Tags

Type your tag names separated by a space and hit enter

Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis.
J Diabetes Complications. 2009 Nov-Dec; 23(6):434-7.JD

Abstract

A 27-year-old male, who had developed diabetes mellitus type 1 (DMT1) since the age of eighteen and alopecia areata universalis nine months later, attended the outpatient clinics complaining of general fatigue and shortness of breath. A Schilling test was indicative of pernicious anemia. Antigastric parietal cell (AGPA) and anti-intrinsic factor antibodies were positive, confirming diagnosis of pernicious anemia. Thyroid and Addison's disease were excluded. Gastroscopy revealed atrophic gastritis without any evidence of carcinoid tumors. The aim of this case, which, to our knowledge, is the first one to describe a correlation between diabetes mellitus Type 1 (DMT1), pernicious anaemia, and alopecia areata universalis, is to remind the clinician of the increased risk of pernicious anaemia and gastric carcinoids in DMT1 patients. Screening for AGPA followed by serum gastrin and vitamin B(12) levels constitute the most evidence-based diagnostic approach.

Authors+Show Affiliations

Department of Internal Medicine, Mamatseio General Hospital, Kozani, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18614380

Citation

Tzellos, Thrasivoulos G., et al. "Pernicious Anemia in a Patient With Type 1 Diabetes Mellitus and Alopecia Areata Universalis." Journal of Diabetes and Its Complications, vol. 23, no. 6, 2009, pp. 434-7.
Tzellos TG, Tahmatzidis DK, Lallas A, et al. Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis. J Diabetes Complications. 2009;23(6):434-7.
Tzellos, T. G., Tahmatzidis, D. K., Lallas, A., Apostolidou, K., & Goulis, D. G. (2009). Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis. Journal of Diabetes and Its Complications, 23(6), 434-7. https://doi.org/10.1016/j.jdiacomp.2008.05.003
Tzellos TG, et al. Pernicious Anemia in a Patient With Type 1 Diabetes Mellitus and Alopecia Areata Universalis. J Diabetes Complications. 2009 Nov-Dec;23(6):434-7. PubMed PMID: 18614380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pernicious anemia in a patient with Type 1 diabetes mellitus and alopecia areata universalis. AU - Tzellos,Thrasivoulos G, AU - Tahmatzidis,Dimitrios K, AU - Lallas,Aimilios, AU - Apostolidou,Kiriaki, AU - Goulis,Dimitrios G, Y1 - 2008/07/09/ PY - 2008/03/14/received PY - 2008/05/08/accepted PY - 2008/7/11/pubmed PY - 2010/1/26/medline PY - 2008/7/11/entrez SP - 434 EP - 7 JF - Journal of diabetes and its complications JO - J Diabetes Complications VL - 23 IS - 6 N2 - A 27-year-old male, who had developed diabetes mellitus type 1 (DMT1) since the age of eighteen and alopecia areata universalis nine months later, attended the outpatient clinics complaining of general fatigue and shortness of breath. A Schilling test was indicative of pernicious anemia. Antigastric parietal cell (AGPA) and anti-intrinsic factor antibodies were positive, confirming diagnosis of pernicious anemia. Thyroid and Addison's disease were excluded. Gastroscopy revealed atrophic gastritis without any evidence of carcinoid tumors. The aim of this case, which, to our knowledge, is the first one to describe a correlation between diabetes mellitus Type 1 (DMT1), pernicious anaemia, and alopecia areata universalis, is to remind the clinician of the increased risk of pernicious anaemia and gastric carcinoids in DMT1 patients. Screening for AGPA followed by serum gastrin and vitamin B(12) levels constitute the most evidence-based diagnostic approach. SN - 1873-460X UR - https://www.unboundmedicine.com/medline/citation/18614380/Pernicious_anemia_in_a_patient_with_Type_1_diabetes_mellitus_and_alopecia_areata_universalis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1056-8727(08)00052-4 DB - PRIME DP - Unbound Medicine ER -