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Irritable bowel syndrome: an international study of symptoms in eight countries.
Eur J Gastroenterol Hepatol. 2008 Jul; 20(7):659-67.EJ

Abstract

OBJECTIVES

This report is a preliminary comparative study of irritable bowel syndrome symptoms in eight countries, USA, Mexico, Canada, England, Italy, Israel, India, and China. We also assessed global symptom patterns and correlations and relationships to several psychosocial variables.

METHODS

Two hundred and thirty-nine participants completed a bowel symptom scale composed of four symptoms, abdominal pain or discomfort, bloating, diarrhea, and constipation as well as two psychosocial questionnaires, quality of relationship and attribution of symptoms to physical or emotional factors.

RESULTS

Pain score in Italy, with the least urban population, was significantly higher than six of the seven other countries whereas it was lowest in India and England. Bloating was highest in Italy and constipation was highest in Mexico, both significantly higher than five other countries. Diarrhea was higher in China than five other countries. All significance values were P<0.05. Globally, diarrhea was less common than constipation, P<0.001 and bloating significantly correlated with constipation as well with pain, P<0.05. Composite analysis of psychosocial variables and symptoms indicated that family conflict correlated directly, P<0.05, whereas family support correlated indirectly, P<0.01, with pain and bloating. Pain, bloating and diarrhea were significantly attributed to physical etiology, P<0.01, whereas only diarrhea was attributed to emotional cause, P<0.05.

CONCLUSION

This study suggests that there are significant variations in irritable bowel syndrome symptoms in different geographic locations around the world. Various hypotheses that may explain our data such as cultural beliefs, gut contamination, urban and rural location, dietary practice, and psychosocial factors should be further investigated.

Authors+Show Affiliations

Division of Gastroenterology, Mt. Sinai School of Medicine, New York University, New York, USA. cgerson@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18679069

Citation

Gerson, Charles D., et al. "Irritable Bowel Syndrome: an International Study of Symptoms in Eight Countries." European Journal of Gastroenterology & Hepatology, vol. 20, no. 7, 2008, pp. 659-67.
Gerson CD, Gerson MJ, Awad RA, et al. Irritable bowel syndrome: an international study of symptoms in eight countries. Eur J Gastroenterol Hepatol. 2008;20(7):659-67.
Gerson, C. D., Gerson, M. J., Awad, R. A., Chowdhury, A., Dancey, C., Poitras, P., Porcelli, P., Sperber, A., & Wang, W. A. (2008). Irritable bowel syndrome: an international study of symptoms in eight countries. European Journal of Gastroenterology & Hepatology, 20(7), 659-67. https://doi.org/10.1097/MEG.0b013e3282f53a24
Gerson CD, et al. Irritable Bowel Syndrome: an International Study of Symptoms in Eight Countries. Eur J Gastroenterol Hepatol. 2008;20(7):659-67. PubMed PMID: 18679069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Irritable bowel syndrome: an international study of symptoms in eight countries. AU - Gerson,Charles D, AU - Gerson,Mary-Joan, AU - Awad,Richard A, AU - Chowdhury,Abhijit, AU - Dancey,Christine, AU - Poitras,Pierre, AU - Porcelli,Piero, AU - Sperber,Ami, AU - Wang,Wei-An, PY - 2008/8/6/pubmed PY - 2009/3/17/medline PY - 2008/8/6/entrez SP - 659 EP - 67 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 20 IS - 7 N2 - OBJECTIVES: This report is a preliminary comparative study of irritable bowel syndrome symptoms in eight countries, USA, Mexico, Canada, England, Italy, Israel, India, and China. We also assessed global symptom patterns and correlations and relationships to several psychosocial variables. METHODS: Two hundred and thirty-nine participants completed a bowel symptom scale composed of four symptoms, abdominal pain or discomfort, bloating, diarrhea, and constipation as well as two psychosocial questionnaires, quality of relationship and attribution of symptoms to physical or emotional factors. RESULTS: Pain score in Italy, with the least urban population, was significantly higher than six of the seven other countries whereas it was lowest in India and England. Bloating was highest in Italy and constipation was highest in Mexico, both significantly higher than five other countries. Diarrhea was higher in China than five other countries. All significance values were P<0.05. Globally, diarrhea was less common than constipation, P<0.001 and bloating significantly correlated with constipation as well with pain, P<0.05. Composite analysis of psychosocial variables and symptoms indicated that family conflict correlated directly, P<0.05, whereas family support correlated indirectly, P<0.01, with pain and bloating. Pain, bloating and diarrhea were significantly attributed to physical etiology, P<0.01, whereas only diarrhea was attributed to emotional cause, P<0.05. CONCLUSION: This study suggests that there are significant variations in irritable bowel syndrome symptoms in different geographic locations around the world. Various hypotheses that may explain our data such as cultural beliefs, gut contamination, urban and rural location, dietary practice, and psychosocial factors should be further investigated. SN - 0954-691X UR - https://www.unboundmedicine.com/medline/citation/18679069/Irritable_bowel_syndrome:_an_international_study_of_symptoms_in_eight_countries_ DB - PRIME DP - Unbound Medicine ER -