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A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials.
Phytother Res 2008; 22(7):851-8PR

Abstract

Panax ginseng C.A. Meyer is a well-known medicinal herb native to China and Korea, and has been used as a herbal remedy in eastern Asia for thousands of years. However, there is different evidence of ginseng efficacy between traditional Chinese medicine (TCM), modern pharmacological experiments and clinical trials. In TCM, ginseng is a highly valued herb and has been applied to a variety of pathological conditions and illnesses such as hypodynamia, anorexia, shortness of breath, palpitation, insomnia, impotence, hemorrhage and diabetes. Modern pharmacological experiments have proved that ginseng possesses multiple constituents (ginsenosides, polysaccharides, peptides, polyacetylenic alcohols, etc.) and actions (central nervous system effects, neuroprotective effect, immunomodulation, anticancer, etc.), ginsenosides as the active ingredients, especially, having antioxidant, antiinflammatory, antiapoptotic and immunostimulant properties. Recently, ginseng has been studied in a number of randomized controlled trials investigating its effect mainly on physical and psychomotor performance, cognitive function, immunomodulation, diabetes mellitus, cardiovascular risk factors, quality of life, as well as adverse effects. Equivocal results have been demonstrated for many of these indications. Because of the poor quality of most clinical trials on ginseng, reliable clinical data in humans are still lacking. Therefore, a broader understanding of medical knowledge and reasoning on ginseng is necessary.

Authors+Show Affiliations

TCM Research Center, Tianjin University of Traditional Chinese Medicine, Anshanxi Road 312, Nankai District, Tianjin, 300193, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Historical Article
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

18567057

Citation

Xiang, Yao-Zu, et al. "A Comparison of the Ancient Use of Ginseng in Traditional Chinese Medicine With Modern Pharmacological Experiments and Clinical Trials." Phytotherapy Research : PTR, vol. 22, no. 7, 2008, pp. 851-8.
Xiang YZ, Shang HC, Gao XM, et al. A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials. Phytother Res. 2008;22(7):851-8.
Xiang, Y. Z., Shang, H. C., Gao, X. M., & Zhang, B. L. (2008). A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials. Phytotherapy Research : PTR, 22(7), pp. 851-8. doi:10.1002/ptr.2384.
Xiang YZ, et al. A Comparison of the Ancient Use of Ginseng in Traditional Chinese Medicine With Modern Pharmacological Experiments and Clinical Trials. Phytother Res. 2008;22(7):851-8. PubMed PMID: 18567057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials. AU - Xiang,Yao-Zu, AU - Shang,Hong-Cai, AU - Gao,Xiu-Mei, AU - Zhang,Bo-Li, PY - 2008/6/21/pubmed PY - 2008/8/8/medline PY - 2008/6/21/entrez SP - 851 EP - 8 JF - Phytotherapy research : PTR JO - Phytother Res VL - 22 IS - 7 N2 - Panax ginseng C.A. Meyer is a well-known medicinal herb native to China and Korea, and has been used as a herbal remedy in eastern Asia for thousands of years. However, there is different evidence of ginseng efficacy between traditional Chinese medicine (TCM), modern pharmacological experiments and clinical trials. In TCM, ginseng is a highly valued herb and has been applied to a variety of pathological conditions and illnesses such as hypodynamia, anorexia, shortness of breath, palpitation, insomnia, impotence, hemorrhage and diabetes. Modern pharmacological experiments have proved that ginseng possesses multiple constituents (ginsenosides, polysaccharides, peptides, polyacetylenic alcohols, etc.) and actions (central nervous system effects, neuroprotective effect, immunomodulation, anticancer, etc.), ginsenosides as the active ingredients, especially, having antioxidant, antiinflammatory, antiapoptotic and immunostimulant properties. Recently, ginseng has been studied in a number of randomized controlled trials investigating its effect mainly on physical and psychomotor performance, cognitive function, immunomodulation, diabetes mellitus, cardiovascular risk factors, quality of life, as well as adverse effects. Equivocal results have been demonstrated for many of these indications. Because of the poor quality of most clinical trials on ginseng, reliable clinical data in humans are still lacking. Therefore, a broader understanding of medical knowledge and reasoning on ginseng is necessary. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/18567057/A_comparison_of_the_ancient_use_of_ginseng_in_traditional_Chinese_medicine_with_modern_pharmacological_experiments_and_clinical_trials_ L2 - https://doi.org/10.1002/ptr.2384 DB - PRIME DP - Unbound Medicine ER -