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New MCR-Heck-isomerization cascade toward indoles.
Org Lett. 2008 Aug 21; 10(16):3417-9.OL

Abstract

The use of ortho-iodonitrophenol in Ugi-Smiles reaction coupled with Heck cyclization gives new access to indole scaffolds. The sequence can be performed in a one-pot reaction if the residual isocyanide is neutralized prior to the addition of the palladium catalyst.

Authors+Show Affiliations

Laboratoire Chimie et Procédés, Ecole Nationale Supérieure de Techniques Avancées, 32 Bd Victor, 75739 Paris Cedex 15, France. laurent.elkaim@ensta.frNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18616343

Citation

El Kaim, Laurent, et al. "New MCR-Heck-isomerization Cascade Toward Indoles." Organic Letters, vol. 10, no. 16, 2008, pp. 3417-9.
El Kaim L, Gizzi M, Grimaud L. New MCR-Heck-isomerization cascade toward indoles. Org Lett. 2008;10(16):3417-9.
El Kaim, L., Gizzi, M., & Grimaud, L. (2008). New MCR-Heck-isomerization cascade toward indoles. Organic Letters, 10(16), 3417-9. https://doi.org/10.1021/ol801217a
El Kaim L, Gizzi M, Grimaud L. New MCR-Heck-isomerization Cascade Toward Indoles. Org Lett. 2008 Aug 21;10(16):3417-9. PubMed PMID: 18616343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New MCR-Heck-isomerization cascade toward indoles. AU - El Kaim,Laurent, AU - Gizzi,Marion, AU - Grimaud,Laurence, Y1 - 2008/07/11/ PY - 2008/7/12/pubmed PY - 2008/10/22/medline PY - 2008/7/12/entrez SP - 3417 EP - 9 JF - Organic letters JO - Org Lett VL - 10 IS - 16 N2 - The use of ortho-iodonitrophenol in Ugi-Smiles reaction coupled with Heck cyclization gives new access to indole scaffolds. The sequence can be performed in a one-pot reaction if the residual isocyanide is neutralized prior to the addition of the palladium catalyst. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/18616343/New_MCR_Heck_isomerization_cascade_toward_indoles_ L2 - https://doi.org/10.1021/ol801217a DB - PRIME DP - Unbound Medicine ER -