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Pseudoexfoliation in a rural Burmese population: the Meiktila Eye Study.
Br J Ophthalmol. 2008 Oct; 92(10):1325-8.BJ

Abstract

AIMS

The aim of this study was to report on the prevalence and correlates of pseudoexfoliation syndrome (PXF) in a rural Burmese population.

METHODS

The study was a cross-sectional, population-based survey of the inhabitants > or =40 years in the Meiktila District. Ophthalmic examination included Snellen visual acuity, slit lamp examination, tonometry, gonioscopy, dilated fundus examination and frequency doubling perimetry.

RESULTS

In a population of 2076 subjects (4016 eyes) the prevalence of PXF was 3.4% (95% CI 2.14 to 4.67%; 78 eyes). Twelve eyes with PXF were blind. In the univariate analysis, PXF was associated with: increasing age, blindness (odds ratio (OR) 4, 95% CI 1.84 to 8.68; p<0.0004), increasing intraocular pressure (IOP) (OR 1.08, 95% CI 1.04 to 1.11; p<0.00001), nuclear cataract (OR 6.92, 95% CI 2.89 to 16.59; p<0.00001), cortical cataract (OR 4.78, 95% CI 2.37 to 9.65; p<0.00001) and the presence of an occludable angle (OR 3.05, 95% CI 1.52 to 6.13; p<0.002). In the multivariate analysis, only increasing age and IOP remained significantly associated with PXF.

CONCLUSIONS

The prevalence of PXF in the Burmese population is greater than previously reported in other East Asian populations. Increasing age and IOP are the strongest predictors of PXF, and it is associated with cataract, occludable angles and blindness.

Authors+Show Affiliations

Department of Ophthalmology, Middlemore Hospital, Auckland, New Zealand. anmar_rahman@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

18662915

Citation

Abdul-Rahman, A M., et al. "Pseudoexfoliation in a Rural Burmese Population: the Meiktila Eye Study." The British Journal of Ophthalmology, vol. 92, no. 10, 2008, pp. 1325-8.
Abdul-Rahman AM, Casson RJ, Newland HS, et al. Pseudoexfoliation in a rural Burmese population: the Meiktila Eye Study. Br J Ophthalmol. 2008;92(10):1325-8.
Abdul-Rahman, A. M., Casson, R. J., Newland, H. S., Muecke, J., McGovern, S., Aung, T. H., Selva, D., & Aung, T. (2008). Pseudoexfoliation in a rural Burmese population: the Meiktila Eye Study. The British Journal of Ophthalmology, 92(10), 1325-8. https://doi.org/10.1136/bjo.2008.141523
Abdul-Rahman AM, et al. Pseudoexfoliation in a Rural Burmese Population: the Meiktila Eye Study. Br J Ophthalmol. 2008;92(10):1325-8. PubMed PMID: 18662915.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pseudoexfoliation in a rural Burmese population: the Meiktila Eye Study. AU - Abdul-Rahman,A M, AU - Casson,R J, AU - Newland,H S, AU - Muecke,J, AU - McGovern,S, AU - Aung,T H, AU - Selva,D, AU - Aung,T, Y1 - 2008/07/28/ PY - 2008/7/30/pubmed PY - 2008/10/22/medline PY - 2008/7/30/entrez SP - 1325 EP - 8 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 92 IS - 10 N2 - AIMS: The aim of this study was to report on the prevalence and correlates of pseudoexfoliation syndrome (PXF) in a rural Burmese population. METHODS: The study was a cross-sectional, population-based survey of the inhabitants > or =40 years in the Meiktila District. Ophthalmic examination included Snellen visual acuity, slit lamp examination, tonometry, gonioscopy, dilated fundus examination and frequency doubling perimetry. RESULTS: In a population of 2076 subjects (4016 eyes) the prevalence of PXF was 3.4% (95% CI 2.14 to 4.67%; 78 eyes). Twelve eyes with PXF were blind. In the univariate analysis, PXF was associated with: increasing age, blindness (odds ratio (OR) 4, 95% CI 1.84 to 8.68; p<0.0004), increasing intraocular pressure (IOP) (OR 1.08, 95% CI 1.04 to 1.11; p<0.00001), nuclear cataract (OR 6.92, 95% CI 2.89 to 16.59; p<0.00001), cortical cataract (OR 4.78, 95% CI 2.37 to 9.65; p<0.00001) and the presence of an occludable angle (OR 3.05, 95% CI 1.52 to 6.13; p<0.002). In the multivariate analysis, only increasing age and IOP remained significantly associated with PXF. CONCLUSIONS: The prevalence of PXF in the Burmese population is greater than previously reported in other East Asian populations. Increasing age and IOP are the strongest predictors of PXF, and it is associated with cataract, occludable angles and blindness. SN - 1468-2079 UR - https://www.unboundmedicine.com/medline/citation/18662915/Pseudoexfoliation_in_a_rural_Burmese_population:_the_Meiktila_Eye_Study_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=18662915 DB - PRIME DP - Unbound Medicine ER -