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Ocular and systemic factors related to intraocular pressure in Japanese adults: the Tajimi study.
Br J Ophthalmol 2008; 92(9):1175-9BJ

Abstract

BACKGROUND

As intraocular pressure (IOP) and age are consistent risk factors of glaucoma, it is of special interest to know the association between IOP and possibly relating factors including age in Japan where a high prevalence of normal-tension glaucoma has been reported. The aim of this report was to evaluate the distribution of and factors related to applanation IOP in a population-based study in Japan.

METHODS

A randomly sampled group of 3021 residents (response rate 78.1%) of Tajimi City, aged 40 years or older, underwent screening examinations including measurements of IOP with Goldmann applanation tonometry and central corneal thickness.

RESULTS

Among right eyes without glaucoma, suspected glaucoma or other disorders which could affect correct IOP measurements, IOP averaged 14.6 (SD 2.7) and 14.5 (2.5) mm Hg in men and women, respectively, with no significant intergender difference (p = 0.342). Multiple regression analyses revealed that age was significantly negatively correlated with IOP (non-standardised beta (B) = -0.020/year, p = 0.0001). Higher body mass index (B = 0.14/BMI, p<0.0001), higher mean blood pressure (B = 0.022/mm Hg, p<0.0001), history of diabetes (p = 0.0019), thicker cornea (B = 0.014/microm, p<0.0001), higher myopia (B = 0.055/dioptres, p = 0.0043) and steeper corneal curvature (B = -0.72/mm, p = 0.0002) were also significantly correlated with higher IOP.

CONCLUSIONS

In an adult Japanese population, applanation IOP averaged 14.5 mm Hg and was negatively correlated with age after adjusting for other related factors. A positive correlation between IOP and myopia was found.

Authors+Show Affiliations

Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan. mekawase@gifu-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18669541

Citation

Kawase, K, et al. "Ocular and Systemic Factors Related to Intraocular Pressure in Japanese Adults: the Tajimi Study." The British Journal of Ophthalmology, vol. 92, no. 9, 2008, pp. 1175-9.
Kawase K, Tomidokoro A, Araie M, et al. Ocular and systemic factors related to intraocular pressure in Japanese adults: the Tajimi study. Br J Ophthalmol. 2008;92(9):1175-9.
Kawase, K., Tomidokoro, A., Araie, M., Iwase, A., & Yamamoto, T. (2008). Ocular and systemic factors related to intraocular pressure in Japanese adults: the Tajimi study. The British Journal of Ophthalmology, 92(9), pp. 1175-9. doi:10.1136/bjo.2007.128819.
Kawase K, et al. Ocular and Systemic Factors Related to Intraocular Pressure in Japanese Adults: the Tajimi Study. Br J Ophthalmol. 2008;92(9):1175-9. PubMed PMID: 18669541.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ocular and systemic factors related to intraocular pressure in Japanese adults: the Tajimi study. AU - Kawase,K, AU - Tomidokoro,A, AU - Araie,M, AU - Iwase,A, AU - Yamamoto,T, AU - ,, AU - ,, Y1 - 2008/07/31/ PY - 2008/8/2/pubmed PY - 2008/10/2/medline PY - 2008/8/2/entrez SP - 1175 EP - 9 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 92 IS - 9 N2 - BACKGROUND: As intraocular pressure (IOP) and age are consistent risk factors of glaucoma, it is of special interest to know the association between IOP and possibly relating factors including age in Japan where a high prevalence of normal-tension glaucoma has been reported. The aim of this report was to evaluate the distribution of and factors related to applanation IOP in a population-based study in Japan. METHODS: A randomly sampled group of 3021 residents (response rate 78.1%) of Tajimi City, aged 40 years or older, underwent screening examinations including measurements of IOP with Goldmann applanation tonometry and central corneal thickness. RESULTS: Among right eyes without glaucoma, suspected glaucoma or other disorders which could affect correct IOP measurements, IOP averaged 14.6 (SD 2.7) and 14.5 (2.5) mm Hg in men and women, respectively, with no significant intergender difference (p = 0.342). Multiple regression analyses revealed that age was significantly negatively correlated with IOP (non-standardised beta (B) = -0.020/year, p = 0.0001). Higher body mass index (B = 0.14/BMI, p<0.0001), higher mean blood pressure (B = 0.022/mm Hg, p<0.0001), history of diabetes (p = 0.0019), thicker cornea (B = 0.014/microm, p<0.0001), higher myopia (B = 0.055/dioptres, p = 0.0043) and steeper corneal curvature (B = -0.72/mm, p = 0.0002) were also significantly correlated with higher IOP. CONCLUSIONS: In an adult Japanese population, applanation IOP averaged 14.5 mm Hg and was negatively correlated with age after adjusting for other related factors. A positive correlation between IOP and myopia was found. SN - 1468-2079 UR - https://www.unboundmedicine.com/medline/citation/18669541/Ocular_and_systemic_factors_related_to_intraocular_pressure_in_Japanese_adults:_the_Tajimi_study_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=18669541 DB - PRIME DP - Unbound Medicine ER -