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[Effects of high-carbohydrate/low-fat diet on serum lipid ratios in healthy young subjects].
Sichuan Da Xue Xue Bao Yi Xue Ban 2008; 39(2):267-71, 275SD

Abstract

OBJECTIVE

To investigate the effects of the short-term high-carbohydrate/low-fat (HC/LF) diet on the serum lipid ratios of healthy young subjects, which meant triglyceride to high-density lipoprotein cholesterol (TG/HDL-C), the logarithm of TG/HDL-C [log (TG/HDL-C)], low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C), and total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C).

METHODS

56 healthy participants with the average age of (22.89 +/- 1.80) years took the normal diet for 7 days followed by HC/LF diet for 6 days. Venous blood samples in fasting were collected between 7 : 00 and 10 : 00 AM on the 1st, the 8th and 14th day, respectively. Serum concentrations of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) were measured by regular methods. The ratios of TG/HDL-C, log (TG/HDL-C), LDL-C/HDL-C, and TC/ HDL-C were calculated.

RESULTS

After HC/LF diet, both TG/HDL-C and log (TG/HDL-C) increased significantly for females (P < 0.05). For the males, these two ratios were decreased although not significant in statistics. When BMI or WHR was taken into account, the two ratios increased significantly after HC/LF diet, but only for the normal females (P < 0.05), not for the females with overall or abdominal adiposity. No significant changes of TG/HDL-C and log(TG/HDL-C) after HC/LF diet were observed between the males with different BMI or WHR. TC/HDL-C and LDL-C/HDL-C decreased significantly (P < 0.05) after HC/LF diet, but these changes were not found to associate with gender, BMI or WHR.

CONCLUSION

The changes of TG/HDL-C and log (TG/HDL-C) induced by the short-term HC/LF diet are different in healthy young subjects with different gender, BMI or WHR, but there is no significant change happening to TC/HDL-C and LDL-C/HDL-C.

Authors+Show Affiliations

Department of Biochemistry and Molecular Biology Laboratory, West China School of Preclinical and Forensic, Medicine, Sichuan University, Chengdu 610041, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

18630700

Citation

Gan, Chan-Fen, et al. "[Effects of High-carbohydrate/low-fat Diet On Serum Lipid Ratios in Healthy Young Subjects]." Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition, vol. 39, no. 2, 2008, pp. 267-71, 275.
Gan CF, Gong RR, Lin J, et al. [Effects of high-carbohydrate/low-fat diet on serum lipid ratios in healthy young subjects]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2008;39(2):267-71, 275.
Gan, C. F., Gong, R. R., Lin, J., Li, Z. K., Tang, H., Huang, X., ... Fang, D. Z. (2008). [Effects of high-carbohydrate/low-fat diet on serum lipid ratios in healthy young subjects]. Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition, 39(2), pp. 267-71, 275.
Gan CF, et al. [Effects of High-carbohydrate/low-fat Diet On Serum Lipid Ratios in Healthy Young Subjects]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2008;39(2):267-71, 275. PubMed PMID: 18630700.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effects of high-carbohydrate/low-fat diet on serum lipid ratios in healthy young subjects]. AU - Gan,Chan-Fen, AU - Gong,Ren-Rong, AU - Lin,Jia, AU - Li,Zheng-Ke, AU - Tang,Hui, AU - Huang,Xin, AU - Li,Rong-Hui, AU - Fang,Ding-Zhi, PY - 2008/7/18/pubmed PY - 2009/2/28/medline PY - 2008/7/18/entrez SP - 267-71, 275 JF - Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition JO - Sichuan Da Xue Xue Bao Yi Xue Ban VL - 39 IS - 2 N2 - OBJECTIVE: To investigate the effects of the short-term high-carbohydrate/low-fat (HC/LF) diet on the serum lipid ratios of healthy young subjects, which meant triglyceride to high-density lipoprotein cholesterol (TG/HDL-C), the logarithm of TG/HDL-C [log (TG/HDL-C)], low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C), and total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C). METHODS: 56 healthy participants with the average age of (22.89 +/- 1.80) years took the normal diet for 7 days followed by HC/LF diet for 6 days. Venous blood samples in fasting were collected between 7 : 00 and 10 : 00 AM on the 1st, the 8th and 14th day, respectively. Serum concentrations of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) were measured by regular methods. The ratios of TG/HDL-C, log (TG/HDL-C), LDL-C/HDL-C, and TC/ HDL-C were calculated. RESULTS: After HC/LF diet, both TG/HDL-C and log (TG/HDL-C) increased significantly for females (P < 0.05). For the males, these two ratios were decreased although not significant in statistics. When BMI or WHR was taken into account, the two ratios increased significantly after HC/LF diet, but only for the normal females (P < 0.05), not for the females with overall or abdominal adiposity. No significant changes of TG/HDL-C and log(TG/HDL-C) after HC/LF diet were observed between the males with different BMI or WHR. TC/HDL-C and LDL-C/HDL-C decreased significantly (P < 0.05) after HC/LF diet, but these changes were not found to associate with gender, BMI or WHR. CONCLUSION: The changes of TG/HDL-C and log (TG/HDL-C) induced by the short-term HC/LF diet are different in healthy young subjects with different gender, BMI or WHR, but there is no significant change happening to TC/HDL-C and LDL-C/HDL-C. SN - 1672-173X UR - https://www.unboundmedicine.com/medline/citation/18630700/[Effects_of_high_carbohydrate/low_fat_diet_on_serum_lipid_ratios_in_healthy_young_subjects]_ L2 - https://medlineplus.gov/dietaryfats.html DB - PRIME DP - Unbound Medicine ER -