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Update on irritable bowel syndrome and gender differences.
Nutr Clin Pract. 2008 Jun-Jul; 23(3):275-83.NC

Abstract

Irritable bowel syndrome (IBS) is a chronic functional GI disorder characterized by abdominal pain associated with alterations in defecation or stool frequency and consistency. In Western industrialized countries, women seek health care services for their symptoms more frequently than men. The cause of IBS is likely multifactorial involving altered motility, visceral hypersensitivity, and dysregulation of the autonomic nervous system. Many patients note that their symptoms are exacerbated by diet and stress, and women frequently report menstrual cycle fluctuations in symptoms. Current approaches to IBS management include behavioral management therapies such as dietary intake changes and stress reduction cognitive restructuring. Drug therapies are targeted at altering pain sensitivity, motility, and secretion. This review provides an overview of the pathogenesis of IBS, factors that contribute to gender differences, and current therapeutic approaches for symptom management.

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Authors+Show Affiliations

Heitkemper MM
Department of Biobehavioral Nursing, University of Washington, Seattle, WA 98195, USA. heit@u.washington.edu
Jarrett ME
No affiliation info available

MeSH

Abdominal PainAutonomic Nervous SystemDietFemaleGastrointestinal MotilityHumansIrritable Bowel SyndromeMaleMenstrual CycleProbioticsSerotoninSex FactorsStress, Psychological

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

18595860

Citation

Heitkemper, Margaret M., and Monica E. Jarrett. "Update On Irritable Bowel Syndrome and Gender Differences." Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition, vol. 23, no. 3, 2008, pp. 275-83.
Heitkemper MM, Jarrett ME. Update on irritable bowel syndrome and gender differences. Nutr Clin Pract. 2008;23(3):275-83.
Heitkemper, M. M., & Jarrett, M. E. (2008). Update on irritable bowel syndrome and gender differences. Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition, 23(3), 275-83. https://doi.org/10.1177/0884533608318672
Heitkemper MM, Jarrett ME. Update On Irritable Bowel Syndrome and Gender Differences. Nutr Clin Pract. 2008 Jun-Jul;23(3):275-83. PubMed PMID: 18595860.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Update on irritable bowel syndrome and gender differences. AU - Heitkemper,Margaret M, AU - Jarrett,Monica E, PY - 2008/7/4/pubmed PY - 2008/10/10/medline PY - 2008/7/4/entrez SP - 275 EP - 83 JF - Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition JO - Nutr Clin Pract VL - 23 IS - 3 N2 - Irritable bowel syndrome (IBS) is a chronic functional GI disorder characterized by abdominal pain associated with alterations in defecation or stool frequency and consistency. In Western industrialized countries, women seek health care services for their symptoms more frequently than men. The cause of IBS is likely multifactorial involving altered motility, visceral hypersensitivity, and dysregulation of the autonomic nervous system. Many patients note that their symptoms are exacerbated by diet and stress, and women frequently report menstrual cycle fluctuations in symptoms. Current approaches to IBS management include behavioral management therapies such as dietary intake changes and stress reduction cognitive restructuring. Drug therapies are targeted at altering pain sensitivity, motility, and secretion. This review provides an overview of the pathogenesis of IBS, factors that contribute to gender differences, and current therapeutic approaches for symptom management. SN - 0884-5336 UR - https://www.unboundmedicine.com/medline/citation/18595860/Update_on_irritable_bowel_syndrome_and_gender_differences_ L2 - https://doi.org/10.1177/0884533608318672 DB - PRIME DP - Unbound Medicine ER -