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Coronary lesion type, location, and characteristics of acute ST elevation myocardial infarction in young adults under 35 years of age.
Coron Artery Dis. 2008 Aug; 19(5):345-7.CA

Abstract

OBJECTIVE

In the present study, we attempted to analyze the coronary artery lesion characteristics of acute ST elevation myocardial infarction (STEMI) in young patients (aged less than 35 years).

METHODS

We retrospectively surveyed 25 038 coronary angiography procedures, which were carried out at The Baskent University Adana Hospital from 1998 to present, to discover acute STEMI in young patients. We studied clinical risk factors and angiographic characteristics in 42 consecutive patients who underwent primary coronary angiography for acute STEMI. Control group (n=42) had no history of coronary artery disease and had angiographically proven normal coronary arteries. All patients were under 35 years of age. Angiographic features for STEMI group were collected and both groups were compared for coronary risk factors.

RESULTS

Male sex was more prevalent in acute STEMI group when compared with control participants (83 vs. 59%, respectively; P=0.01). A significant difference was found in cigarette smoking (62 vs. 36%, respectively; P=0.007) and family history (33 vs. 16%, respectively; P=0.03) between the two groups. No statistical significance was observed between the groups in terms of hypertension, diabetes mellitus, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels. Mean high-density lipoprotein cholesterol level was 33+/-8 mg/dl in STEMI group and 39+/-12 mg/dl in control participants (P=0.02). Young patients with acute STEMI showed a preponderance of single-vessel disease (69%) and acute anterior STEMI (60%) owing to occluded left anterior descending artery (P<0.001).

CONCLUSION

We observed risk factors such as family history, smoking, and low high-density lipoprotein cholesterol levels in young adults. Acute anterior STEMI owing to occluded left anterior descending artery was more frequent. Coronary atherosclerosis was characterized by higher presence of type B and proximal lesions. The handling selection was percutaneous coronary intervention in more than half of the patients.

Authors+Show Affiliations

Department of Cardiology, Faculty of Medicine, Baskent University, Ankara, Turkey. kardiyoloji@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18607172

Citation

Colkesen, Abdurrahman Yucel, et al. "Coronary Lesion Type, Location, and Characteristics of Acute ST Elevation Myocardial Infarction in Young Adults Under 35 Years of Age." Coronary Artery Disease, vol. 19, no. 5, 2008, pp. 345-7.
Colkesen AY, Acil T, Demircan S, et al. Coronary lesion type, location, and characteristics of acute ST elevation myocardial infarction in young adults under 35 years of age. Coron Artery Dis. 2008;19(5):345-7.
Colkesen, A. Y., Acil, T., Demircan, S., Sezgin, A. T., & Muderrisoglu, H. (2008). Coronary lesion type, location, and characteristics of acute ST elevation myocardial infarction in young adults under 35 years of age. Coronary Artery Disease, 19(5), 345-7. https://doi.org/10.1097/MCA.0b013e3283030b3b
Colkesen AY, et al. Coronary Lesion Type, Location, and Characteristics of Acute ST Elevation Myocardial Infarction in Young Adults Under 35 Years of Age. Coron Artery Dis. 2008;19(5):345-7. PubMed PMID: 18607172.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coronary lesion type, location, and characteristics of acute ST elevation myocardial infarction in young adults under 35 years of age. AU - Colkesen,Abdurrahman Yucel, AU - Acil,Tayfun, AU - Demircan,Senol, AU - Sezgin,Alpay T, AU - Muderrisoglu,Haldun, PY - 2008/7/9/pubmed PY - 2008/12/17/medline PY - 2008/7/9/entrez SP - 345 EP - 7 JF - Coronary artery disease JO - Coron Artery Dis VL - 19 IS - 5 N2 - OBJECTIVE: In the present study, we attempted to analyze the coronary artery lesion characteristics of acute ST elevation myocardial infarction (STEMI) in young patients (aged less than 35 years). METHODS: We retrospectively surveyed 25 038 coronary angiography procedures, which were carried out at The Baskent University Adana Hospital from 1998 to present, to discover acute STEMI in young patients. We studied clinical risk factors and angiographic characteristics in 42 consecutive patients who underwent primary coronary angiography for acute STEMI. Control group (n=42) had no history of coronary artery disease and had angiographically proven normal coronary arteries. All patients were under 35 years of age. Angiographic features for STEMI group were collected and both groups were compared for coronary risk factors. RESULTS: Male sex was more prevalent in acute STEMI group when compared with control participants (83 vs. 59%, respectively; P=0.01). A significant difference was found in cigarette smoking (62 vs. 36%, respectively; P=0.007) and family history (33 vs. 16%, respectively; P=0.03) between the two groups. No statistical significance was observed between the groups in terms of hypertension, diabetes mellitus, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels. Mean high-density lipoprotein cholesterol level was 33+/-8 mg/dl in STEMI group and 39+/-12 mg/dl in control participants (P=0.02). Young patients with acute STEMI showed a preponderance of single-vessel disease (69%) and acute anterior STEMI (60%) owing to occluded left anterior descending artery (P<0.001). CONCLUSION: We observed risk factors such as family history, smoking, and low high-density lipoprotein cholesterol levels in young adults. Acute anterior STEMI owing to occluded left anterior descending artery was more frequent. Coronary atherosclerosis was characterized by higher presence of type B and proximal lesions. The handling selection was percutaneous coronary intervention in more than half of the patients. SN - 0954-6928 UR - https://www.unboundmedicine.com/medline/citation/18607172/Coronary_lesion_type_location_and_characteristics_of_acute_ST_elevation_myocardial_infarction_in_young_adults_under_35_years_of_age_ L2 - https://doi.org/10.1097/MCA.0b013e3283030b3b DB - PRIME DP - Unbound Medicine ER -