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Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis.
AIDS. 1991 May; 5(5):587-9.AIDS

Abstract

Toxoplasma encephalitis is the most common opportunistic infection of the central nervous system in patients with AIDS. The treatment of choice is a combination of sulfadiazine and pyrimethamine. We present here four patients with AIDS treated for toxoplasmic encephalitis who developed sulfadiazine-induced crystalluria. This complication was rapidly reversible with rehydration and urine alkalinization. Patients with AIDS treated with high doses of sulfadiazine should be adequately hydrated, and their urinary pH maintained above 7.5 to prevent sulfadiazine-induced crystalluria.

Authors+Show Affiliations

Department of Infectious Diseases, Saint-Louis Hospital, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

1863412

Citation

Molina, J M., et al. "Sulfadiazine-induced Crystalluria in AIDS Patients With Toxoplasma Encephalitis." AIDS (London, England), vol. 5, no. 5, 1991, pp. 587-9.
Molina JM, Belenfant X, Doco-Lecompte T, et al. Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis. AIDS. 1991;5(5):587-9.
Molina, J. M., Belenfant, X., Doco-Lecompte, T., Idatte, J. M., & Modai, J. (1991). Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis. AIDS (London, England), 5(5), 587-9.
Molina JM, et al. Sulfadiazine-induced Crystalluria in AIDS Patients With Toxoplasma Encephalitis. AIDS. 1991;5(5):587-9. PubMed PMID: 1863412.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis. AU - Molina,J M, AU - Belenfant,X, AU - Doco-Lecompte,T, AU - Idatte,J M, AU - Modai,J, PY - 1991/5/1/pubmed PY - 1991/5/1/medline PY - 1991/5/1/entrez SP - 587 EP - 9 JF - AIDS (London, England) JO - AIDS VL - 5 IS - 5 N2 - Toxoplasma encephalitis is the most common opportunistic infection of the central nervous system in patients with AIDS. The treatment of choice is a combination of sulfadiazine and pyrimethamine. We present here four patients with AIDS treated for toxoplasmic encephalitis who developed sulfadiazine-induced crystalluria. This complication was rapidly reversible with rehydration and urine alkalinization. Patients with AIDS treated with high doses of sulfadiazine should be adequately hydrated, and their urinary pH maintained above 7.5 to prevent sulfadiazine-induced crystalluria. SN - 0269-9370 UR - https://www.unboundmedicine.com/medline/citation/1863412/Sulfadiazine_induced_crystalluria_in_AIDS_patients_with_toxoplasma_encephalitis_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=1863412.ui DB - PRIME DP - Unbound Medicine ER -