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Cutaneous manifestations of liver diseases.

Abstract

The cutaneous manifestations of liver disorders are protean. In addition to the well-recognized stigmata of liver cirrhosis, various infectious, metabolic, autoimmune, hereditary, developmental, and neoplastic liver disorders can result in various cutaneous and mucosal changes as well as in pruritus and abnormal hair and nail growth. Although many of these changes are nonspecific, some are associated with distinct liver diseases and correlate with the severity of hepatic pathology. Familiarization with the spectrum of these manifestations is important for early detection and treatment of hepatic diseases. We review the medical literature and discuss the spectrum of dermatologic manifestations of liver cirrhosis and of important liver diseases, their etiopathogenesis, significance, and treatment.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon. sg03@aub.edu.lb

    Source

    Clinics in dermatology 26:3 pg 274-82

    MeSH

    Humans
    Liver Cirrhosis
    Liver Diseases
    Skin Diseases

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    18640524

    Citation

    Ghosn, Samer H., and Abdul-Ghani Kibbi. "Cutaneous Manifestations of Liver Diseases." Clinics in Dermatology, vol. 26, no. 3, 2008, pp. 274-82.
    Ghosn SH, Kibbi AG. Cutaneous manifestations of liver diseases. Clin Dermatol. 2008;26(3):274-82.
    Ghosn, S. H., & Kibbi, A. G. (2008). Cutaneous manifestations of liver diseases. Clinics in Dermatology, 26(3), pp. 274-82. doi:10.1016/j.clindermatol.2008.02.001.
    Ghosn SH, Kibbi AG. Cutaneous Manifestations of Liver Diseases. Clin Dermatol. 2008;26(3):274-82. PubMed PMID: 18640524.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Cutaneous manifestations of liver diseases. AU - Ghosn,Samer H, AU - Kibbi,Abdul-Ghani, PY - 2008/7/22/pubmed PY - 2008/12/31/medline PY - 2008/7/22/entrez SP - 274 EP - 82 JF - Clinics in dermatology JO - Clin. Dermatol. VL - 26 IS - 3 N2 - The cutaneous manifestations of liver disorders are protean. In addition to the well-recognized stigmata of liver cirrhosis, various infectious, metabolic, autoimmune, hereditary, developmental, and neoplastic liver disorders can result in various cutaneous and mucosal changes as well as in pruritus and abnormal hair and nail growth. Although many of these changes are nonspecific, some are associated with distinct liver diseases and correlate with the severity of hepatic pathology. Familiarization with the spectrum of these manifestations is important for early detection and treatment of hepatic diseases. We review the medical literature and discuss the spectrum of dermatologic manifestations of liver cirrhosis and of important liver diseases, their etiopathogenesis, significance, and treatment. SN - 0738-081X UR - https://www.unboundmedicine.com/medline/citation/18640524/Cutaneous_manifestations_of_liver_diseases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-081X(08)00029-1 DB - PRIME DP - Unbound Medicine ER -