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[Hydrogen sulfide (H2S), an endogenous gas with odor of rotten eggs might be a cardiovascular function regulator].
Ann Cardiol Angeiol (Paris). 2008 Jun; 57(3):136-8.AC

Abstract

A novel concept of "gasotransmitter" arrived recently. They are small molecules of endogenous gases. Hydrogene sulfide (H2S) is qualified as the third gasotransmitter beside nitric oxide (NO) and carbon monoxide (CO). The physiological functions of endogenous H2S are not well-known. The location of the H2S synthetizing enzymes as well as the detector of endogenous levels of H2S in the tissues suggests that the cardiovascular system is a source of H2S generation. This gas relaxes vascular smooth muscle both in vitro and in vivo probably by opening smooth K+ATP channels. Being a reducing agent, H2S may alter cellular redox status. It is able to produce thiyls free radicals: SH degrees and S degrees . The advances in H2S researchs may revolutionize many conventional doctrines in the cardiovascular area.

Authors+Show Affiliations

LPPCE, facultés de médecine et pharmacie, 7, boulevard Jeanne-d'Arc, 21033 Dijon, France. Luc.rochette@u-bourgogne.frNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

fre

PubMed ID

18579114

Citation

Rochette, L, and C Vergely. "[Hydrogen Sulfide (H2S), an Endogenous Gas With Odor of Rotten Eggs Might Be a Cardiovascular Function Regulator]." Annales De Cardiologie Et D'angeiologie, vol. 57, no. 3, 2008, pp. 136-8.
Rochette L, Vergely C. [Hydrogen sulfide (H2S), an endogenous gas with odor of rotten eggs might be a cardiovascular function regulator]. Ann Cardiol Angeiol (Paris). 2008;57(3):136-8.
Rochette, L., & Vergely, C. (2008). [Hydrogen sulfide (H2S), an endogenous gas with odor of rotten eggs might be a cardiovascular function regulator]. Annales De Cardiologie Et D'angeiologie, 57(3), 136-8. https://doi.org/10.1016/j.ancard.2008.02.014
Rochette L, Vergely C. [Hydrogen Sulfide (H2S), an Endogenous Gas With Odor of Rotten Eggs Might Be a Cardiovascular Function Regulator]. Ann Cardiol Angeiol (Paris). 2008;57(3):136-8. PubMed PMID: 18579114.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hydrogen sulfide (H2S), an endogenous gas with odor of rotten eggs might be a cardiovascular function regulator]. AU - Rochette,L, AU - Vergely,C, Y1 - 2008/06/04/ PY - 2008/02/20/received PY - 2008/02/28/accepted PY - 2008/6/27/pubmed PY - 2008/10/24/medline PY - 2008/6/27/entrez SP - 136 EP - 8 JF - Annales de cardiologie et d'angeiologie JO - Ann Cardiol Angeiol (Paris) VL - 57 IS - 3 N2 - A novel concept of "gasotransmitter" arrived recently. They are small molecules of endogenous gases. Hydrogene sulfide (H2S) is qualified as the third gasotransmitter beside nitric oxide (NO) and carbon monoxide (CO). The physiological functions of endogenous H2S are not well-known. The location of the H2S synthetizing enzymes as well as the detector of endogenous levels of H2S in the tissues suggests that the cardiovascular system is a source of H2S generation. This gas relaxes vascular smooth muscle both in vitro and in vivo probably by opening smooth K+ATP channels. Being a reducing agent, H2S may alter cellular redox status. It is able to produce thiyls free radicals: SH degrees and S degrees . The advances in H2S researchs may revolutionize many conventional doctrines in the cardiovascular area. SN - 0003-3928 UR - https://www.unboundmedicine.com/medline/citation/18579114/[Hydrogen_sulfide__H2S__an_endogenous_gas_with_odor_of_rotten_eggs_might_be_a_cardiovascular_function_regulator]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(08)00062-0 DB - PRIME DP - Unbound Medicine ER -