Concise total synthesis of (+)-crocacin C.J Org Chem. 2008 Aug 15; 73(16):6386-8.JO
Abstract
The cytotoxic natural product (+)-crocacin C (1) has been synthesized in 10 linear steps from commercially available Evans' chiral propionimide in 5% overall yield (8 steps from Evans' chiral dipropionate synthon). No protecting groups were utilized.
Links
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
18630880
Citation
Sirasani, Gopal, et al. "Concise Total Synthesis of (+)-crocacin C." The Journal of Organic Chemistry, vol. 73, no. 16, 2008, pp. 6386-8.
Sirasani G, Paul T, Andrade RB. Concise total synthesis of (+)-crocacin C. J Org Chem. 2008;73(16):6386-8.
Sirasani, G., Paul, T., & Andrade, R. B. (2008). Concise total synthesis of (+)-crocacin C. The Journal of Organic Chemistry, 73(16), 6386-8. https://doi.org/10.1021/jo800906p
Sirasani G, Paul T, Andrade RB. Concise Total Synthesis of (+)-crocacin C. J Org Chem. 2008 Aug 15;73(16):6386-8. PubMed PMID: 18630880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Concise total synthesis of (+)-crocacin C.
AU - Sirasani,Gopal,
AU - Paul,Tapas,
AU - Andrade,Rodrigo B,
Y1 - 2008/07/16/
PY - 2008/7/18/pubmed
PY - 2008/10/23/medline
PY - 2008/7/18/entrez
SP - 6386
EP - 8
JF - The Journal of organic chemistry
JO - J Org Chem
VL - 73
IS - 16
N2 - The cytotoxic natural product (+)-crocacin C (1) has been synthesized in 10 linear steps from commercially available Evans' chiral propionimide in 5% overall yield (8 steps from Evans' chiral dipropionate synthon). No protecting groups were utilized.
SN - 1520-6904
UR - https://www.unboundmedicine.com/medline/citation/18630880/Concise_total_synthesis_of__+__crocacin_C_
L2 - https://doi.org/10.1021/jo800906p
DB - PRIME
DP - Unbound Medicine
ER -