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Comparative study of the antibacterial activity of propolis from different geographical and climatic zones.

Abstract

Propolis is a natural substance produced by honeybees upon collection and transformation of resins and exudates from plants. Comparative studies on propolis collected from a wide range of countries are crucial for linking its provenance to antibacterial activity and thus ensuring that the beneficial properties of propolis are used more efficiently by the general public. This study reports the in vitro screening of ethanol extracts of propolis (n = 40), collected from a wide range of countries within the tropical, subtropical and temperate zones, and on the comparison of their activity against a range of Gram-positive and Gram-negative bacteria using a broth microdilution assay. The results obtained revealed that propolis extracts were mostly active against Gram-positive bacteria. The samples were subjected to principal component analysis (PCA) in order to model their activity against Gram-positive microorganisms. Three distinct clusters were distinguished in the PCA mapping based on MIC values, categorizing samples with strong (MIC range 3.9-31.25 mg/L), moderate (MIC range 31.25-> or =500 mg/L) and weak antibacterial activity or inactivity (MIC > or = 500 mg/L only). It is hypothesized that for samples of tropical provenance differences in the activity profiles may depend on the climatic characteristics of the collection sites. High antibacterial activity was observed for samples from locations characterized by a wet-tropical rainforest-type climate.

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  • Authors+Show Affiliations

    ,

    Natural Products Research Laboratories, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, UK.

    , ,

    Source

    Phytotherapy research : PTR 22:9 2008 Sep pg 1256-63

    MeSH

    Anti-Bacterial Agents
    Climate
    Drug Evaluation, Preclinical
    Geography
    Microbial Sensitivity Tests
    Propolis

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    18570199

    Citation

    Seidel, Véronique, et al. "Comparative Study of the Antibacterial Activity of Propolis From Different Geographical and Climatic Zones." Phytotherapy Research : PTR, vol. 22, no. 9, 2008, pp. 1256-63.
    Seidel V, Peyfoon E, Watson DG, et al. Comparative study of the antibacterial activity of propolis from different geographical and climatic zones. Phytother Res. 2008;22(9):1256-63.
    Seidel, V., Peyfoon, E., Watson, D. G., & Fearnley, J. (2008). Comparative study of the antibacterial activity of propolis from different geographical and climatic zones. Phytotherapy Research : PTR, 22(9), pp. 1256-63. doi:10.1002/ptr.2480.
    Seidel V, et al. Comparative Study of the Antibacterial Activity of Propolis From Different Geographical and Climatic Zones. Phytother Res. 2008;22(9):1256-63. PubMed PMID: 18570199.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Comparative study of the antibacterial activity of propolis from different geographical and climatic zones. AU - Seidel,Véronique, AU - Peyfoon,Elham, AU - Watson,David G, AU - Fearnley,James, PY - 2008/6/24/pubmed PY - 2008/12/19/medline PY - 2008/6/24/entrez SP - 1256 EP - 63 JF - Phytotherapy research : PTR JO - Phytother Res VL - 22 IS - 9 N2 - Propolis is a natural substance produced by honeybees upon collection and transformation of resins and exudates from plants. Comparative studies on propolis collected from a wide range of countries are crucial for linking its provenance to antibacterial activity and thus ensuring that the beneficial properties of propolis are used more efficiently by the general public. This study reports the in vitro screening of ethanol extracts of propolis (n = 40), collected from a wide range of countries within the tropical, subtropical and temperate zones, and on the comparison of their activity against a range of Gram-positive and Gram-negative bacteria using a broth microdilution assay. The results obtained revealed that propolis extracts were mostly active against Gram-positive bacteria. The samples were subjected to principal component analysis (PCA) in order to model their activity against Gram-positive microorganisms. Three distinct clusters were distinguished in the PCA mapping based on MIC values, categorizing samples with strong (MIC range 3.9-31.25 mg/L), moderate (MIC range 31.25-> or =500 mg/L) and weak antibacterial activity or inactivity (MIC > or = 500 mg/L only). It is hypothesized that for samples of tropical provenance differences in the activity profiles may depend on the climatic characteristics of the collection sites. High antibacterial activity was observed for samples from locations characterized by a wet-tropical rainforest-type climate. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/18570199/Comparative_study_of_the_antibacterial_activity_of_propolis_from_different_geographical_and_climatic_zones_ L2 - https://doi.org/10.1002/ptr.2480 DB - PRIME DP - Unbound Medicine ER -