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Contrast-enhanced T1-weighted fluid-attenuated inversion-recovery BLADE magnetic resonance imaging of the brain: an alternative to spin-echo technique for detection of brain lesions in the unsedated pediatric patient?
Acad Radiol. 2008 Aug; 15(8):986-95.AR

Abstract

RATIONALE AND OBJECTIVES

We compared contrast-enhanced T1-weighted magnetic resonance (MR) imaging of the brain using different types of data acquisition techniques: periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER, BLADE) imaging versus standard k-space sampling (conventional spin-echo pulse sequence) in the unsedated pediatric patient with focus on artifact reduction, overall image quality, and lesion detectability.

MATERIALS AND METHODS

Forty-eight pediatric patients (aged 3 months to 18 years) were scanned with a clinical 1.5-T whole body MR scanner. Cross-sectional contrast-enhanced T1-weighted spin-echo sequence was compared to a T1-weighted dark-fluid fluid-attenuated inversion-recovery (FLAIR) BLADE sequence for qualitative and quantitative criteria (image artifacts, image quality, lesion detectability) by two experienced radiologists. Imaging protocols were matched for imaging parameters. Reader agreement was assessed using the exact Bowker test.

RESULTS

BLADE images showed significantly less pulsation and motion artifacts than the standard T1-weighted spin-echo sequence scan. BLADE images showed statistically significant lower signal-to-noise ratio but higher contrast-to-noise ratios with superior gray-white matter contrast. All lesions were demonstrated on FLAIR BLADE imaging, and one false-positive lesion was visible in spin-echo sequence images.

CONCLUSION

BLADE MR imaging at 1.5 T is applicable for central nervous system imaging of the unsedated pediatric patient, reduces motion and pulsation artifacts, and minimizes the need for sedation or general anesthesia without loss of relevant diagnostic information.

Authors+Show Affiliations

Institute of Radiology, University of Erlangen, Maximiliansplatz 1, 91054 Erlangen/Germany. sedat.alibek@uk-erlangen.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

18620119

Citation

Alibek, Sedat, et al. "Contrast-enhanced T1-weighted Fluid-attenuated Inversion-recovery BLADE Magnetic Resonance Imaging of the Brain: an Alternative to Spin-echo Technique for Detection of Brain Lesions in the Unsedated Pediatric Patient?" Academic Radiology, vol. 15, no. 8, 2008, pp. 986-95.
Alibek S, Adamietz B, Cavallaro A, et al. Contrast-enhanced T1-weighted fluid-attenuated inversion-recovery BLADE magnetic resonance imaging of the brain: an alternative to spin-echo technique for detection of brain lesions in the unsedated pediatric patient? Acad Radiol. 2008;15(8):986-95.
Alibek, S., Adamietz, B., Cavallaro, A., Stemmer, A., Anders, K., Kramer, M., Bautz, W., & Staatz, G. (2008). Contrast-enhanced T1-weighted fluid-attenuated inversion-recovery BLADE magnetic resonance imaging of the brain: an alternative to spin-echo technique for detection of brain lesions in the unsedated pediatric patient? Academic Radiology, 15(8), 986-95. https://doi.org/10.1016/j.acra.2008.03.009
Alibek S, et al. Contrast-enhanced T1-weighted Fluid-attenuated Inversion-recovery BLADE Magnetic Resonance Imaging of the Brain: an Alternative to Spin-echo Technique for Detection of Brain Lesions in the Unsedated Pediatric Patient. Acad Radiol. 2008;15(8):986-95. PubMed PMID: 18620119.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Contrast-enhanced T1-weighted fluid-attenuated inversion-recovery BLADE magnetic resonance imaging of the brain: an alternative to spin-echo technique for detection of brain lesions in the unsedated pediatric patient? AU - Alibek,Sedat, AU - Adamietz,Boris, AU - Cavallaro,Alexander, AU - Stemmer,Alto, AU - Anders,Katharina, AU - Kramer,Manuel, AU - Bautz,Werner, AU - Staatz,Gundula, PY - 2007/12/17/received PY - 2008/02/20/revised PY - 2008/02/20/accepted PY - 2008/7/16/pubmed PY - 2008/12/18/medline PY - 2008/7/16/entrez SP - 986 EP - 95 JF - Academic radiology JO - Acad Radiol VL - 15 IS - 8 N2 - RATIONALE AND OBJECTIVES: We compared contrast-enhanced T1-weighted magnetic resonance (MR) imaging of the brain using different types of data acquisition techniques: periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER, BLADE) imaging versus standard k-space sampling (conventional spin-echo pulse sequence) in the unsedated pediatric patient with focus on artifact reduction, overall image quality, and lesion detectability. MATERIALS AND METHODS: Forty-eight pediatric patients (aged 3 months to 18 years) were scanned with a clinical 1.5-T whole body MR scanner. Cross-sectional contrast-enhanced T1-weighted spin-echo sequence was compared to a T1-weighted dark-fluid fluid-attenuated inversion-recovery (FLAIR) BLADE sequence for qualitative and quantitative criteria (image artifacts, image quality, lesion detectability) by two experienced radiologists. Imaging protocols were matched for imaging parameters. Reader agreement was assessed using the exact Bowker test. RESULTS: BLADE images showed significantly less pulsation and motion artifacts than the standard T1-weighted spin-echo sequence scan. BLADE images showed statistically significant lower signal-to-noise ratio but higher contrast-to-noise ratios with superior gray-white matter contrast. All lesions were demonstrated on FLAIR BLADE imaging, and one false-positive lesion was visible in spin-echo sequence images. CONCLUSION: BLADE MR imaging at 1.5 T is applicable for central nervous system imaging of the unsedated pediatric patient, reduces motion and pulsation artifacts, and minimizes the need for sedation or general anesthesia without loss of relevant diagnostic information. SN - 1076-6332 UR - https://www.unboundmedicine.com/medline/citation/18620119/Contrast_enhanced_T1_weighted_fluid_attenuated_inversion_recovery_BLADE_magnetic_resonance_imaging_of_the_brain:_an_alternative_to_spin_echo_technique_for_detection_of_brain_lesions_in_the_unsedated_pediatric_patient L2 - https://linkinghub.elsevier.com/retrieve/pii/S1076-6332(08)00182-7 DB - PRIME DP - Unbound Medicine ER -