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Anorectal manometry in patients with chronic constipation: a single-center experience.
Hepatogastroenterology. 2008 Mar-Apr; 55(82-83):426-9.H

Abstract

BACKGROUND/AIMS

Constipation is a common complaint, but its clinical presentation varies with each individual. The aim of this study was to evaluate anorectal physiology in a prospective group of patients with chronic constipation.

METHODOLOGY

A total of 24 consecutive patients with constipation underwent solid-state anorectal manometry. Fifteen healthy controls were also studied. The anorectal parameters included resting and squeeze sphincter pressure, sensory thresholds in response to balloon distension, compliance of rectum, and rectoanal inhibitory reflex (RAIR).

RESULTS

The rectal sensitivity for urge and pain did not differ between the groups, but the threshold volume for first sensation was higher in patients with constipation (p < 0.05). There was no group difference in the volume threshold for RAIR. However, the prevalence of impaired RAIR was higher in constipated patients. Anal pressure was lower in patients for maximal squeeze (p < 0.05). There was a positive correlation between the anal sphincter length and resting pressure in patients (r = 0.51, p = 0.03) and healthy controls (r = 0.72, p = 0.01).

CONCLUSIONS

Constipated patients are characterized by impaired rectal sensitivity and decreased anal sphincter contractile pressure. Anorectal manometry is helpful for diagnosing anorectal dysfunction in patients with chronic constipation.

Authors+Show Affiliations

Liu TT
Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan.
Chen CL
No affiliation info available
Yi CH
No affiliation info available

MeSH

AdultAgedAged, 80 and overAnal CanalChronic DiseaseConstipationFemaleHumansMaleManometryMiddle AgedProspective StudiesRectum

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18613380

Citation

Liu, Tso-Tsai, et al. "Anorectal Manometry in Patients With Chronic Constipation: a Single-center Experience." Hepato-gastroenterology, vol. 55, no. 82-83, 2008, pp. 426-9.
Liu TT, Chen CL, Yi CH. Anorectal manometry in patients with chronic constipation: a single-center experience. Hepatogastroenterology. 2008;55(82-83):426-9.
Liu, T. T., Chen, C. L., & Yi, C. H. (2008). Anorectal manometry in patients with chronic constipation: a single-center experience. Hepato-gastroenterology, 55(82-83), 426-9.
Liu TT, Chen CL, Yi CH. Anorectal Manometry in Patients With Chronic Constipation: a Single-center Experience. Hepatogastroenterology. 2008 Mar-Apr;55(82-83):426-9. PubMed PMID: 18613380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anorectal manometry in patients with chronic constipation: a single-center experience. AU - Liu,Tso-Tsai, AU - Chen,Chien-Lin, AU - Yi,Chih-Hsun, PY - 2008/7/11/pubmed PY - 2008/12/17/medline PY - 2008/7/11/entrez SP - 426 EP - 9 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 55 IS - 82-83 N2 - BACKGROUND/AIMS: Constipation is a common complaint, but its clinical presentation varies with each individual. The aim of this study was to evaluate anorectal physiology in a prospective group of patients with chronic constipation. METHODOLOGY: A total of 24 consecutive patients with constipation underwent solid-state anorectal manometry. Fifteen healthy controls were also studied. The anorectal parameters included resting and squeeze sphincter pressure, sensory thresholds in response to balloon distension, compliance of rectum, and rectoanal inhibitory reflex (RAIR). RESULTS: The rectal sensitivity for urge and pain did not differ between the groups, but the threshold volume for first sensation was higher in patients with constipation (p < 0.05). There was no group difference in the volume threshold for RAIR. However, the prevalence of impaired RAIR was higher in constipated patients. Anal pressure was lower in patients for maximal squeeze (p < 0.05). There was a positive correlation between the anal sphincter length and resting pressure in patients (r = 0.51, p = 0.03) and healthy controls (r = 0.72, p = 0.01). CONCLUSIONS: Constipated patients are characterized by impaired rectal sensitivity and decreased anal sphincter contractile pressure. Anorectal manometry is helpful for diagnosing anorectal dysfunction in patients with chronic constipation. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/18613380/Anorectal_manometry_in_patients_with_chronic_constipation:_a_single_center_experience_ L2 - http://www.diseaseinfosearch.org/result/1885 DB - PRIME DP - Unbound Medicine ER -