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MR imaging-guided 10-gauge vacuum-assisted breast biopsy: histological characterisation.
Radiol Med. 2008 Sep; 113(6):830-40.RM

Abstract

PURPOSE

The aim of this study was to evaluate a handheld vacuum-assisted device for magnetic resonance imaging (MRI)-guided breast biopsy.

MATERIALS AND METHODS

In 47 patients, a total of 47 suspicious breast lesions (mean maximum diameter 9 mm) seen with MRI (no suspicious changes on breast ultrasound or mammography) were sampled using a 10-gauge vacuum-assisted breast biopsy (VAB) device under MRI guidance. Histology of biopsy specimens was compared with final histology after surgery or with follow-up in benign lesions.

RESULTS

Technical success was achieved in all biopsies. Histological results from VAB revealed malignancy in 15 lesions (32%), atypical ductal hyperplasia in four lesions (8%) and benign findings in 28 lesions (60%). One of four lesions with atypical ductal hyperplasia was upgraded to ductal carcinoma in situ after surgery. One of seven lesions showing ductal carcinoma was upgraded to invasive carcinoma after surgery. Two lesions diagnosed as infiltrating carcinoma by VAB were not validated at excisional biopsy due to complete removal of the lesion during the procedure. During the follow-up (mean 18 months) of histologically benign lesions, we observed no cases of breast cancer development. Because of morphological changes on follow-up MRI scans, two lesions underwent surgical excision, which confirmed their benign nature. Besides minor complications (massive bleeding, n = 1) requiring no further therapeutic intervention, no complications occurred.

CONCLUSIONS

MRI-guided biopsy of breast lesions using a handheld vacuum-assisted device is a safe and effective method for the workup of suspicious lesions seen on breast MRI alone.

Authors+Show Affiliations

Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Terapia Radiante, Policlinico Universitario Tor Vergata (PTV), Viale Oxford 81, 00133, Roma, Italy. tommasoperretta@libero.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng ita

PubMed ID

18633687

Citation

Perretta, T, et al. "MR Imaging-guided 10-gauge Vacuum-assisted Breast Biopsy: Histological Characterisation." La Radiologia Medica, vol. 113, no. 6, 2008, pp. 830-40.
Perretta T, Pistolese CA, Bolacchi F, et al. MR imaging-guided 10-gauge vacuum-assisted breast biopsy: histological characterisation. Radiol Med. 2008;113(6):830-40.
Perretta, T., Pistolese, C. A., Bolacchi, F., Cossu, E., Fiaschetti, V., & Simonetti, G. (2008). MR imaging-guided 10-gauge vacuum-assisted breast biopsy: histological characterisation. La Radiologia Medica, 113(6), 830-40. https://doi.org/10.1007/s11547-008-0289-y
Perretta T, et al. MR Imaging-guided 10-gauge Vacuum-assisted Breast Biopsy: Histological Characterisation. Radiol Med. 2008;113(6):830-40. PubMed PMID: 18633687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MR imaging-guided 10-gauge vacuum-assisted breast biopsy: histological characterisation. AU - Perretta,T, AU - Pistolese,C A, AU - Bolacchi,F, AU - Cossu,E, AU - Fiaschetti,V, AU - Simonetti,G, Y1 - 2008/07/05/ PY - 2007/03/18/received PY - 2007/07/30/accepted PY - 2008/7/18/pubmed PY - 2008/11/14/medline PY - 2008/7/18/entrez SP - 830 EP - 40 JF - La Radiologia medica JO - Radiol Med VL - 113 IS - 6 N2 - PURPOSE: The aim of this study was to evaluate a handheld vacuum-assisted device for magnetic resonance imaging (MRI)-guided breast biopsy. MATERIALS AND METHODS: In 47 patients, a total of 47 suspicious breast lesions (mean maximum diameter 9 mm) seen with MRI (no suspicious changes on breast ultrasound or mammography) were sampled using a 10-gauge vacuum-assisted breast biopsy (VAB) device under MRI guidance. Histology of biopsy specimens was compared with final histology after surgery or with follow-up in benign lesions. RESULTS: Technical success was achieved in all biopsies. Histological results from VAB revealed malignancy in 15 lesions (32%), atypical ductal hyperplasia in four lesions (8%) and benign findings in 28 lesions (60%). One of four lesions with atypical ductal hyperplasia was upgraded to ductal carcinoma in situ after surgery. One of seven lesions showing ductal carcinoma was upgraded to invasive carcinoma after surgery. Two lesions diagnosed as infiltrating carcinoma by VAB were not validated at excisional biopsy due to complete removal of the lesion during the procedure. During the follow-up (mean 18 months) of histologically benign lesions, we observed no cases of breast cancer development. Because of morphological changes on follow-up MRI scans, two lesions underwent surgical excision, which confirmed their benign nature. Besides minor complications (massive bleeding, n = 1) requiring no further therapeutic intervention, no complications occurred. CONCLUSIONS: MRI-guided biopsy of breast lesions using a handheld vacuum-assisted device is a safe and effective method for the workup of suspicious lesions seen on breast MRI alone. SN - 0033-8362 UR - https://www.unboundmedicine.com/medline/citation/18633687/MR_imaging_guided_10_gauge_vacuum_assisted_breast_biopsy:_histological_characterisation_ L2 - https://dx.doi.org/10.1007/s11547-008-0289-y DB - PRIME DP - Unbound Medicine ER -