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[The value of erythrocytic protoporphyrin measurement for screening blood donors for iron deficiency: a decision analysis].
Rev Epidemiol Sante Publique. 1991; 39(2):157-63.RE

Abstract

Blood donors are considered as a group with increased risk of iron deficiency. Therefore it seems particularly useful to have a simple screening test at one's disposal in blood centers to detect easily early iron deficiency. Erythrocyte protoporphyrin assay on an hematofluorometer is very easy and of a low cost. So we studied its diagnostic value on a sample of 285 blood donors (131 men and 154 women). Prevalence of iron deficiency, defined by the coexistence of, at least, two abnormal indicators (serum ferritin, transferrin saturation, erythrocyte protoporphyrin, mean corpuscular volume), was 5.6% in this sample; sensitivity of erythrocyte protoporphyrin used alone was 75% and its specificity was 91.5%. We used a decision analysis to evaluate the opportunity of screening with this test, accompanied where indicated by iron supplements. The results, though preliminary, suggest that erythrocyte protoporphyrin measurement could be of interest in screening blood donors for iron deficiency.

Authors+Show Affiliations

Preziosi P
Centre de Recherche sur les Anémies Nutritionnelles (Institut Scientifique et Technique de l'Alimentation, Conservatoire National des Arts et Métiers, Paris.
Griere B
No affiliation info available
Galan P
No affiliation info available
Toulmonde E
No affiliation info available
Hercberg S
No affiliation info available

MeSH

AdolescentAdultAnemia, HypochromicBlood DonorsDecision TreesErythrocyte VolumeErythrocytesFemaleFerritinsHumansMaleMiddle AgedPredictive Value of TestsProtoporphyrinsSensitivity and SpecificityTransferrin

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

1866483

Citation

Preziosi, P, et al. "[The Value of Erythrocytic Protoporphyrin Measurement for Screening Blood Donors for Iron Deficiency: a Decision Analysis]." Revue D'epidemiologie Et De Sante Publique, vol. 39, no. 2, 1991, pp. 157-63.
Preziosi P, Griere B, Galan P, et al. [The value of erythrocytic protoporphyrin measurement for screening blood donors for iron deficiency: a decision analysis]. Rev Epidemiol Sante Publique. 1991;39(2):157-63.
Preziosi, P., Griere, B., Galan, P., Toulmonde, E., & Hercberg, S. (1991). [The value of erythrocytic protoporphyrin measurement for screening blood donors for iron deficiency: a decision analysis]. Revue D'epidemiologie Et De Sante Publique, 39(2), 157-63.
Preziosi P, et al. [The Value of Erythrocytic Protoporphyrin Measurement for Screening Blood Donors for Iron Deficiency: a Decision Analysis]. Rev Epidemiol Sante Publique. 1991;39(2):157-63. PubMed PMID: 1866483.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The value of erythrocytic protoporphyrin measurement for screening blood donors for iron deficiency: a decision analysis]. AU - Preziosi,P, AU - Griere,B, AU - Galan,P, AU - Toulmonde,E, AU - Hercberg,S, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 157 EP - 63 JF - Revue d'epidemiologie et de sante publique JO - Rev Epidemiol Sante Publique VL - 39 IS - 2 N2 - Blood donors are considered as a group with increased risk of iron deficiency. Therefore it seems particularly useful to have a simple screening test at one's disposal in blood centers to detect easily early iron deficiency. Erythrocyte protoporphyrin assay on an hematofluorometer is very easy and of a low cost. So we studied its diagnostic value on a sample of 285 blood donors (131 men and 154 women). Prevalence of iron deficiency, defined by the coexistence of, at least, two abnormal indicators (serum ferritin, transferrin saturation, erythrocyte protoporphyrin, mean corpuscular volume), was 5.6% in this sample; sensitivity of erythrocyte protoporphyrin used alone was 75% and its specificity was 91.5%. We used a decision analysis to evaluate the opportunity of screening with this test, accompanied where indicated by iron supplements. The results, though preliminary, suggest that erythrocyte protoporphyrin measurement could be of interest in screening blood donors for iron deficiency. SN - 0398-7620 UR - https://www.unboundmedicine.com/medline/citation/1866483/[The_value_of_erythrocytic_protoporphyrin_measurement_for_screening_blood_donors_for_iron_deficiency:_a_decision_analysis]_ DB - PRIME DP - Unbound Medicine ER -