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[Comparative study on Chinese medicine and western medicine for treatment of osteoarthritis of the knee in Caucasian patients].
Zhongguo Zhen Jiu 2008; 28(6):459-62ZZ

Abstract

OBJECTIVE

To compare the efficacy, safety and tolerability of different therapies in Caucasian patients with osteoarthritis (QA) of the knee.

METHODS

Seventy-five cases (90 knee joints) of osteoarthritis were randomly divided into 3 groups, western medicine group, traditional Chinese medicine (TCM) group, integrated Chinese and western medicine group. The western medicine group were treated with oral administration of Glucosamine Sulfate, oral administration and external application of non-steroid anti-inflammatory agent, ultrasound physiotherapy, etc. The TCM group were treated with oral administration of J uanbi Decoction, acupuncture and moxibustion, cupping, massage of acupoint and ear acupuncture. The integrated Chinese and western medicine group were treated with oral administration of Glucosamine Sulfate, oral administration and external application of non-steroid anti-inflammatory agent, acupuncture and moxibustion, cupping, massage of acupoint and ear acupuncture. The intensity of knee joint pain on walking, resting and standing, the nocturnal pain, stiffness, the maximum walking distance and the daily living ability were monitored after 30 days, 60 days and 90 days of treatment.

RESULTS

After 90 days of treatment, the integrated Chinese and western medicine group was better than other two groups in improvement of percentages in self pain assessment with visual analog scale (VAS), pain and stiffness measured by WOMAC scale, pain and maximum walking distance measured by Lequesne scale (P < 0.05 or P < 0.01). There were no significant differences in the therapeutic effects between the TCM group and the western medicine group. All of these three treatments were well tolerated, and no severe adverse events were found.

CONCLUSION

Combined TCM and western medicine treatment has rapid and definite therapeutic effect in reducing pain and improving mobility of knee joints and daily living ability in Caucasian patients of knee osteoarthritis.

Authors+Show Affiliations

Xuanwu Hospital, Capital Medical University, Beijing 100053, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

18630549

Citation

Qin, Xin-Yan, et al. "[Comparative Study On Chinese Medicine and Western Medicine for Treatment of Osteoarthritis of the Knee in Caucasian Patients]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 28, no. 6, 2008, pp. 459-62.
Qin XY, Li XX, Berghea F, et al. [Comparative study on Chinese medicine and western medicine for treatment of osteoarthritis of the knee in Caucasian patients]. Zhongguo Zhen Jiu. 2008;28(6):459-62.
Qin, X. Y., Li, X. X., Berghea, F., & Suteanu, S. (2008). [Comparative study on Chinese medicine and western medicine for treatment of osteoarthritis of the knee in Caucasian patients]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 28(6), pp. 459-62.
Qin XY, et al. [Comparative Study On Chinese Medicine and Western Medicine for Treatment of Osteoarthritis of the Knee in Caucasian Patients]. Zhongguo Zhen Jiu. 2008;28(6):459-62. PubMed PMID: 18630549.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Comparative study on Chinese medicine and western medicine for treatment of osteoarthritis of the knee in Caucasian patients]. AU - Qin,Xin-Yan, AU - Li,Xiao-Xia, AU - Berghea,Florian, AU - Suteanu,Stefan, PY - 2008/7/18/pubmed PY - 2008/7/30/medline PY - 2008/7/18/entrez SP - 459 EP - 62 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 28 IS - 6 N2 - OBJECTIVE: To compare the efficacy, safety and tolerability of different therapies in Caucasian patients with osteoarthritis (QA) of the knee. METHODS: Seventy-five cases (90 knee joints) of osteoarthritis were randomly divided into 3 groups, western medicine group, traditional Chinese medicine (TCM) group, integrated Chinese and western medicine group. The western medicine group were treated with oral administration of Glucosamine Sulfate, oral administration and external application of non-steroid anti-inflammatory agent, ultrasound physiotherapy, etc. The TCM group were treated with oral administration of J uanbi Decoction, acupuncture and moxibustion, cupping, massage of acupoint and ear acupuncture. The integrated Chinese and western medicine group were treated with oral administration of Glucosamine Sulfate, oral administration and external application of non-steroid anti-inflammatory agent, acupuncture and moxibustion, cupping, massage of acupoint and ear acupuncture. The intensity of knee joint pain on walking, resting and standing, the nocturnal pain, stiffness, the maximum walking distance and the daily living ability were monitored after 30 days, 60 days and 90 days of treatment. RESULTS: After 90 days of treatment, the integrated Chinese and western medicine group was better than other two groups in improvement of percentages in self pain assessment with visual analog scale (VAS), pain and stiffness measured by WOMAC scale, pain and maximum walking distance measured by Lequesne scale (P < 0.05 or P < 0.01). There were no significant differences in the therapeutic effects between the TCM group and the western medicine group. All of these three treatments were well tolerated, and no severe adverse events were found. CONCLUSION: Combined TCM and western medicine treatment has rapid and definite therapeutic effect in reducing pain and improving mobility of knee joints and daily living ability in Caucasian patients of knee osteoarthritis. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/18630549/[Comparative_study_on_Chinese_medicine_and_western_medicine_for_treatment_of_osteoarthritis_of_the_knee_in_Caucasian_patients]_ DB - PRIME DP - Unbound Medicine ER -