Rosacea With Intense Pulsed Light: Significant Improvement and Long-lasting Results." The British Journal of Dermatology, vol. 159, no. 3, 2008, pp. 628-32.
Papageorgiou P, Clayton W, Norwood S, et al. Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results. Br J Dermatol. 2008;159(3):628-32.
Papageorgiou, P., Clayton, W., Norwood, S., Chopra, S., & Rustin, M. (2008). Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results. The British Journal of Dermatology, 159(3), 628-32. https://doi.org/10.1111/j.1365-2133.2008.08702.x
Papageorgiou P, et al. Treatment of Rosacea With Intense Pulsed Light: Significant Improvement and Long-lasting Results. Br J Dermatol. 2008;159(3):628-32. PubMed PMID: 18565174.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results. AU - Papageorgiou,P, AU - Clayton,W, AU - Norwood,S, AU - Chopra,S, AU - Rustin,M, Y1 - 2008/06/28/ PY - 2008/6/21/pubmed PY - 2008/12/23/medline PY - 2008/6/21/entrez SP - 628 EP - 32 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 159 IS - 3 N2 - BACKGROUND: Rosacea is a common skin condition but the treatments currently available are not satisfactory. OBJECTIVES: To assess the efficacy of intense pulsed light (IPL) for treatment of stage I rosacea (flushing, erythema and telangiectasia). METHODS: Thirty-four patients were treated, 25 women and nine men, mean age 47 years. The treatment employed was IPL 515-1200 nm, with a 560 nm cut-off filter. The fluence range was 24-32 J cm(-2). Four treatments were administered on the face at 3-week intervals. Erythema values were measured at baseline and at the end of the treatment period on the cheeks and chin. Digital photographs were assessed by a consultant dermatologist on a 10-point visual analogue scale (VAS). Patients' assessments were also made using a 10-point VAS. Outcome measures were repeated 6 months after treatment. RESULTS: After four treatments the mean reduction of the erythema values was 39% on the cheeks (P < 0.001) and 22% on the chin (P < 0.001). This was confirmed by photographic assessment where erythema improved by 46% and telangiectasia by 55% (P < 0.001). The severity of rosacea was reduced on average by 3.5 points on the 10-point VAS. Patients' and physicians' assessments of the overall improvement of rosacea were similar: more than 50% improvement was noticed in 73% and 83% of patients, respectively (P < 0.001). The results were sustained at 6 months. Side-effects were minimal and self-limiting. CONCLUSIONS: IPL significantly reduces erythema and telangiectasia of rosacea and this is sustained for at least 6 months. SN - 1365-2133 UR - https://www.unboundmedicine.com/medline/citation/18565174/Treatment_of_rosacea_with_intense_pulsed_light:_significant_improvement_and_long_lasting_results_ L2 - https://doi.org/10.1111/j.1365-2133.2008.08702.x DB - PRIME DP - Unbound Medicine ER -