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Long-term treatment with finasteride 1 mg decreases the likelihood of developing further visible hair loss in men with androgenetic alopecia (male pattern hair loss).
Eur J Dermatol. 2008 Jul-Aug; 18(4):400-6.EJ

Abstract

There are no reports on the effects of pharmacologic treatment on the likelihood of developing further visible hair loss in men with androgenetic alopecia (AGA). Our objectives were to examine whether finasteride 1 mg treatment decreases the likelihood of developing further visible hair loss in men with AGA. We conducted an analysis of global photographic assessment data from two Phase III trials in which 1553 men with AGA received finasteride 1 mg/day or placebo for up to 5 years. Finasteride 1 mg treatment led to a 93% decrease relative to placebo in the 5-year likelihood of developing further visible hair loss (95% CI: 89-97%; p < 0.001). We conclude that, in men with AGA, treatment with finasteride 1 mg/day over 5 years led to a marked and sustained decrease in the likelihood of developing further visible hair loss.

Authors+Show Affiliations

Merck Research Laboratories, Rahway, NJ 07065, USA. keith_kaufman@merck.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial, Phase III
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18573712

Citation

Kaufman, Keith D., et al. "Long-term Treatment With Finasteride 1 Mg Decreases the Likelihood of Developing Further Visible Hair Loss in Men With Androgenetic Alopecia (male Pattern Hair Loss)." European Journal of Dermatology : EJD, vol. 18, no. 4, 2008, pp. 400-6.
Kaufman KD, Rotonda J, Shah AK, et al. Long-term treatment with finasteride 1 mg decreases the likelihood of developing further visible hair loss in men with androgenetic alopecia (male pattern hair loss). Eur J Dermatol. 2008;18(4):400-6.
Kaufman, K. D., Rotonda, J., Shah, A. K., & Meehan, A. G. (2008). Long-term treatment with finasteride 1 mg decreases the likelihood of developing further visible hair loss in men with androgenetic alopecia (male pattern hair loss). European Journal of Dermatology : EJD, 18(4), 400-6. https://doi.org/10.1684/ejd.2008.0436
Kaufman KD, et al. Long-term Treatment With Finasteride 1 Mg Decreases the Likelihood of Developing Further Visible Hair Loss in Men With Androgenetic Alopecia (male Pattern Hair Loss). Eur J Dermatol. 2008 Jul-Aug;18(4):400-6. PubMed PMID: 18573712.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term treatment with finasteride 1 mg decreases the likelihood of developing further visible hair loss in men with androgenetic alopecia (male pattern hair loss). AU - Kaufman,Keith D, AU - Rotonda,Jennifer, AU - Shah,Arvind K, AU - Meehan,Alan G, Y1 - 2008/06/23/ PY - 2008/02/13/accepted PY - 2008/6/25/pubmed PY - 2008/12/17/medline PY - 2008/6/25/entrez SP - 400 EP - 6 JF - European journal of dermatology : EJD JO - Eur J Dermatol VL - 18 IS - 4 N2 - There are no reports on the effects of pharmacologic treatment on the likelihood of developing further visible hair loss in men with androgenetic alopecia (AGA). Our objectives were to examine whether finasteride 1 mg treatment decreases the likelihood of developing further visible hair loss in men with AGA. We conducted an analysis of global photographic assessment data from two Phase III trials in which 1553 men with AGA received finasteride 1 mg/day or placebo for up to 5 years. Finasteride 1 mg treatment led to a 93% decrease relative to placebo in the 5-year likelihood of developing further visible hair loss (95% CI: 89-97%; p < 0.001). We conclude that, in men with AGA, treatment with finasteride 1 mg/day over 5 years led to a marked and sustained decrease in the likelihood of developing further visible hair loss. SN - 1167-1122 UR - https://www.unboundmedicine.com/medline/citation/18573712/Long_term_treatment_with_finasteride_1_mg_decreases_the_likelihood_of_developing_further_visible_hair_loss_in_men_with_androgenetic_alopecia__male_pattern_hair_loss__ L2 - http://www.diseaseinfosearch.org/result/440 DB - PRIME DP - Unbound Medicine ER -