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Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults.
Vaccine. 2008 Sep 08; 26(38):4947-54.V

Abstract

Pneumococcal conjugate vaccine use among young children has led to significant declines in invasive pneumococcal disease in the United States, but the impact on community-acquired pneumonia is unknown. We conducted population-based pneumonia surveillance among 794,282 Group Health members before and after infant vaccine introduction in 2000. We presumptively identified pneumonia episodes using diagnosis codes assigned to medical encounters and confirmed 17,513 outpatient and 6318 hospitalized events by reviewing chest radiograph reports or hospitalization records. There was evidence for a decline in rates of both outpatient and hospitalized pneumonia in children less than 1 year of age following vaccine introduction but there were no consistent reductions in pneumonia rates among older children and adults.

Authors+Show Affiliations

Group Health Center for Health Studies, Seattle, WA, United States. nelson.jl@ghc.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

18662735

Citation

Nelson, Jennifer C., et al. "Impact of the Introduction of Pneumococcal Conjugate Vaccine On Rates of Community Acquired Pneumonia in Children and Adults." Vaccine, vol. 26, no. 38, 2008, pp. 4947-54.
Nelson JC, Jackson M, Yu O, et al. Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults. Vaccine. 2008;26(38):4947-54.
Nelson, J. C., Jackson, M., Yu, O., Whitney, C. G., Bounds, L., Bittner, R., Zavitkovsky, A., & Jackson, L. A. (2008). Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults. Vaccine, 26(38), 4947-54. https://doi.org/10.1016/j.vaccine.2008.07.016
Nelson JC, et al. Impact of the Introduction of Pneumococcal Conjugate Vaccine On Rates of Community Acquired Pneumonia in Children and Adults. Vaccine. 2008 Sep 8;26(38):4947-54. PubMed PMID: 18662735.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults. AU - Nelson,Jennifer C, AU - Jackson,Michael, AU - Yu,Onchee, AU - Whitney,Cynthia G, AU - Bounds,Lora, AU - Bittner,Rachel, AU - Zavitkovsky,Ann, AU - Jackson,Lisa A, Y1 - 2008/07/26/ PY - 2008/02/15/received PY - 2008/07/08/revised PY - 2008/07/08/accepted PY - 2008/7/30/pubmed PY - 2008/10/24/medline PY - 2008/7/30/entrez SP - 4947 EP - 54 JF - Vaccine JO - Vaccine VL - 26 IS - 38 N2 - Pneumococcal conjugate vaccine use among young children has led to significant declines in invasive pneumococcal disease in the United States, but the impact on community-acquired pneumonia is unknown. We conducted population-based pneumonia surveillance among 794,282 Group Health members before and after infant vaccine introduction in 2000. We presumptively identified pneumonia episodes using diagnosis codes assigned to medical encounters and confirmed 17,513 outpatient and 6318 hospitalized events by reviewing chest radiograph reports or hospitalization records. There was evidence for a decline in rates of both outpatient and hospitalized pneumonia in children less than 1 year of age following vaccine introduction but there were no consistent reductions in pneumonia rates among older children and adults. SN - 0264-410X UR - https://www.unboundmedicine.com/medline/citation/18662735/Impact_of_the_introduction_of_pneumococcal_conjugate_vaccine_on_rates_of_community_acquired_pneumonia_in_children_and_adults_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(08)00933-X DB - PRIME DP - Unbound Medicine ER -