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Effect of opium addiction on diabetes.
Am J Drug Alcohol Abuse. 2008; 34(4):383-8.AJ

Abstract

BACKGROUND

Type 2 diabetes is a common disorder that is recognized as a major health problem in Iran. Diabetes is a major cause of morbidity, mortality, and economic burden to the society. Some people believe that smoking opium can reduce serum glucose and lipids in diabetes mellitus. This study was designed to compare blood glucose and lipids in opium addicts with non-addicts among patients with type 2 diabetes.

METHODS

In this case, control study subjects were chosen from type 2 diabetic patients. Twenty-three males with type 2 diabetes and addicted to opium were selected as the case group, and 46 patients with no addiction to opioid drugs were chosen as control group. Blood Sugar (BS), glycated hemoglobin (HbA1C), lipids and microalbumin in urine were measured in two groups.

RESULTS

Our results showed that the mean FBS and 2-hour post prandial were significantly different between two groups. (P = .04). No significant difference was observed in HbA1C, triglyceride, total cholesterol, LDL, and HDL between the two groups (P > .05).

CONCLUSIONS

Our finding showed that while opium might decrease blood glucose temporarily, it had no clear and long-lasting effects on blood glucose, as it had no significant effect on HbA1c.

Authors+Show Affiliations

Yazd Diabetes Research Center, Shahid Sadougdi University of Medical Science, Yazd, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18584567

Citation

Azod, Laila, et al. "Effect of Opium Addiction On Diabetes." The American Journal of Drug and Alcohol Abuse, vol. 34, no. 4, 2008, pp. 383-8.
Azod L, Rashidi M, Afkhami-Ardekani M, et al. Effect of opium addiction on diabetes. Am J Drug Alcohol Abuse. 2008;34(4):383-8.
Azod, L., Rashidi, M., Afkhami-Ardekani, M., Kiani, G., & Khoshkam, F. (2008). Effect of opium addiction on diabetes. The American Journal of Drug and Alcohol Abuse, 34(4), 383-8. https://doi.org/10.1080/00952990802122580
Azod L, et al. Effect of Opium Addiction On Diabetes. Am J Drug Alcohol Abuse. 2008;34(4):383-8. PubMed PMID: 18584567.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of opium addiction on diabetes. AU - Azod,Laila, AU - Rashidi,Maryam, AU - Afkhami-Ardekani,Mohammad, AU - Kiani,Golchehr, AU - Khoshkam,Fariba, PY - 2008/6/28/pubmed PY - 2008/8/15/medline PY - 2008/6/28/entrez SP - 383 EP - 8 JF - The American journal of drug and alcohol abuse JO - Am J Drug Alcohol Abuse VL - 34 IS - 4 N2 - BACKGROUND: Type 2 diabetes is a common disorder that is recognized as a major health problem in Iran. Diabetes is a major cause of morbidity, mortality, and economic burden to the society. Some people believe that smoking opium can reduce serum glucose and lipids in diabetes mellitus. This study was designed to compare blood glucose and lipids in opium addicts with non-addicts among patients with type 2 diabetes. METHODS: In this case, control study subjects were chosen from type 2 diabetic patients. Twenty-three males with type 2 diabetes and addicted to opium were selected as the case group, and 46 patients with no addiction to opioid drugs were chosen as control group. Blood Sugar (BS), glycated hemoglobin (HbA1C), lipids and microalbumin in urine were measured in two groups. RESULTS: Our results showed that the mean FBS and 2-hour post prandial were significantly different between two groups. (P = .04). No significant difference was observed in HbA1C, triglyceride, total cholesterol, LDL, and HDL between the two groups (P > .05). CONCLUSIONS: Our finding showed that while opium might decrease blood glucose temporarily, it had no clear and long-lasting effects on blood glucose, as it had no significant effect on HbA1c. SN - 1097-9891 UR - https://www.unboundmedicine.com/medline/citation/18584567/Effect_of_opium_addiction_on_diabetes_ L2 - https://www.tandfonline.com/doi/full/10.1080/00952990802122580 DB - PRIME DP - Unbound Medicine ER -