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Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers.
Transplant Proc. 2008 Jul-Aug; 40(6):1814-5.TP

Abstract

BACKGROUND

The use of the Model for End-stage Liver Disease (MELD) score to prioritize patients on liver waiting lists and to share organs among centers was effective according to US data, but few reports are available in Europe.

MATERIALS AND METHODS

We evaluated the outcome of 887 patients listed between April 2004 and July 2006 in a common list by two transplant centers (University of Bologna [BO] and University of Modena [MO] ordered according to the MELD system. Patients with hepatocellular carcinoma had a score calculated according to their real MELD, tumor stage, and waiting time.

RESULTS

Five hundred eighty-six (67%) patients were listed from BO and 291 (33%) from MO. The clinical features of recipients (sex, age, blood group, and real MELD) were comparable between centers. The number of liver transplantations performed was 307, and 273 (89%) recipients had a calculated MELD >or=20. Liver transplantations were equally distributed according to the number of patients listed: 215 out of 586 (36.7%) for BO and 92 out of 291 (31.6%) for MO. The median real MELD of patients transplanted was 20, and 246 out of 307 (80.1%) grafts transplanted were functioning. The dropouts from the list were 124 (14%), and 87 (70%) of these patients had a calculated MELD >or=20.

CONCLUSION

The MELD system was effective to share livers among the two Italian centers. According to this policy, livers were allocated to the recipients with the highest probability of dropout and who had a satisfactory survival after liver transplantation.

Authors+Show Affiliations

Department of Liver and Multi-organ Transplantation, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. mrava1@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18675057

Citation

Ravaioli, M, et al. "Model for End-Stage Liver Disease (MELD) System to Allocate and to Share Livers: Experience of Two Italian Centers." Transplantation Proceedings, vol. 40, no. 6, 2008, pp. 1814-5.
Ravaioli M, Masetti M, Dazzi A, et al. Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers. Transplant Proc. 2008;40(6):1814-5.
Ravaioli, M., Masetti, M., Dazzi, A., Romano, A., Spaggiari, M., Grazi, G. L., Ercolani, G., Cescon, M., Di Gioia, P., De Ruvo, N., Montalti, R., Ballarin, R., Di Benedetto, F., Ridolfi, L., Alvaro, N., Ramacciato, G., Morelli, C., Gerunda, E., & Pinna, A. D. (2008). Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers. Transplantation Proceedings, 40(6), 1814-5. https://doi.org/10.1016/j.transproceed.2008.05.053
Ravaioli M, et al. Model for End-Stage Liver Disease (MELD) System to Allocate and to Share Livers: Experience of Two Italian Centers. Transplant Proc. 2008 Jul-Aug;40(6):1814-5. PubMed PMID: 18675057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers. AU - Ravaioli,M, AU - Masetti,M, AU - Dazzi,A, AU - Romano,A, AU - Spaggiari,M, AU - Grazi,G L, AU - Ercolani,G, AU - Cescon,M, AU - Di Gioia,P, AU - De Ruvo,N, AU - Montalti,R, AU - Ballarin,R, AU - Di Benedetto,F, AU - Ridolfi,L, AU - Alvaro,N, AU - Ramacciato,G, AU - Morelli,C, AU - Gerunda,E, AU - Pinna,A D, PY - 2008/8/5/pubmed PY - 2008/10/1/medline PY - 2008/8/5/entrez SP - 1814 EP - 5 JF - Transplantation proceedings JO - Transplant Proc VL - 40 IS - 6 N2 - BACKGROUND: The use of the Model for End-stage Liver Disease (MELD) score to prioritize patients on liver waiting lists and to share organs among centers was effective according to US data, but few reports are available in Europe. MATERIALS AND METHODS: We evaluated the outcome of 887 patients listed between April 2004 and July 2006 in a common list by two transplant centers (University of Bologna [BO] and University of Modena [MO] ordered according to the MELD system. Patients with hepatocellular carcinoma had a score calculated according to their real MELD, tumor stage, and waiting time. RESULTS: Five hundred eighty-six (67%) patients were listed from BO and 291 (33%) from MO. The clinical features of recipients (sex, age, blood group, and real MELD) were comparable between centers. The number of liver transplantations performed was 307, and 273 (89%) recipients had a calculated MELD >or=20. Liver transplantations were equally distributed according to the number of patients listed: 215 out of 586 (36.7%) for BO and 92 out of 291 (31.6%) for MO. The median real MELD of patients transplanted was 20, and 246 out of 307 (80.1%) grafts transplanted were functioning. The dropouts from the list were 124 (14%), and 87 (70%) of these patients had a calculated MELD >or=20. CONCLUSION: The MELD system was effective to share livers among the two Italian centers. According to this policy, livers were allocated to the recipients with the highest probability of dropout and who had a satisfactory survival after liver transplantation. SN - 0041-1345 UR - https://www.unboundmedicine.com/medline/citation/18675057/Model_for_End_Stage_Liver_Disease__MELD__system_to_allocate_and_to_share_livers:_experience_of_two_Italian_centers_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-1345(08)00636-2 DB - PRIME DP - Unbound Medicine ER -