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Concise total synthesis of (+)-crocacin C.
J Org Chem. 2008 Aug 15; 73(16):6386-8.JO

Abstract

The cytotoxic natural product (+)-crocacin C (1) has been synthesized in 10 linear steps from commercially available Evans' chiral propionimide in 5% overall yield (8 steps from Evans' chiral dipropionate synthon). No protecting groups were utilized.

Authors+Show Affiliations

Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18630880

Citation

Sirasani, Gopal, et al. "Concise Total Synthesis of (+)-crocacin C." The Journal of Organic Chemistry, vol. 73, no. 16, 2008, pp. 6386-8.
Sirasani G, Paul T, Andrade RB. Concise total synthesis of (+)-crocacin C. J Org Chem. 2008;73(16):6386-8.
Sirasani, G., Paul, T., & Andrade, R. B. (2008). Concise total synthesis of (+)-crocacin C. The Journal of Organic Chemistry, 73(16), 6386-8. https://doi.org/10.1021/jo800906p
Sirasani G, Paul T, Andrade RB. Concise Total Synthesis of (+)-crocacin C. J Org Chem. 2008 Aug 15;73(16):6386-8. PubMed PMID: 18630880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Concise total synthesis of (+)-crocacin C. AU - Sirasani,Gopal, AU - Paul,Tapas, AU - Andrade,Rodrigo B, Y1 - 2008/07/16/ PY - 2008/7/18/pubmed PY - 2008/10/23/medline PY - 2008/7/18/entrez SP - 6386 EP - 8 JF - The Journal of organic chemistry JO - J Org Chem VL - 73 IS - 16 N2 - The cytotoxic natural product (+)-crocacin C (1) has been synthesized in 10 linear steps from commercially available Evans' chiral propionimide in 5% overall yield (8 steps from Evans' chiral dipropionate synthon). No protecting groups were utilized. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/18630880/Concise_total_synthesis_of__+__crocacin_C_ L2 - https://doi.org/10.1021/jo800906p DB - PRIME DP - Unbound Medicine ER -
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