Tags

Type your tag names separated by a space and hit enter

Depressive symptoms during pregnancy in relation to fish consumption and intake of n-3 polyunsaturated fatty acids.
Paediatr Perinat Epidemiol. 2008 Jul; 22(4):389-99.PP

Abstract

An inverse association between depression and the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), primarily obtained from fish consumption, is observed in both observational and experimental research and is biologically plausible. Study objectives were to examine whether prenatal depressive symptoms were associated with lower intakes of fish or EPA+DHA. Pregnant women (n = 2394) completed a telephone interview between 10 and 22 weeks' gestation in London, Ontario, 2002-05. Depressive symptoms were measured using the Center for Epidemiologic Studies - Depression Scale (CES-D). Intakes of fish and EPA+DHA were measured using a validated food-frequency questionnaire. Sequential multiple regression was used to examine associations of depressive symptoms with intake of fish and EPA+DHA, respectively, while controlling for sociodemographic, health and lifestyle variables. The mean CES-D score was 9.9 (SD 8.0). Intake of EPA+DHA was dichotomised at the median value of 85 mg/day. Fish consumption and intake of EPA+DHA were not associated with prenatal depressive symptoms after adjustment for confounders; however, depressive symptoms were significantly higher for lower intakes of EPA+DHA among current smokers and women of single/separated/divorced marital status. The adjusted difference in CES-D scores between intake categories of EPA+DHA was -2.4 [95% CI -4.2, -0.4] for current smokers and -2.8 [95% CI -5.2, -0.4] for women of single marital status. Although pregnant women may be at risk for low concentrations of EPA and DHA, an association between low intakes of EPA+DHA and increased depressive symptoms was only observed among current smokers and women of single marital status.

Authors+Show Affiliations

Department of Epidemiology and Biostatistics, The University of Western Ontario, London, ON, Canada. jsontrop@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18578753

Citation

Sontrop, Jessica, et al. "Depressive Symptoms During Pregnancy in Relation to Fish Consumption and Intake of N-3 Polyunsaturated Fatty Acids." Paediatric and Perinatal Epidemiology, vol. 22, no. 4, 2008, pp. 389-99.
Sontrop J, Avison WR, Evers SE, et al. Depressive symptoms during pregnancy in relation to fish consumption and intake of n-3 polyunsaturated fatty acids. Paediatr Perinat Epidemiol. 2008;22(4):389-99.
Sontrop, J., Avison, W. R., Evers, S. E., Speechley, K. N., & Campbell, M. K. (2008). Depressive symptoms during pregnancy in relation to fish consumption and intake of n-3 polyunsaturated fatty acids. Paediatric and Perinatal Epidemiology, 22(4), 389-99. https://doi.org/10.1111/j.1365-3016.2008.00941.x
Sontrop J, et al. Depressive Symptoms During Pregnancy in Relation to Fish Consumption and Intake of N-3 Polyunsaturated Fatty Acids. Paediatr Perinat Epidemiol. 2008;22(4):389-99. PubMed PMID: 18578753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Depressive symptoms during pregnancy in relation to fish consumption and intake of n-3 polyunsaturated fatty acids. AU - Sontrop,Jessica, AU - Avison,William R, AU - Evers,Susan E, AU - Speechley,Kathy N, AU - Campbell,M Karen, PY - 2008/6/27/pubmed PY - 2008/11/11/medline PY - 2008/6/27/entrez SP - 389 EP - 99 JF - Paediatric and perinatal epidemiology JO - Paediatr Perinat Epidemiol VL - 22 IS - 4 N2 - An inverse association between depression and the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), primarily obtained from fish consumption, is observed in both observational and experimental research and is biologically plausible. Study objectives were to examine whether prenatal depressive symptoms were associated with lower intakes of fish or EPA+DHA. Pregnant women (n = 2394) completed a telephone interview between 10 and 22 weeks' gestation in London, Ontario, 2002-05. Depressive symptoms were measured using the Center for Epidemiologic Studies - Depression Scale (CES-D). Intakes of fish and EPA+DHA were measured using a validated food-frequency questionnaire. Sequential multiple regression was used to examine associations of depressive symptoms with intake of fish and EPA+DHA, respectively, while controlling for sociodemographic, health and lifestyle variables. The mean CES-D score was 9.9 (SD 8.0). Intake of EPA+DHA was dichotomised at the median value of 85 mg/day. Fish consumption and intake of EPA+DHA were not associated with prenatal depressive symptoms after adjustment for confounders; however, depressive symptoms were significantly higher for lower intakes of EPA+DHA among current smokers and women of single/separated/divorced marital status. The adjusted difference in CES-D scores between intake categories of EPA+DHA was -2.4 [95% CI -4.2, -0.4] for current smokers and -2.8 [95% CI -5.2, -0.4] for women of single marital status. Although pregnant women may be at risk for low concentrations of EPA and DHA, an association between low intakes of EPA+DHA and increased depressive symptoms was only observed among current smokers and women of single marital status. SN - 1365-3016 UR - https://www.unboundmedicine.com/medline/citation/18578753/Depressive_symptoms_during_pregnancy_in_relation_to_fish_consumption_and_intake_of_n_3_polyunsaturated_fatty_acids_ L2 - https://doi.org/10.1111/j.1365-3016.2008.00941.x DB - PRIME DP - Unbound Medicine ER -