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[Pharmacotherapy of central oculomotor disorders].
Nervenarzt. 2008 Dec; 79(12):1377-8, 1380-2, 1384-5.N

Abstract

Nystagmus causes blurred vision due to oscillopsia, as well as impaired balance. Depending on etiology, additional cerebellar and brain stem signs may occur. We present the current pharmacotherapy of the most common forms of central nystagmus: downbeat nystagmus (DBN), upbeat nystagmus (UBN), acquired pendular nystagmus (APN), and congenital nystagmus (CGN). Recommended medical therapies are aminopyridines (4-AP) for DBN and UBN, gabapentin and memantine for CGN and APN, and baclofen for periodic alternating nystagmus (PAN).

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Authors+Show Affiliations

Kalla R
Neurologische Klinik, Klinikum Grosshadern Ludwig-Maximilians-Universität (LMU) München, Marchioninistr. 15, 81377, München. Roger.Kalla@med.uni-muenchen.de
Spiegel R
No affiliation info available
Wagner J
No affiliation info available
Rettinger N
No affiliation info available
Jahn K
No affiliation info available
Strupp M
No affiliation info available

MeSH

4-AminopyridineAmifampridineAminesBaclofenCyclohexanecarboxylic AcidsDiagnosis, DifferentialDose-Response Relationship, DrugDrug Administration ScheduleGabapentinHumansMagnetic Resonance ImagingMemantineNystagmus, PathologicVestibular Nucleigamma-Aminobutyric Acid

Pub Type(s)

Journal Article
Review

Language

ger

PubMed ID

18633586

Citation

Kalla, R, et al. "[Pharmacotherapy of Central Oculomotor Disorders]." Der Nervenarzt, vol. 79, no. 12, 2008, pp. 1377-8, 1380-2, 1384-5.
Kalla R, Spiegel R, Wagner J, et al. [Pharmacotherapy of central oculomotor disorders]. Nervenarzt. 2008;79(12):1377-8, 1380-2, 1384-5.
Kalla, R., Spiegel, R., Wagner, J., Rettinger, N., Jahn, K., & Strupp, M. (2008). [Pharmacotherapy of central oculomotor disorders]. Der Nervenarzt, 79(12), 1377-8, 1380-2, 1384-5. https://doi.org/10.1007/s00115-008-2516-0
Kalla R, et al. [Pharmacotherapy of Central Oculomotor Disorders]. Nervenarzt. 2008;79(12):1377-8, 1380-2, 1384-5. PubMed PMID: 18633586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pharmacotherapy of central oculomotor disorders]. AU - Kalla,R, AU - Spiegel,R, AU - Wagner,J, AU - Rettinger,N, AU - Jahn,K, AU - Strupp,M, PY - 2008/7/18/pubmed PY - 2009/4/21/medline PY - 2008/7/18/entrez SP - 1377-8, 1380-2, 1384-5 JF - Der Nervenarzt JO - Nervenarzt VL - 79 IS - 12 N2 - Nystagmus causes blurred vision due to oscillopsia, as well as impaired balance. Depending on etiology, additional cerebellar and brain stem signs may occur. We present the current pharmacotherapy of the most common forms of central nystagmus: downbeat nystagmus (DBN), upbeat nystagmus (UBN), acquired pendular nystagmus (APN), and congenital nystagmus (CGN). Recommended medical therapies are aminopyridines (4-AP) for DBN and UBN, gabapentin and memantine for CGN and APN, and baclofen for periodic alternating nystagmus (PAN). SN - 0028-2804 UR - https://www.unboundmedicine.com/medline/citation/18633586/[Pharmacotherapy_of_central_oculomotor_disorders]_ L2 - https://dx.doi.org/10.1007/s00115-008-2516-0 DB - PRIME DP - Unbound Medicine ER -