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An in vitro evaluation of the antimicrobial activity of nine root canal sealers.
J Contemp Dent Pract. 2008 Jul 01; 9(5):60-7.JC

Abstract

AIM

The purpose of this in vitro study was to analyze the antimicrobial activity of root canal sealers by using the agar diffusion test (ADT).

METHODS AND MATERIALS

Three categories of root canal sealers were included in the study: resin-based sealers (4), zinc oxide-based sealers (3), and calcium hydroxide-based sealers (2). The microbial strains used were: S. aureus (2 strains), C. albicans (2 strains), and E. faecalis (1 strain). Statistical analysis was conducted using a one-way analysis of variance (ANOVA). Tests of differences were analyzed using the Tukey's test with a value of p < 0.05 considered statistically significant.

RESULTS

The antimicrobial activity of root canal sealers was ranked in descending order as follows: Sealite Regular, Cortisemol, Dentalis KEZ, AH26, Sealapex, Acroseal/Topseal, and Endorez/AH plus.

CONCLUSION

Root canal sealers showed different inhibitory effects depending on their types and the bacterial strains tested. Root canal sealers containing formaldehyde and eugenol proved to be effective against the microorganisms studied.

CLINICAL SIGNIFICANCE

The incorporation of antimicrobial components into root canal sealers may become an essential factor in preventing the re-growth of residual bacteria and control of bacteria re-entry into the root canal system.

Authors+Show Affiliations

Department of Conservative Dentistry and Prosthodontics, Faculty of Dentistry, University of Jordan, Amman, Jordan. l.smadi@ju.edu.joNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

18633470

Citation

Smadi, Leena, et al. "An in Vitro Evaluation of the Antimicrobial Activity of Nine Root Canal Sealers." The Journal of Contemporary Dental Practice, vol. 9, no. 5, 2008, pp. 60-7.
Smadi L, Mahafzah A, Khraisat A. An in vitro evaluation of the antimicrobial activity of nine root canal sealers. J Contemp Dent Pract. 2008;9(5):60-7.
Smadi, L., Mahafzah, A., & Khraisat, A. (2008). An in vitro evaluation of the antimicrobial activity of nine root canal sealers. The Journal of Contemporary Dental Practice, 9(5), 60-7.
Smadi L, Mahafzah A, Khraisat A. An in Vitro Evaluation of the Antimicrobial Activity of Nine Root Canal Sealers. J Contemp Dent Pract. 2008 Jul 1;9(5):60-7. PubMed PMID: 18633470.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An in vitro evaluation of the antimicrobial activity of nine root canal sealers. AU - Smadi,Leena, AU - Mahafzah,Azmi, AU - Khraisat,Ameen, Y1 - 2008/07/01/ PY - 2008/7/18/pubmed PY - 2008/10/7/medline PY - 2008/7/18/entrez SP - 60 EP - 7 JF - The journal of contemporary dental practice JO - J Contemp Dent Pract VL - 9 IS - 5 N2 - AIM: The purpose of this in vitro study was to analyze the antimicrobial activity of root canal sealers by using the agar diffusion test (ADT). METHODS AND MATERIALS: Three categories of root canal sealers were included in the study: resin-based sealers (4), zinc oxide-based sealers (3), and calcium hydroxide-based sealers (2). The microbial strains used were: S. aureus (2 strains), C. albicans (2 strains), and E. faecalis (1 strain). Statistical analysis was conducted using a one-way analysis of variance (ANOVA). Tests of differences were analyzed using the Tukey's test with a value of p < 0.05 considered statistically significant. RESULTS: The antimicrobial activity of root canal sealers was ranked in descending order as follows: Sealite Regular, Cortisemol, Dentalis KEZ, AH26, Sealapex, Acroseal/Topseal, and Endorez/AH plus. CONCLUSION: Root canal sealers showed different inhibitory effects depending on their types and the bacterial strains tested. Root canal sealers containing formaldehyde and eugenol proved to be effective against the microorganisms studied. CLINICAL SIGNIFICANCE: The incorporation of antimicrobial components into root canal sealers may become an essential factor in preventing the re-growth of residual bacteria and control of bacteria re-entry into the root canal system. SN - 1526-3711 UR - https://www.unboundmedicine.com/medline/citation/18633470/An_in_vitro_evaluation_of_the_antimicrobial_activity_of_nine_root_canal_sealers_ DB - PRIME DP - Unbound Medicine ER -