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Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis.
Indian J Ophthalmol. 2008 Jul-Aug; 56(4):338-40.IJ

Abstract

Chronic suppurative lacrimal canaliculitis is an important cause of ocular surface discomfort. Treatment with topical antibiotics is often inadequate and surgical treatment by canaliculotomy and canalicular curettage has been the mainstay of treatment in the past. The role of canalicular antibiotic irrigation has been inadequately studied. We report the clinical features, microbiological profile and treatment outcome in a series of 12 patients with suppurative lacrimal canaliculitis. Two patients had Actinomyces infection, five had Nocardia infection and seven patients had polymicrobial infection. Three patients had resolution of canaliculitis on combination broad-spectrum topical antibiotic therapy using ciprofloxacin and fortified cefazolin. In nine patients, topical antibiotic therapy was combined with canalicular irrigation using fortified cefazolin. All patients had excellent resolution of canaliculitis without the need for surgical treatment. Availability of broad-spectrum antibiotics and canalicular irrigation may offer an alternative to surgery in the management of suppurative lacrimal canaliculitis.

Authors+Show Affiliations

Medical and Vision Research Foundation, Chennai, Tamil Nadu, India. drerm@snmail.orgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18580001

Citation

Mohan, E Ravindra, et al. "Intracanalicular Antibiotics May Obviate the Need for Surgical Management of Chronic Suppurative Canaliculitis." Indian Journal of Ophthalmology, vol. 56, no. 4, 2008, pp. 338-40.
Mohan ER, Kabra S, Udhay P, et al. Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis. Indian J Ophthalmol. 2008;56(4):338-40.
Mohan, E. R., Kabra, S., Udhay, P., & Madhavan, H. N. (2008). Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis. Indian Journal of Ophthalmology, 56(4), 338-40.
Mohan ER, et al. Intracanalicular Antibiotics May Obviate the Need for Surgical Management of Chronic Suppurative Canaliculitis. Indian J Ophthalmol. 2008 Jul-Aug;56(4):338-40. PubMed PMID: 18580001.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis. AU - Mohan,E Ravindra, AU - Kabra,Sachin, AU - Udhay,Priti, AU - Madhavan,H N, PY - 2008/6/27/pubmed PY - 2008/11/5/medline PY - 2008/6/27/entrez SP - 338 EP - 40 JF - Indian journal of ophthalmology JO - Indian J Ophthalmol VL - 56 IS - 4 N2 - Chronic suppurative lacrimal canaliculitis is an important cause of ocular surface discomfort. Treatment with topical antibiotics is often inadequate and surgical treatment by canaliculotomy and canalicular curettage has been the mainstay of treatment in the past. The role of canalicular antibiotic irrigation has been inadequately studied. We report the clinical features, microbiological profile and treatment outcome in a series of 12 patients with suppurative lacrimal canaliculitis. Two patients had Actinomyces infection, five had Nocardia infection and seven patients had polymicrobial infection. Three patients had resolution of canaliculitis on combination broad-spectrum topical antibiotic therapy using ciprofloxacin and fortified cefazolin. In nine patients, topical antibiotic therapy was combined with canalicular irrigation using fortified cefazolin. All patients had excellent resolution of canaliculitis without the need for surgical treatment. Availability of broad-spectrum antibiotics and canalicular irrigation may offer an alternative to surgery in the management of suppurative lacrimal canaliculitis. SN - 0301-4738 UR - https://www.unboundmedicine.com/medline/citation/18580001/Intracanalicular_antibiotics_may_obviate_the_need_for_surgical_management_of_chronic_suppurative_canaliculitis_ L2 - http://www.ijo.in/article.asp?issn=0301-4738;year=2008;volume=56;issue=4;spage=338;epage=340;aulast=Mohan DB - PRIME DP - Unbound Medicine ER -