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Crohn's colitis complicated by superimposed invasive amebic colitis.
Am J Gastroenterol. 1991 Aug; 86(8):1063-5.AJ

Abstract

The clinical characteristics and endoscopic appearance of inflammatory bowel disease (IBD) may be very similar to those of amebic colitis. Physicians, especially in areas in which amebiasis is endemic, are familiar with this difficulty. Moreover, in individual cases, it may even be impossible to distinguish between the two conditions, since stool specimens, bowel biopsies, and serological studies may be negative for Entamoeba histolytica, even in the presence of invasive amebic colitis. Invasive amebiasis may rarely be superimposed on IBD, which further complicates the issue. We report here a young patient with a 7-yr history of Crohn's colitis proven histologically who developed invasive amebic colitis during steroid and 6-mercaptopurine treatment for active disease. Stool specimens, mucosal biopsies, and serological studies were negative for E. histolytica, and the diagnosis was established on pathological examination of a surgically resected bowel. Anti-amebic therapy should be considered in endemic areas in cases of persistent IBD.

Authors+Show Affiliations

Department of Gastroenterology, Hadassah University Hospital, Jerusalem, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

1858742

Citation

Lysy, J, et al. "Crohn's Colitis Complicated By Superimposed Invasive Amebic Colitis." The American Journal of Gastroenterology, vol. 86, no. 8, 1991, pp. 1063-5.
Lysy J, Zimmerman J, Sherman Y, et al. Crohn's colitis complicated by superimposed invasive amebic colitis. Am J Gastroenterol. 1991;86(8):1063-5.
Lysy, J., Zimmerman, J., Sherman, Y., Feigin, R., & Ligumsky, M. (1991). Crohn's colitis complicated by superimposed invasive amebic colitis. The American Journal of Gastroenterology, 86(8), 1063-5.
Lysy J, et al. Crohn's Colitis Complicated By Superimposed Invasive Amebic Colitis. Am J Gastroenterol. 1991;86(8):1063-5. PubMed PMID: 1858742.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Crohn's colitis complicated by superimposed invasive amebic colitis. AU - Lysy,J, AU - Zimmerman,J, AU - Sherman,Y, AU - Feigin,R, AU - Ligumsky,M, PY - 1991/8/1/pubmed PY - 1991/8/1/medline PY - 1991/8/1/entrez SP - 1063 EP - 5 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 86 IS - 8 N2 - The clinical characteristics and endoscopic appearance of inflammatory bowel disease (IBD) may be very similar to those of amebic colitis. Physicians, especially in areas in which amebiasis is endemic, are familiar with this difficulty. Moreover, in individual cases, it may even be impossible to distinguish between the two conditions, since stool specimens, bowel biopsies, and serological studies may be negative for Entamoeba histolytica, even in the presence of invasive amebic colitis. Invasive amebiasis may rarely be superimposed on IBD, which further complicates the issue. We report here a young patient with a 7-yr history of Crohn's colitis proven histologically who developed invasive amebic colitis during steroid and 6-mercaptopurine treatment for active disease. Stool specimens, mucosal biopsies, and serological studies were negative for E. histolytica, and the diagnosis was established on pathological examination of a surgically resected bowel. Anti-amebic therapy should be considered in endemic areas in cases of persistent IBD. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/1858742/Crohn's_colitis_complicated_by_superimposed_invasive_amebic_colitis_ L2 - https://medlineplus.gov/crohnsdisease.html DB - PRIME DP - Unbound Medicine ER -