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[A novel nano-hydroxyapatite/aliphatic polyesteramide composite].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2008; 25(2):378-81, 392SW

Abstract

Hydrothermally synthesized nano-hydroxyapatite (n-HA) varying in weight from 10% to 30% was used as filler to make nanocomposites with novel aliphatic polyesteramide (PEA) in our laboratory. The structure and properties of PEA and its n-HA composites were investigated through transmission electron microscopy, infrared spectrometry, X-ray diffractioin, scanning electron microscopy and energy spectrometry. The shape and size of the n-HA crystals are similar to those of the apatite crystals in natural bone. Molecule interactions are present between the n-HA and PEA in the composite, which allows the uniform dispersion of n-HA in PEA matrix. This contributes enhanced mechanical property and bioactivity to the composite. The cytocompatibility of the composites has been investigated by culturing osteoblasts on the membranes. Good cell attachment and proliferation manner were observed on the membranes after 1 week. These results suggest that the PEA/n-HA composites prepared in this study may serve as potential candidate scaffold for tissue engineering.

Authors+Show Affiliations

West China College of Stomatology, Sichuan University, Chengdu 610041, China. xiad520@sina.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

18610626

Citation

Deng, Xia, et al. "[A Novel Nano-hydroxyapatite/aliphatic Polyesteramide Composite]." Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi, vol. 25, no. 2, 2008, pp. 378-81, 392.
Deng X, Chen Z, Qian Z, et al. [A novel nano-hydroxyapatite/aliphatic polyesteramide composite]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2008;25(2):378-81, 392.
Deng, X., Chen, Z., Qian, Z., Liu, C., & Li, H. (2008). [A novel nano-hydroxyapatite/aliphatic polyesteramide composite]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi, 25(2), pp. 378-81, 392.
Deng X, et al. [A Novel Nano-hydroxyapatite/aliphatic Polyesteramide Composite]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2008;25(2):378-81, 392. PubMed PMID: 18610626.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A novel nano-hydroxyapatite/aliphatic polyesteramide composite]. AU - Deng,Xia, AU - Chen,Zhiqing, AU - Qian,Zhiyong, AU - Liu,Caibing, AU - Li,Hong, PY - 2008/7/10/pubmed PY - 2009/6/24/medline PY - 2008/7/10/entrez SP - 378-81, 392 JF - Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi JO - Sheng Wu Yi Xue Gong Cheng Xue Za Zhi VL - 25 IS - 2 N2 - Hydrothermally synthesized nano-hydroxyapatite (n-HA) varying in weight from 10% to 30% was used as filler to make nanocomposites with novel aliphatic polyesteramide (PEA) in our laboratory. The structure and properties of PEA and its n-HA composites were investigated through transmission electron microscopy, infrared spectrometry, X-ray diffractioin, scanning electron microscopy and energy spectrometry. The shape and size of the n-HA crystals are similar to those of the apatite crystals in natural bone. Molecule interactions are present between the n-HA and PEA in the composite, which allows the uniform dispersion of n-HA in PEA matrix. This contributes enhanced mechanical property and bioactivity to the composite. The cytocompatibility of the composites has been investigated by culturing osteoblasts on the membranes. Good cell attachment and proliferation manner were observed on the membranes after 1 week. These results suggest that the PEA/n-HA composites prepared in this study may serve as potential candidate scaffold for tissue engineering. SN - 1001-5515 UR - https://www.unboundmedicine.com/medline/citation/18610626/[A_novel_nano_hydroxyapatite/aliphatic_polyesteramide_composite]_ DB - PRIME DP - Unbound Medicine ER -