Tags

Type your tag names separated by a space and hit enter

YidC is involved in the biogenesis of anaerobic respiratory complexes in the inner membrane of Escherichia coli.
J Biol Chem. 2008 Oct 03; 283(40):26921-7.JB

Abstract

YidC of Escherichia coli belongs to the evolutionarily conserved Oxa1/Alb3/YidC family. Members of this family have all been implicated in membrane protein biogenesis of aerobic respiratory and energy-transducing proteins. YidC is essential for the insertion of subunit c of the F(1)F(0)-ATP synthase and subunit a of cytochrome o oxidase. The aim of this study was to investigate whether YidC plays a role during anaerobic growth of Escherichia coli, specifically when either nitrate or fumarate are used as terminal electron acceptors or under fermentative conditions. The effect of YidC depletion on the growth, enzyme activities, and protein levels in the inner membrane was determined. YidC is essential for all anaerobic growth conditions tested, and this is not because of the decreased levels of F(1)F(0)-ATP synthase in the inner membrane only. The results suggest a role for YidC in the membrane biogenesis of integral membrane parts of the anaerobic respiratory chain.

Authors+Show Affiliations

Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL-9751 NN Haren, The Netherlands.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18635537

Citation

Price, Claire E., and Arnold J M. Driessen. "YidC Is Involved in the Biogenesis of Anaerobic Respiratory Complexes in the Inner Membrane of Escherichia Coli." The Journal of Biological Chemistry, vol. 283, no. 40, 2008, pp. 26921-7.
Price CE, Driessen AJ. YidC is involved in the biogenesis of anaerobic respiratory complexes in the inner membrane of Escherichia coli. J Biol Chem. 2008;283(40):26921-7.
Price, C. E., & Driessen, A. J. (2008). YidC is involved in the biogenesis of anaerobic respiratory complexes in the inner membrane of Escherichia coli. The Journal of Biological Chemistry, 283(40), 26921-7. https://doi.org/10.1074/jbc.M804490200
Price CE, Driessen AJ. YidC Is Involved in the Biogenesis of Anaerobic Respiratory Complexes in the Inner Membrane of Escherichia Coli. J Biol Chem. 2008 Oct 3;283(40):26921-7. PubMed PMID: 18635537.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - YidC is involved in the biogenesis of anaerobic respiratory complexes in the inner membrane of Escherichia coli. AU - Price,Claire E, AU - Driessen,Arnold J M, Y1 - 2008/07/17/ PY - 2008/7/19/pubmed PY - 2008/11/5/medline PY - 2008/7/19/entrez SP - 26921 EP - 7 JF - The Journal of biological chemistry JO - J. Biol. Chem. VL - 283 IS - 40 N2 - YidC of Escherichia coli belongs to the evolutionarily conserved Oxa1/Alb3/YidC family. Members of this family have all been implicated in membrane protein biogenesis of aerobic respiratory and energy-transducing proteins. YidC is essential for the insertion of subunit c of the F(1)F(0)-ATP synthase and subunit a of cytochrome o oxidase. The aim of this study was to investigate whether YidC plays a role during anaerobic growth of Escherichia coli, specifically when either nitrate or fumarate are used as terminal electron acceptors or under fermentative conditions. The effect of YidC depletion on the growth, enzyme activities, and protein levels in the inner membrane was determined. YidC is essential for all anaerobic growth conditions tested, and this is not because of the decreased levels of F(1)F(0)-ATP synthase in the inner membrane only. The results suggest a role for YidC in the membrane biogenesis of integral membrane parts of the anaerobic respiratory chain. SN - 0021-9258 UR - https://www.unboundmedicine.com/medline/citation/18635537/YidC_is_involved_in_the_biogenesis_of_anaerobic_respiratory_complexes_in_the_inner_membrane_of_Escherichia_coli_ L2 - http://www.jbc.org/cgi/pmidlookup?view=long&pmid=18635537 DB - PRIME DP - Unbound Medicine ER -