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Challenges with using chronic disease endpoints in setting dietary reference intakes.

Abstract

Since 1941, the recommended dietary allowances (RDAs) in the United States have been based on the goal of maintaining health in the country's population. There has been a growing body of evidence to support the role of diet in reducing the risk of chronic diseases. For this reason, there has been recent emphasis on considering data on chronic disease endpoints for setting dietary reference intakes (DRIs). Despite this emphasis, none of the RDAs set during the DRI review were based on chronic disease risk. However, chronic disease risk was considered for determining adequate intakes and even some acceptable macronutrient distribution ranges. This article discusses the application of and challenges associated with using chronic disease endpoints in setting DRIs.

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  • Publisher Full Text
  • Publisher Full Text
  • Authors+Show Affiliations

    Division of Nutrition Programs and Labeling, US Food and Drug Administration, College Park, MD 20740, USA. paula.trumbo@fda.hhs.gov

    Source

    Nutrition reviews 66:8 2008 Aug pg 459-64

    MeSH

    Chronic Disease
    Diet
    Humans
    Nutrition Policy
    Nutritional Requirements
    Reference Values
    Risk Factors

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    18667007

    Citation

    Trumbo, Paula R.. "Challenges With Using Chronic Disease Endpoints in Setting Dietary Reference Intakes." Nutrition Reviews, vol. 66, no. 8, 2008, pp. 459-64.
    Trumbo PR. Challenges with using chronic disease endpoints in setting dietary reference intakes. Nutr Rev. 2008;66(8):459-64.
    Trumbo, P. R. (2008). Challenges with using chronic disease endpoints in setting dietary reference intakes. Nutrition Reviews, 66(8), pp. 459-64. doi:10.1111/j.1753-4887.2008.00077.x.
    Trumbo PR. Challenges With Using Chronic Disease Endpoints in Setting Dietary Reference Intakes. Nutr Rev. 2008;66(8):459-64. PubMed PMID: 18667007.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Challenges with using chronic disease endpoints in setting dietary reference intakes. A1 - Trumbo,Paula R, PY - 2008/8/1/pubmed PY - 2009/1/13/medline PY - 2008/8/1/entrez SP - 459 EP - 64 JF - Nutrition reviews JO - Nutr. Rev. VL - 66 IS - 8 N2 - Since 1941, the recommended dietary allowances (RDAs) in the United States have been based on the goal of maintaining health in the country's population. There has been a growing body of evidence to support the role of diet in reducing the risk of chronic diseases. For this reason, there has been recent emphasis on considering data on chronic disease endpoints for setting dietary reference intakes (DRIs). Despite this emphasis, none of the RDAs set during the DRI review were based on chronic disease risk. However, chronic disease risk was considered for determining adequate intakes and even some acceptable macronutrient distribution ranges. This article discusses the application of and challenges associated with using chronic disease endpoints in setting DRIs. SN - 1753-4887 UR - https://www.unboundmedicine.com/medline/citation/18667007/Challenges_with_using_chronic_disease_endpoints_in_setting_dietary_reference_intakes_ L2 - https://academic.oup.com/nutritionreviews/article-lookup/doi/10.1111/j.1753-4887.2008.00077.x DB - PRIME DP - Unbound Medicine ER -