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Diagnostic properties of a symptoms scale for diagnosing reflux esophagitis.
J Clin Epidemiol. 2009 Jan; 62(1):97-101.JC

Abstract

OBJECTIVE

To the objective of the study was to determine accuracy and predictive values of a symptoms scale for diagnosing reflux esophagitis (RE).

STUDY DESIGN AND SETTING

Standard criterion study. All recruited patients from two centers in Chile underwent both digestive endoscopy (reference standard) and a symptoms scale known to be valid and reliable for diagnosing gastroesophageal reflux disease. The RE variable was dealt with dichotomously. A receiver operating characteristic curve was constructed. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios of the scale were calculated.

RESULTS

Two hundred and thirty eight (238) subjects (57.6% female), with an average age of 44.2+/-13.0 years were included. Of these, 57.1% presented with RE. With a cut-off score of six, association was confirmed between the symptoms scale and RE with an odds ratio of 7.26 and a correct classification i.e. diagnostic accuracy of 73.1%. Sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios, of 74.3%, 71.6%, 77.7%, 67.6%, 2.61, and 0.36 respectively, were obtained.

CONCLUSION

A seven-item symptoms scale when compared to endoscopy as gold standard was useful for diagnosing RE. Using a cutoff of six points, the diagnostic accuracy of the scale was 73.1%.

Authors+Show Affiliations

Department of Anatomy, Faculty of Medicine, Universidad de Concepción, Chile.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

18619802

Citation

Torres-Quevedo, Rodrigo, et al. "Diagnostic Properties of a Symptoms Scale for Diagnosing Reflux Esophagitis." Journal of Clinical Epidemiology, vol. 62, no. 1, 2009, pp. 97-101.
Torres-Quevedo R, Manterola C, Sanhueza A, et al. Diagnostic properties of a symptoms scale for diagnosing reflux esophagitis. J Clin Epidemiol. 2009;62(1):97-101.
Torres-Quevedo, R., Manterola, C., Sanhueza, A., Bustos, L., Pineda, V., & Vial, M. (2009). Diagnostic properties of a symptoms scale for diagnosing reflux esophagitis. Journal of Clinical Epidemiology, 62(1), 97-101. https://doi.org/10.1016/j.jclinepi.2008.03.001
Torres-Quevedo R, et al. Diagnostic Properties of a Symptoms Scale for Diagnosing Reflux Esophagitis. J Clin Epidemiol. 2009;62(1):97-101. PubMed PMID: 18619802.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic properties of a symptoms scale for diagnosing reflux esophagitis. AU - Torres-Quevedo,Rodrigo, AU - Manterola,Carlos, AU - Sanhueza,Antonio, AU - Bustos,Luis, AU - Pineda,Viviana, AU - Vial,Manuel, Y1 - 2008/07/10/ PY - 2006/12/28/received PY - 2008/01/13/revised PY - 2008/03/10/accepted PY - 2008/7/16/pubmed PY - 2009/4/3/medline PY - 2008/7/16/entrez SP - 97 EP - 101 JF - Journal of clinical epidemiology JO - J Clin Epidemiol VL - 62 IS - 1 N2 - OBJECTIVE: To the objective of the study was to determine accuracy and predictive values of a symptoms scale for diagnosing reflux esophagitis (RE). STUDY DESIGN AND SETTING: Standard criterion study. All recruited patients from two centers in Chile underwent both digestive endoscopy (reference standard) and a symptoms scale known to be valid and reliable for diagnosing gastroesophageal reflux disease. The RE variable was dealt with dichotomously. A receiver operating characteristic curve was constructed. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios of the scale were calculated. RESULTS: Two hundred and thirty eight (238) subjects (57.6% female), with an average age of 44.2+/-13.0 years were included. Of these, 57.1% presented with RE. With a cut-off score of six, association was confirmed between the symptoms scale and RE with an odds ratio of 7.26 and a correct classification i.e. diagnostic accuracy of 73.1%. Sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios, of 74.3%, 71.6%, 77.7%, 67.6%, 2.61, and 0.36 respectively, were obtained. CONCLUSION: A seven-item symptoms scale when compared to endoscopy as gold standard was useful for diagnosing RE. Using a cutoff of six points, the diagnostic accuracy of the scale was 73.1%. SN - 1878-5921 UR - https://www.unboundmedicine.com/medline/citation/18619802/Diagnostic_properties_of_a_symptoms_scale_for_diagnosing_reflux_esophagitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0895-4356(08)00065-6 DB - PRIME DP - Unbound Medicine ER -