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Renal replacement therapy in acute kidney injury: which method to use in the intensive care unit?
Saudi J Kidney Dis Transpl. 2008 Jul; 19(4):529-36.SJ

Abstract

Over the last three decades the treatment options for patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT) have expanded from basic acute peritoneal dialysis and intermittent hemodialysis (IHD), to now include a variety of continuous modalities (CRRT), ranging from hemofiltration, dialysis and/or hemodiafiltration, and a variety of hybrid therapies, variously described as extended daily dialysis and/or hemodiafiltration, with the possibility of additional adjunct therapies encompassing plasma separation and adsorption techniques. Current evidence does not support that one modality is superior to any other in terms of patients' survival in the intensive care unit, or at discharge. There have been two prospective audits, which have reported improved renal recovery in the survivors who were treated by CRRT rather than IHD, but this has not been confirmed in randomized controlled trials. Thus the choice of RRT modality should be guided by the individual patients' clinical status, the medical and nursing expertise in the local intensive care unit, and the availability of RRT modality.

Authors

No affiliation info available

Pub Type(s)

Editorial

Language

eng

PubMed ID

18580008

Citation

Davenport, Andrew. "Renal Replacement Therapy in Acute Kidney Injury: Which Method to Use in the Intensive Care Unit?" Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia, vol. 19, no. 4, 2008, pp. 529-36.
Davenport A. Renal replacement therapy in acute kidney injury: which method to use in the intensive care unit? Saudi J Kidney Dis Transpl. 2008;19(4):529-36.
Davenport, A. (2008). Renal replacement therapy in acute kidney injury: which method to use in the intensive care unit? Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 19(4), 529-36.
Davenport A. Renal Replacement Therapy in Acute Kidney Injury: Which Method to Use in the Intensive Care Unit. Saudi J Kidney Dis Transpl. 2008;19(4):529-36. PubMed PMID: 18580008.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Renal replacement therapy in acute kidney injury: which method to use in the intensive care unit? A1 - Davenport,Andrew, PY - 2008/6/27/pubmed PY - 2008/11/8/medline PY - 2008/6/27/entrez SP - 529 EP - 36 JF - Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia JO - Saudi J Kidney Dis Transpl VL - 19 IS - 4 N2 - Over the last three decades the treatment options for patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT) have expanded from basic acute peritoneal dialysis and intermittent hemodialysis (IHD), to now include a variety of continuous modalities (CRRT), ranging from hemofiltration, dialysis and/or hemodiafiltration, and a variety of hybrid therapies, variously described as extended daily dialysis and/or hemodiafiltration, with the possibility of additional adjunct therapies encompassing plasma separation and adsorption techniques. Current evidence does not support that one modality is superior to any other in terms of patients' survival in the intensive care unit, or at discharge. There have been two prospective audits, which have reported improved renal recovery in the survivors who were treated by CRRT rather than IHD, but this has not been confirmed in randomized controlled trials. Thus the choice of RRT modality should be guided by the individual patients' clinical status, the medical and nursing expertise in the local intensive care unit, and the availability of RRT modality. SN - 1319-2442 UR - https://www.unboundmedicine.com/medline/citation/18580008/Renal_replacement_therapy_in_acute_kidney_injury:_which_method_to_use_in_the_intensive_care_unit L2 - http://www.sjkdt.org/article.asp?issn=1319-2442;year=2008;volume=19;issue=4;spage=529;epage=536;aulast=Davenport DB - PRIME DP - Unbound Medicine ER -