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[Occupational risk factors for lung cancer--a case-control study, Lódź industrial center].
Med Pr. 2008; 59(1):25-34.MP

Abstract

BACKGROUND

The objective of this work was to investigate the association between occupational exposure and lung cancer risk based on a case-control study.

MATERIAL AND METHODS

The study of 414 primary lung cancer cases, recorded in the Lódź industrial center in the years 1998-2002, was carried out under the international multicentre case-control study, coordinated by the International Agency for Research on Cancer (IARC). The control group, composed of individuals who did not report any tobacco-related diseases or other cancers, were matched by gender and age. Data on lung cancer risk factors were derived from a questionnaire survey on life styles and occupational exposure. The detailed information on the occupational history of all the study subjects and exposure to lung carcinogens was collected and subsequently assessed by occupational hygienists. Logistic regression was used in the data analysis. Confounders, such as age, gender, education, diet and cigarette smoking were controlled in the analysis.

RESULTS

A total of 88 case patients and 79 controls had been employed in occupations and industries associated with the evidenced or suspected risk of lung cancer development. The corresponding odds ratio was 0.71 (95%CI: 0.48-1.06). The study population was mostly exposed to organic dust, lubricating oil mist, sand, mild steel dust, organic solvents and abrasives dust.

CONCLUSIONS

The present study provides evidence that occupational exposure in the investigated Lódź industrial center is responsible for a moderate increase in lung cancer risk among exposed persons. However, only a small fraction of the study population was exposed to well documented carcinogens.

Authors+Show Affiliations

Zakład Epidemiologii Srodowiskowej, Instytut Medycyny Pracy im. prof. J. Nofera, Lódź. beata_sn@imp.lodz.plNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Multicenter Study

Language

pol

PubMed ID

18663892

Citation

Swiatkowska, Beata, et al. "[Occupational Risk Factors for Lung Cancer--a Case-control Study, Lódź Industrial Center]." Medycyna Pracy, vol. 59, no. 1, 2008, pp. 25-34.
Swiatkowska B, Szeszenia-Dabrowska N, Sobala W, et al. [Occupational risk factors for lung cancer--a case-control study, Lódź industrial center]. Med Pr. 2008;59(1):25-34.
Swiatkowska, B., Szeszenia-Dabrowska, N., Sobala, W., & Wilczyńska, U. (2008). [Occupational risk factors for lung cancer--a case-control study, Lódź industrial center]. Medycyna Pracy, 59(1), 25-34.
Swiatkowska B, et al. [Occupational Risk Factors for Lung Cancer--a Case-control Study, Lódź Industrial Center]. Med Pr. 2008;59(1):25-34. PubMed PMID: 18663892.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Occupational risk factors for lung cancer--a case-control study, Lódź industrial center]. AU - Swiatkowska,Beata, AU - Szeszenia-Dabrowska,Neonila, AU - Sobala,Wojciech, AU - Wilczyńska,Urszula, PY - 2008/7/31/pubmed PY - 2008/9/17/medline PY - 2008/7/31/entrez SP - 25 EP - 34 JF - Medycyna pracy JO - Med Pr VL - 59 IS - 1 N2 - BACKGROUND: The objective of this work was to investigate the association between occupational exposure and lung cancer risk based on a case-control study. MATERIAL AND METHODS: The study of 414 primary lung cancer cases, recorded in the Lódź industrial center in the years 1998-2002, was carried out under the international multicentre case-control study, coordinated by the International Agency for Research on Cancer (IARC). The control group, composed of individuals who did not report any tobacco-related diseases or other cancers, were matched by gender and age. Data on lung cancer risk factors were derived from a questionnaire survey on life styles and occupational exposure. The detailed information on the occupational history of all the study subjects and exposure to lung carcinogens was collected and subsequently assessed by occupational hygienists. Logistic regression was used in the data analysis. Confounders, such as age, gender, education, diet and cigarette smoking were controlled in the analysis. RESULTS: A total of 88 case patients and 79 controls had been employed in occupations and industries associated with the evidenced or suspected risk of lung cancer development. The corresponding odds ratio was 0.71 (95%CI: 0.48-1.06). The study population was mostly exposed to organic dust, lubricating oil mist, sand, mild steel dust, organic solvents and abrasives dust. CONCLUSIONS: The present study provides evidence that occupational exposure in the investigated Lódź industrial center is responsible for a moderate increase in lung cancer risk among exposed persons. However, only a small fraction of the study population was exposed to well documented carcinogens. SN - 0465-5893 UR - https://www.unboundmedicine.com/medline/citation/18663892/[Occupational_risk_factors_for_lung_cancer__a_case_control_study_Lódź_industrial_center]_ L2 - http://www.diseaseinfosearch.org/result/4334 DB - PRIME DP - Unbound Medicine ER -