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Paraganglioma of the cauda equina. A case report and review of the literature.
Acta Pathol Jpn. 1991 Apr; 41(4):305-10.AP

Abstract

A case of paraganglioma of the cauda equina is reported. The patient was a 55-year-old Japanese woman who complained of lower back pain and gradual weakening of the left lower extremity, she was diagnosed as having a spinal cord tumor, and the tumor was removed surgically. Histologically, the tumor was encapsulated, and consisted of solid nests of large, polyhedral epithelioid cells with abundant eosinophilic cytoplasm. The nests were separated from each other by a thin fibrovascular stroma. Grimelius staining revealed neurosecretory granules in the cytoplasm of the tumor cells. This was further confirmed by electron microscopic observation. The tumor cells were immunohistochemically positive for neuron-specific enolase (NSE), but negative for glial fibrillary acidic protein (GFAP). On the basis of the histologic, immunohistochemical and electron microscopic features of the tumor cells, the tumor was diagnosed as paraganglioma. The cauda equina is a rare location for this type of tumor, and only a limited number of cases have been reported.

Authors+Show Affiliations

First Department of Pathology, Kagoshima, University Faculty of Medicine, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

1862709

Citation

Yoshida, A, et al. "Paraganglioma of the Cauda Equina. a Case Report and Review of the Literature." Acta Pathologica Japonica, vol. 41, no. 4, 1991, pp. 305-10.
Yoshida A, Umekita Y, Ohi Y, et al. Paraganglioma of the cauda equina. A case report and review of the literature. Acta Pathol Jpn. 1991;41(4):305-10.
Yoshida, A., Umekita, Y., Ohi, Y., Hatanaka, S., & Yoshida, H. (1991). Paraganglioma of the cauda equina. A case report and review of the literature. Acta Pathologica Japonica, 41(4), 305-10.
Yoshida A, et al. Paraganglioma of the Cauda Equina. a Case Report and Review of the Literature. Acta Pathol Jpn. 1991;41(4):305-10. PubMed PMID: 1862709.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paraganglioma of the cauda equina. A case report and review of the literature. AU - Yoshida,A, AU - Umekita,Y, AU - Ohi,Y, AU - Hatanaka,S, AU - Yoshida,H, PY - 1991/4/1/pubmed PY - 1991/4/1/medline PY - 1991/4/1/entrez SP - 305 EP - 10 JF - Acta pathologica japonica JO - Acta Pathol. Jpn. VL - 41 IS - 4 N2 - A case of paraganglioma of the cauda equina is reported. The patient was a 55-year-old Japanese woman who complained of lower back pain and gradual weakening of the left lower extremity, she was diagnosed as having a spinal cord tumor, and the tumor was removed surgically. Histologically, the tumor was encapsulated, and consisted of solid nests of large, polyhedral epithelioid cells with abundant eosinophilic cytoplasm. The nests were separated from each other by a thin fibrovascular stroma. Grimelius staining revealed neurosecretory granules in the cytoplasm of the tumor cells. This was further confirmed by electron microscopic observation. The tumor cells were immunohistochemically positive for neuron-specific enolase (NSE), but negative for glial fibrillary acidic protein (GFAP). On the basis of the histologic, immunohistochemical and electron microscopic features of the tumor cells, the tumor was diagnosed as paraganglioma. The cauda equina is a rare location for this type of tumor, and only a limited number of cases have been reported. SN - 0001-6632 UR - https://www.unboundmedicine.com/medline/citation/1862709/Paraganglioma_of_the_cauda_equina__A_case_report_and_review_of_the_literature_ DB - PRIME DP - Unbound Medicine ER -