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[Impact of neuroleptic-induced hyperprolactinemia on sexual dysfunction in male schizophrenic patients].
Psychiatr Pol. 2008 Jan-Feb; 42(1):87-95.PP

Abstract

Human sexual function is complex and effected in many different ways by schizophrenia and the antipsychotic drugs used in its treatment. Although not extensively researched, sexual dysfunction seems to be frequent in patients with schizophrenia, especially in men. They appear, in significant part, to be a direct consequence of dopamine antagonism, combined with indirect effects due to increased serum prolactin (PRL) concentration. All of the typical antipsychotics and risperidone can cause substantial PRL elevation. Hyperprolactinemia in male schizophrenics might decrease libido, cause anorgasmia and lead to erectile dysfunction. These sexual side effects are closely associated with the patients' willingness to take antipsychotics, and can affect compliance.

Authors+Show Affiliations

Klinika Chorób Psychicznych AM w Białymstoku.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

pol

PubMed ID

18567406

Citation

Konarzewska, Beata, et al. "[Impact of Neuroleptic-induced Hyperprolactinemia On Sexual Dysfunction in Male Schizophrenic Patients]." Psychiatria Polska, vol. 42, no. 1, 2008, pp. 87-95.
Konarzewska B, Szulc A, Popławska R, et al. [Impact of neuroleptic-induced hyperprolactinemia on sexual dysfunction in male schizophrenic patients]. Psychiatr Pol. 2008;42(1):87-95.
Konarzewska, B., Szulc, A., Popławska, R., Galińska, B., & Juchnowicz, D. (2008). [Impact of neuroleptic-induced hyperprolactinemia on sexual dysfunction in male schizophrenic patients]. Psychiatria Polska, 42(1), 87-95.
Konarzewska B, et al. [Impact of Neuroleptic-induced Hyperprolactinemia On Sexual Dysfunction in Male Schizophrenic Patients]. Psychiatr Pol. 2008 Jan-Feb;42(1):87-95. PubMed PMID: 18567406.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Impact of neuroleptic-induced hyperprolactinemia on sexual dysfunction in male schizophrenic patients]. AU - Konarzewska,Beata, AU - Szulc,Agata, AU - Popławska,Regina, AU - Galińska,Beata, AU - Juchnowicz,Dariusz, PY - 2008/6/24/pubmed PY - 2008/7/11/medline PY - 2008/6/24/entrez SP - 87 EP - 95 JF - Psychiatria polska JO - Psychiatr Pol VL - 42 IS - 1 N2 - Human sexual function is complex and effected in many different ways by schizophrenia and the antipsychotic drugs used in its treatment. Although not extensively researched, sexual dysfunction seems to be frequent in patients with schizophrenia, especially in men. They appear, in significant part, to be a direct consequence of dopamine antagonism, combined with indirect effects due to increased serum prolactin (PRL) concentration. All of the typical antipsychotics and risperidone can cause substantial PRL elevation. Hyperprolactinemia in male schizophrenics might decrease libido, cause anorgasmia and lead to erectile dysfunction. These sexual side effects are closely associated with the patients' willingness to take antipsychotics, and can affect compliance. SN - 0033-2674 UR - https://www.unboundmedicine.com/medline/citation/18567406/[Impact_of_neuroleptic_induced_hyperprolactinemia_on_sexual_dysfunction_in_male_schizophrenic_patients]_ L2 - http://www.diseaseinfosearch.org/result/2971 DB - PRIME DP - Unbound Medicine ER -